Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57736	Zibotentan	GSE92742	NPC	Human	24h	10uM	EID0318

Response Information :

Types	Number	Response transcription factors
Up-regulation	55	HES1; UBE2I; KLF11; TFAP2C; CRY1; NR2F1; TXNIP; ZNF771; TCF20; PQBP1; BATF; SPI1; ARID5B; PPARD; MXD1; C1D; ZNF331; IL16; CHD1; ZNF267; RXRA; FOXC1; MNDA; FOXE1; CREB5; NR4A2; TRIB3; PSMC3IP; HDAC4; YBX3; SOX10; CREB3L2; UBE2L3; ZHX2; SIX2; SMAD3; ZFP36L2; OSR2; TCF7L2; LITAF; MYRF; MTF2; CITED2; NPAS2; HHEX; BHLHE41; AHR; NR4A1; TOB1; CTBP2; HMGA1; TP63; EGR1; NFIB; KAT6A
Down-regulation	64	CDK2; SMARCC1; TP53; ZNF281; CHD3; ZNF302; PIR; PRMT2; HMG20B; MSX1; LEF1; SMAD7; RUNX3; ZNF587; ZNF529; NRIP1; UBP1; AEBP1; JUND; TRIM24; TAF9B; CTR9; NCOA6; AES; ZNF552; STAT2; NONO; BCL11B; TDP2; SATB2; SCAND1; BAZ1A; COPS2; HEY1; SMARCA1; CTNNB1; ZFPM2; EYA2; CERS6; MITF; KLF9; SOX11; SIAH2; HOXB13; FOXA1; YWHAB; MYB; ZIC1; CRK; IRF7; ESR1; SNAI2; MECOM; ZKSCAN1; MAGED1; TGFB1I1; ZNF652; FOXF1; ZFHX4; HOXB2; SOX17; NKX3-1; HOXC6; NFKB2