Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57738	Sitagliptin	GSE92742	NPC	Human	24h	10uM	EID0318

Response Information :

Types	Number	Response transcription factors
Up-regulation	253	MEF2C; NR1H2; IRF6; ZNF165; CEBPD; SOX18; SPDEF; TAF5L; PBXIP1; ZSCAN31; TRIB3; ETS1; INSR; FEZF2; ZNF688; NR5A1; CHD2; JUN; ZNF117; ZKSCAN4; ZFP36L2; RARG; SRCAP; ZNF232; ZNF682; NFATC4; TLX3; KLF15; GATA2; ZNF180; LHX3; VGLL1; POLR3C; HIRA; TCF21; MED12; VDR; THRB; GATA1; NR5A2; ERBB4; ZNF33B; GATA6; POU6F2; HOXD1; ECD; OVOL2; E2F8; TP73; HIPK2; MAK; NR2F6; FOXA2; ZNF141; ZNF273; ZFHX3; TFAP2A; TBX5; EMX1; IKZF3; SKIL; USP21; MED25; IFI16; AGO2; SPI1; ZNF10; MED14; HES1; ZNF345; SCRT1; HNF1A; TULP2; CREM; ZNF816; TEAD4; PRDM10; ARNTL; ZNF623; RXRG; ZBTB3; SOX13; POU4F3; GTF2A2; ZNF589; AEBP1; POU2F3; LYL1; BACH2; ZNF74; ZNF544; ZNF214; ZNF195; PGR; HSF1; ZNF467; ZNF394; MYNN; PRDM14; PRDM2; BNC2; CCNH; HSF4; SSBP3; CHD8; SRY; ZNF507; PPP1R13L; CSDC2; TULP4; PCGF1; BRD7; HIVEP1; CDK7; DNMT1; TAF9; POU1F1; ZSCAN9; ZNF135; PEG3; ATOH1; ZFP69B; ZNF124; FOXM1; BNC1; AIRE; TRPS1; ARNT2; ZNF223; MYB; SUPT3H; ZIC3; ZHX2; ELF4; KLF11; ZSCAN16; GATA4; JUP; RYBP; NFE2L3; CREB3L2; IFNB1; UBE2L3; ZNF215; ZNF667; TRIP11; TFCP2L1; ZNF552; HOXA5; ZNF415; CAMTA1; LZTR1; HMBOX1; CBFA2T3; GLI2; KDM5C; ZNF239; UBTF; PSMC3; CBFB; RORA; CALR; TFAP2C; BCL11A; SNAI2; TCEA2; STAT6; PA2G4; SMARCB1; ZNF85; SOX17; SNAPC4; NFE2; RBFOX2; GFI1; CERS4; ZNF331; ZNF835; MED20; GRHL2; SIX3; ZBED2; NFE2L2; KLF9; HIC2; HOXD3; ATN1; RREB1; TGFB1; TULP3; EN1; JUNB; CCDC59; HOXB5; CEBPG; WT1; ESR1; CNOT3; WWP1; WNT4; ILF2; CBX4; PAX5; ZNF107; FOXO1; KLF4; BTG1; FOXE1; RAD21; FOXI1; ARID1A; AHR; ELF5; TCF7L2; CBX5; SPIB; PPARD; PAWR; HOXA1; SP140L; MYRF; MNDA; CD3D; NR4A2; SOHLH2; IL16; ZBTB16; STAT4; ST18; MYCN; SMAD7; POU2AF1; FOSB; KLF6; MEIS2; ZMIZ1; SOX10; TCF7L1; TBX3; TCEA1; KLF10; BHLHE41; TRIM29; HHEX; EHF; ATF5; NFKBIB; PBX3; SMAD3; EMX2; ATF3; EGR3; EGR1
Down-regulation	280	TBP; FOXJ3; ZMYM2; TP53; HLTF; ZNF302; HSF2; NRIP1; EED; USP22; RNF4; PHF2; BASP1; PSMD9; DPF2; ATF1; RBBP4; BRD8; TSC22D2; HDAC3; CTR9; ARID4A; RHOA; CBX3; SUV39H1; PSIP1; ZIC1; E2F2; MLX; NEDD8; USF2; YBX1; FOXO4; ZEB2; NFYC; UBE2I; ZNF587; TAF9B; HSBP1; ZNF384; EDF1; MED1; NUP62; DDX5; TSC22D4; ID2; DRAP1; TCF12; MYC; NFIL3; SOX4; MDFI; HDAC6; PHF8; PCGF2; PCBD1; OLIG2; UBP1; ZNF711; UBE2B; ZMYND11; CCNA2; BCLAF1; POU3F2; NCOA6; HDAC1; TBL1X; TRIM32; BAZ2B; SETD3; ZNF146; KAT7; KDM5B; SIRT7; NFKBIA; LPIN2; TAF7; KMT5A; ETV5; PBRM1; ZBTB38; SMARCE1; SCAND1; SNW1; HCFC2; BATF3; MTA1; BAZ1A; ENO1; ZNF160; TOX; ORC2; BRCA1; SMAD6; ARNT; FOXD1; NONO; ZNF143; EZH2; BIRC2; SALL1; ZFP64; ZNF24; STAT3; VEZF1; KDM2A; GTF2IRD1; LHX1; POU2F2; ZBTB11; GABPA; PKNOX1; TLE1; LOXL2; SMAD4; ELK1; HABP4; ETV1; ZNF148; PSMC3IP; MXD4; ZNF23; RFC1; ZNF783; ARID4B; MED4; EP300; SIAH2; TSC22D1; ZNF189; TLE4; PITX2; EP400; MSX1; TBL1XR1; GMEB1; DDX17; HNRNPD; JARID2; KAT2B; YWHAB; SMARCA4; MLLT10; PIR; FOXF1; CNBP; ASCL1; TOX3; HOXB3; NAB1; SUPT4H1; BRD2; E2F6; RCOR1; CARHSP1; ZSCAN18; PIAS2; HOXC4; HMG20A; TRIM28; ZNF226; CTBP1; BMI1; SAP30; CHD1; SIX2; HOXC6; SOX9; CITED2; HMGN3; SMARCA5; DEK; EYA1; RBBP7; ZMIZ2; MNAT1; GTF2I; ELF2; ASH2L; RNF10; RFX5; SSX1; SMAD1; FLNA; TAF10; BBX; PTTG1; ALX1; HIPK3; NPM1; ZNF419; GABPB1; NRBF2; ITGB3BP; ZNF205; DNAJC1; ZZZ3; MYCBP; NFIC; HAND1; DAXX; PPARGC1A; ERBB2; KAT5; RNF141; TAF12; TCERG1; YAF2; NR2F1; ZNF516; TAF1D; FOXO3; RERE; CREB5; SOX15; RFX7; ZNF721; RAN; HMGB1; RBM14; PAX6; RBPJ; SMAD5; PHF1; TRIM16; ZBTB14; MITF; ZNF217; MAGED1; MAX; STAT5B; TRIP6; STAT1; MED6; PATZ1; SFPQ; ING3; ZNF91; TCF7; ZMYND8; SIX1; BRD4; SP3; FOXC1; ZNF14; NAB2; RBBP8; CTBP2; CRK; GTF3A; NKX3-1; RB1; EN2; PITX1; SMARCA2; ZNF266; ID3; ZBTB18; NR1D2; IRX5; POU4F1; NR2F2; ZKSCAN1; ING2; HMGA1; ZNF12; RBPMS; TOB1; HEY1; TWIST1; HLF; FOSL1; TXNIP; DMTF1; NFKB2; LEF1; HOXB7; HOXC10; ID4; ID1