Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57734	Amonafide	GSE92742	NPC	Human	24h	10uM	EID0318

Response Information :

Types	Number	Response transcription factors
Up-regulation	286	EPAS1; ZNF586; MDM2; GATA2; RELB; NFE2L2; USP16; KDM4C; RARG; JUNB; AFF4; TBX2; ZNF131; PARP1; GFI1; ZNF557; NR1H2; TAF1; ZNF614; GCFC2; KLF9; ID2; PDLIM1; ZNF536; CRTC1; FOXO4; HTATIP2; NFE2L3; ETS1; NFYA; ZNF23; PAX8; KLF15; ATOH1; IRF9; ZNF556; SPDEF; ZNF276; PBXIP1; CEBPD; NFAT5; SAFB; ZNF215; NR0B1; ZNF195; THAP11; KDM5A; HDAC9; TSC22D4; ZNF165; FHL2; LHX1; ANKRD1; FOXA2; MDM4; PIAS1; FOS; NR2C2; TRIP11; TCF3; MYRF; TXNIP; ZHX2; PRMT2; EHMT1; TLE2; NR2F1; CBFA2T3; ZNF394; GBX1; TRIM16; SIX5; ASH1L; ZNF335; ZNF75D; XBP1; PRDM1; ZNF510; MTF2; TGFB1; CDK9; TULP4; FOXN3; PML; MZF1; HOXA11; DLX5; BRWD1; PPARG; ZNF354A; DMTF1; AATF; ZNF225; PTRF; NHLH1; ZNF688; SRY; ZNF227; MXD1; STAT3; ZBTB25; CIR1; ZNF324B; ZKSCAN8; ERCC2; HMX1; EMX1; NFYB; NFX1; TOPORS; ELF1; CIZ1; FOXH1; ADRB2; TAF7L; ZBTB18; HHEX; NOC2L; SMAD5; TCF15; COPS2; TDP2; ZSCAN32; BACH2; GLI1; NRL; FOXE1; SKIL; LIMD1; SNAI1; KAT6B; RORC; ZNF273; TAF5L; ZFP36L2; EZH1; RARB; REXO4; AEBP1; BCL3; CCNT1; PROX1; BAZ2B; MNDA; MXD4; SSX1; ZNF180; ZNF211; ZNF35; APBB1; PRDM8; GTF2A1; HOXC8; ZNF770; BNC2; NR3C2; PIR; AFF1; LITAF; SIN3B; BACH1; GLI2; VDR; CBX7; CIC; CREG1; BTG1; KLF3; SAFB2; TERF1; TDRD3; SIRT2; CBL; FOSL2; PRDM14; LHX6; PAWR; PAX5; NR4A2; HIPK2; MLXIP; ZBTB7A; TP73; ZNF253; SNAPC4; ZNF430; CEBPZ; POU2AF1; PPP1R13L; NR0B2; ZBTB38; FOXF2; POU2F2; MYT1L; HOXD10; ZNF331; RB1; IL16; NFATC1; IRF4; TLE1; BAZ2A; YAP1; CHD1; POU3F1; ZIC3; HBP1; POU5F1B; RNF14; SERTAD2; HIPK1; HSF4; RBM39; RFX7; ZNF85; RNF6; OVOL2; STAT2; SPIB; EMX2; RBL2; NFKB1; PIAS3; EHMT2; CBX6; PFDN5; TAF7; EYA2; FOXI1; KLF11; BCL11B; JUN; LIN28A; E2F8; TFAM; ZNF423; TRIM29; ATF7IP; NEUROD1; SUPT3H; PRPF6; NFKBIB; SMARCD1; ZNF117; CREM; ARL2BP; CNOT3; HDAC4; RNF141; RCOR1; WWC1; JAK2; BBX; KAT2A; TFEB; OSR2; PAXBP1; GTF2I; NR1D2; ST18; TFAP2C; SSBP2; SUPT6H; HLX; EHF; ZNF589; ZEB2; WNT4; ZNF45; FOXJ1; SNAI2; PPARGC1A; MED1; FOXO1; TGIF1; WT1; ETV1; SOX10; PPARD; YBX3; MXI1; BCL11A; PEG3; ID1; NFKB2; CRK
Down-regulation	330	HDAC2; PUF60; SMARCC1; DNMT1; MAZ; MYC; DEK; EZH2; CBX3; CCNC; NONO; CENPF; PSIP1; MYBL2; ZNF587; ENO1; USP22; RNF138; INSR; KDM5B; BRCA1; RLF; RHOA; FOXM1; CDK2; IKBKAP; HMGB2; NFIL3; NRIP1; SMARCE1; ATF1; PRKDC; E2F3; SSRP1; NCOA4; NFYC; TLE4; ZNF160; ITGB3BP; PA2G4; NUP62; ZNF721; SOX11; VGLL4; ZNF248; TSC22D3; RBBP4; HDAC1; ZNF22; HMG20A; HMGXB4; UBE2I; CDYL; STAT6; EED; GTF2IRD1; BCLAF1; ZFP64; ZNF302; SMARCD2; PITX2; ZNF764; PHF20; TBL1XR1; TOX; TAF11; EGR2; PHF2; COPS5; PBX1; PBRM1; ZNF358; BIRC2; PPRC1; PMF1; YBX1; ZBTB11; TCF12; POU3F2; GMNN; SRF; TP53; PLAGL2; PBX2; DRAP1; HDAC3; REST; GABPB1; NFKBIA; SUMO1; RAD21; BTF3; TBP; BRD7; KAT8; HMGB3; HLTF; TAF1D; APEX1; SMARCA4; EWSR1; ZNF83; MXD3; CALR; ZNF32; PSMD9; SCMH1; RAN; HMG20B; CARM1; E2F2; CBX5; ZSCAN12; RFC1; HOXD9; ZNF263; HDGF; SATB1; L3MBTL1; ZNF334; GRHL2; HEY1; EN1; MBD2; RUVBL1; MEOX2; KAT5; HMGA2; TOX3; GFI1B; DDX17; DEAF1; MAFG; ENY2; ZFPM2; SAP30; ZFP36L1; BMI1; HIC2; PSMC3IP; HNRNPD; CARHSP1; THRA; LDB1; KDM4A; MAGED1; ZNF146; ZNF593; NFRKB; BRD3; TEAD3; ZNF3; SMARCC2; REL; TRIM28; TOX4; SMAD2; RBBP7; SMAD4; IRF2; OLIG2; SIX2; KAT6A; ASXL1; DPF2; ETV5; RNF2; MAFF; TBPL1; MTDH; SNW1; ZNF768; BAZ1B; ATF3; BATF3; JARID2; RXRB; ZIC1; FOXJ3; HOXC6; MYT1; PQBP1; SAP18; RFX5; RXRG; ZNF292; CHD9; ZNF611; ASH2L; HOXB7; HIF1A; NPM1; ELF4; HCFC1; RREB1; HSF2; TRIM32; TAL1; SFPQ; TGFB1I1; MED23; TFEC; HOXB5; ZNF606; TAF6; SND1; SMARCD3; STAT1; EDF1; CRY1; ZNF410; ATN1; SALL2; NR1H4; SMAD1; KLF10; LOXL2; LZTS1; ARID4B; PLAGL1; SP140L; CBFB; HOXB6; IRF8; SUPT7L; ILF2; MKL1; USP21; PREB; ZNF512B; KDM5D; ZNF133; MEN1; BRD8; CTBP1; ID4; TCF7L1; NFE2L1; ZNF274; ING2; CTBP2; UBE2B; CREB1; RBFOX2; KAT7; THAP10; TSC22D2; SUPT4H1; MMS19; RBBP5; CERS6; ARID1A; PKNOX2; EGR3; MNAT1; ZBED1; NAB2; ASCL1; TCF7; EYA1; PTTG1; PATZ1; TBL1X; CCDC59; ZNF415; SMARCA1; YWHAB; RSF1; ZNF329; AHR; ZNF24; KLF7; NKX2-2; ZNF516; RBPJ; HOXB2; UBE2L3; MECOM; ZNF217; PRRX2; DAXX; ZNF623; ZNF652; MED24; HMGA1; DDX5; SMARCB1; ELF5; NAB1; SREBF2; CDC5L; TCEA2; PITX1; LEF1; RBBP8; ZBTB16; FOXF1; TRIM22; TWIST1; ZNF148; FOXA1; NR4A1; TAF10; TRPS1; ELK3; MYCL; ISL1; ZNF44; TCEA1; MEIS1; TCF7L2; THAP4; ATF4; ERBB4; ZEB1; HIRA; IFI16; DACH1; CITED2; PBX3; SUZ12; SIX1; LMCD1; SMARCA2; STAT5B; GATA6; ZMIZ1; ABL1; SMAD3; EGR1