Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57743	Azd-7762	GSE92742	NPC	Human	24h	10uM	EID0319

Response Information :

Types	Number	Response transcription factors
Up-regulation	152	NFATC4; RAD21; NFATC3; TRPS1; FOS; BRD4; TCFL5; ETS1; EHF; CCNH; WNT4; ZFP36L2; CRTC1; ZNF589; PGR; ZNF467; RORC; ZNF654; SMAD4; PRDM2; TLX3; PDLIM1; NFIC; SOX5; ZFHX3; TOX; CNOT3; VGLL1; HOXA5; INSR; ARNT2; TFAP2A; SAP130; BHLHE41; TGFB1; SOX13; JUND; HOXB1; ZZZ3; LHX3; TAF4B; SP140L; SMARCB1; BNC1; SOX17; TP63; TFAP2C; EN1; WWC1; NCOA6; BAZ2A; ZHX2; GTF3A; TRIB3; ASCL1; CNBP; ZBED2; BRD7; NEUROD1; IRF6; NKX2-1; MED21; RARA; SNAI2; HSF1; NR1D2; PCGF1; IL16; KLF13; MEIS2; CDX1; SIN3B; PBX3; GATA6; IFI16; CTBP2; WDR77; CBX4; MYBL1; SOX18; ZNF580; JUP; OVOL2; SPI1; TTF2; ZNF816; SMARCC2; C1D; FOXF2; CAPN15; HHEX; NFYC; MBD2; PMS1; HOXD1; TADA3; ZNF148; HLF; ZMYND11; SLC2A4RG; ATN1; SHOX2; IRF9; ELF4; GMNN; MAML1; SOX9; SUMO1; IRF5; CAMTA1; VEZF1; HOXD3; POLR3C; KLF11; TDP2; ETV5; HDAC9; ZFPM2; ZNF217; HEY2; KLF2; NR4A1; CDK7; DACH1; SMAD2; CD3D; ETV1; FOXN3; MLXIP; ERBB4; CTBP1; ZNF91; SMARCA2; FLNA; ZBTB16; TBX3; HMGN3; MAF; ZFP36L1; CHD7; TCF7L2; HDAC1; ID4; TRIM29; NFIB; TCEA2; ELF5; SUZ12; WT1; NR2F1; KAT6A; MTA1
Down-regulation	143	BASP1; EZH2; SOX11; BTG1; DNMT3B; ZBTB1; SOX4; NCOA4; NFE2L1; RHOA; TOX3; KDM5B; PCGF2; FOXD1; HDAC2; NR1H3; BRD3; LOXL2; CASZ1; TCF4; ZNF135; HDAC5; TBP; BATF3; NONO; ZNF432; ZNF263; ZNF692; ZNF177; USP16; RUNX1; TRIM27; HOXB2; POU3F2; SIX1; KLF12; SIAH2; BCLAF1; CHD1; CENPF; MAGED1; MAFF; MYCBP; ZEB1; SOX15; HIVEP2; ZKSCAN7; RBBP4; TRIM16; ZNF117; IRF7; ORC2; SMAD3; REXO4; KLF1; CDYL; ADNP2; ZNF302; KAT7; ZNF536; NFATC1; RBM14; REST; PLAG1; SMARCA5; ZNF606; EDF1; PKNOX1; NEDD8; PCGF3; ZNF85; WHSC1; TAF7; IRF4; BRD8; ZNF107; BMI1; MEOX2; KDM2A; UBE2I; GTF2I; SAP18; HOXC6; TAF10; ALX1; PBXIP1; NFE2; CHD3; TBL1XR1; BAZ1A; FOXG1; HIPK1; AFF1; PIAS3; CTR9; PAXBP1; HMBOX1; GTF2IRD1; ZNF124; CERS6; ZSCAN18; JARID2; RBPJ; ARID4B; ZMIZ2; MYT1L; HOXB7; CALR; MSX1; MNAT1; ZNF266; ZNF274; ATF5; TXNIP; ZNF22; STAT3; NFE2L2; EGR1; LITAF; ZNF146; ZBTB18; DAXX; NUP62; REPIN1; FOXO1; ZNF544; MYCL; HMGB3; EGR4; SATB2; RUVBL2; EGR3; IRX5; SIX2; OLIG2; ZNF652; FOSL1; CEBPA; MNDA; MAFB; THAP11; NFKB2; ZNF586