Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57741	Cyclopamine	GSE92742	NPC	Human	24h	10uM	EID0319

Response Information :

Types	Number	Response transcription factors
Up-regulation	83	HOXC10; CERS4; SALL1; CARM1; TCF4; ERBB2; ZNF292; CNOT2; JUP; ZFHX4; HEY2; YBX3; DDX17; POU2F1; LOXL2; MED25; RBM39; DDIT3; E2F6; YEATS2; PBX2; BHLHE40; ZNF589; PMF1; MYRF; MYOG; CREG1; ZFP36L2; LZTS1; PA2G4; GATAD2A; MED24; SIX3; DMTF1; HDAC7; PFDN5; XRCC6; CREB3L2; TFCP2; LYL1; HAND1; ZEB1; CBX6; BACH1; EVX1; MSX1; IRF7; HOXC6; HOXC4; CITED1; EPAS1; AIP; DNAJC1; CBFA2T3; TRIB3; GTF3A; NFKB2; PSMC3; ETV5; CUX1; COPS2; TP53; HEY1; KMT2A; SREBF1; BTG1; SMAD1; CEBPZ; DLX5; CALR; SOX10; ESR1; NR2F6; TCEA2; ZMIZ1; EYA1; MYB; IRF8; NR2F2; EMX2; DNMT1; MTA1; EGR1
Down-regulation	135	BASP1; UBE2B; PLAGL2; ZBTB11; KLF5; SOX3; PBX3; NPAS2; HLF; TGS1; TTF2; TFE3; HIPK1; CREBL2; IRF2; IRF1; MYT1L; ZSCAN18; CHD1; IKBKAP; ING2; TAF9B; ID3; KLF4; THAP10; TRIM32; BRIP1; NEUROD1; CRY1; SOX9; NR1H3; NR1D2; NFIX; ZMYND11; TBPL1; THRA; HIVEP2; THAP1; ELF4; ZNF419; CD3D; ZNF140; GATA6; FOSB; TSC22D2; NFIB; RNF6; MTDH; SSBP2; BCL11B; CITED2; ZNF304; BMI1; TOX; SMARCA2; MEN1; TEAD1; AHR; NRBF2; TFCP2L1; ZNF200; ZNF267; INSM1; TFAM; ZNF468; CBX3; ATF3; FOXA1; MEIS1; ZBED2; UBP1; ZNF217; ZIC1; NANOG; RBBP8; RNF138; ZNF83; NONO; ZNF14; GMNN; FOXG1; SSX1; PBX1; RFX5; SUB1; PRKDC; BHLHE41; VEZF1; ID4; ERBB4; ZNF274; STAT6; SAP30; SATB2; ZNF665; KAT6A; NKX3-1; MAFB; MYCBP; NCOA3; NFE2L2; CCNE1; SIX1; RBPMS; ZNF91; RUNX3; ID2; BAZ1A; SALL2; MEIS2; RBL2; ZNF430; PAX6; NUP62; POU2AF1; TOX3; PEG3; TOB1; USP22; E2F3; TRIM29; ZNF12; ETV1; MYCL; TWIST1; ETS2; HMGN3; TRIM16; BBX; PLAGL1; STAT3; ST18; MNAT1; CEBPA; ZNF586