Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57747	Gsk-461364	GSE92742	NPC	Human	24h	10uM	EID0319

Response Information :

Types	Number	Response transcription factors
Up-regulation	152	CEBPD; CCNH; TBX2; ARID5B; NR1H2; NFATC4; RBM39; SOX3; SNAPC4; SOX13; ZFP36L2; THRB; GATA6; DEK; TTF1; HOXA11; PEX14; TEAD4; RXRA; ZZZ3; MYBL1; BHLHE41; RAD21; MED27; NR4A2; BNC1; ZNF394; ATN1; SNAI2; SOX17; ZNF682; ZNF165; RARG; ZNF16; ZBTB43; PHIP; ZNF180; NR1H4; RYBP; TRIB3; HSF1; PKNOX2; NR1H3; IRF9; NFYA; SP140L; WT1; ENY2; CEBPB; USP16; ZNF33B; ZBTB1; NAB2; CARHSP1; PTTG1; SOX18; MYRF; PCGF1; YBX3; TAF12; FHL2; KLF11; ZNF136; ZBED2; ZNF273; HIPK2; ZNF331; PQBP1; ZNF222; ZNF665; BNC2; KLF4; ERBB2; PSMC3; ZNF232; RUNX1; ETS1; COPS5; ATF5; ZSCAN31; ZSCAN9; CBX4; CALR; OSR2; MED21; TDP2; GMNN; SSBP2; PAWR; CDK7; PFDN5; EN1; ZNF274; TRPS1; HBP1; DLX5; TCF7L2; ZNF239; IFI16; BTG1; NPAS2; CENPF; ILF2; CD3D; EHF; EPAS1; PBX3; TAF9B; CEBPG; ELF4; ZNF266; ZHX2; IRF6; POLR3C; DMTF1; YAP1; SUMO1; TFAP2C; MEIS2; FOSL1; TCEA2; ETV5; KLF3; PCGF3; NPM1; INSR; FOXF2; ZNF43; HMGB2; MAFG; ZNF131; ZNF544; ITGB3BP; CUX1; HMGN3; PEX2; RORA; NFE2L2; ZNF44; ZNF611; MBD2; TXNIP; EGR2; HHEX; FOXN3; SOX9; NR2F6; APEX1; ZMIZ1; ZNF91; DNMT1; MTA1
Down-regulation	162	BMI1; TCF4; RHOA; EED; SIAH2; ATF2; BASP1; DNMT3B; PSIP1; RBPMS; RFX7; MEOX2; BRCA1; HSF2; HLX; HMG20A; ZNF292; FOXJ3; PSMC3IP; SMARCA1; POU4F1; TBL1X; SMARCA5; ZMIZ2; SMARCC1; KAT7; MED4; ZFP64; ZNF358; TCF12; C1D; SMAD4; RNF10; ASCL1; PATZ1; MDM2; ZBTB18; USF2; KDM4A; UBP1; CTR9; ELK1; TFEB; ZEB2; KLF2; ZNF783; TGFB1I1; CDK8; UBE2B; PHF8; ASH2L; POU2F2; NUP62; NFKB1; PRKDC; RBM14; ZNF574; TCF15; TTF2; TOX3; NFE2L1; ALX1; KDM2A; KLF1; CARM1; RNF111; MSC; TBPL1; HEY1; ZNF672; ZNF189; CERS6; CHD3; POU5F1B; IRF7; NCOR2; POLR2A; LOXL2; ARID4A; SMAD1; TRIM16; ZKSCAN7; RELA; ZNF410; BAZ2A; IKBKAP; CTNNB1; CRY1; SUB1; MAML1; ZMYM2; BATF; BCL3; TFAP2A; HLTF; HIVEP2; TFCP2L1; TSC22D2; MAGED1; TSC22D1; LMCD1; PCGF2; PLAGL1; FOXD1; TRIM22; CBX3; ID3; IRF8; IRF5; BAZ2B; NCOA1; HOXA1; TLE4; ELK3; EYA1; IRF4; HNRNPD; ZNF423; STAT3; MAZ; ID2; ZNF468; TRIM28; PIR; PBX1; EYA2; BCL11B; SIX1; DACH1; ETV1; MYCBP; MED1; BRD8; NAB1; ZSCAN18; ISL1; SP3; FOXO1; RBBP5; PAX5; INSM1; AEBP1; EGR1; MSX1; ZNF587; ID4; SETD2; HOXC6; RUNX3; KAT6A; SMARCA2; MYB; MYCL; USP22; STAT6; MAF; HTATIP2; FOSB; CEBPA; NR2F1; THAP11; NFKB2