Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57722	Motesanib	GSE92742	NPC	Human	24h	10uM	EID0318

Response Information :

Types	Number	Response transcription factors
Up-regulation	99	HOXB5; HOXB6; ARID4A; ZNF273; ZNF32; HOXB9; PRKDC; GABPA; ZNF354A; ADRB2; HIVEP1; FOXJ2; BCLAF1; ZNF43; HOXA5; SOX3; ZNF468; TRIM22; FLI1; NKX2-2; ZBTB1; NCOA1; SALL1; CUX2; NFYB; IRF2; LPIN2; DEK; CNOT1; LIN28A; MYCN; BTG1; SOHLH2; TOX3; RBL2; KAT7; ZNF117; ZNF107; HOXB7; ZNF83; ZNF415; ZEB2; FOSL2; ZNF84; ZNF529; HOXB2; PMS1; TFCP2; TXNIP; TFAP2C; FOSL1; ZNF232; IKZF5; DLX5; MAGED1; CBFB; MEIS1; ZFP36L2; SALL2; TGIF1; DACH1; HOXA1; SMARCA2; AR; SERTAD2; MNDA; PRRX1; POU4F1; HOXB13; CRYM; IRX5; ERBB2; IRF4; KLF10; HIPK3; DLX2; MAF; HDAC4; TCEA2; FOXG1; TFEC; MYBL1; ZFP36L1; VDR; SIM2; ZNF331; TCF7L1; PURA; NKX3-1; SOX11; HOXC6; KAT6B; TBX3; TOB1; EGR3; HEY1; KAT6A; NFATC3; ASCL1
Down-regulation	85	IKBKAP; INSR; NR5A2; MAFG; FOXJ3; NFIC; KDM5D; PIAS1; ZNF771; PLAGL2; RARG; HLTF; RBPMS; TRIM16; FOXK2; CBFA2T3; C1QBP; UBP1; TSG101; ADNP; CIZ1; FOXD1; LDB1; GTF2F1; KLF7; YWHAB; JUP; TRIM28; ZNF217; SUPT4H1; SHOX2; TFAP2A; SMAD1; SCAND1; HDAC9; TGFB1I1; KLF13; TEAD1; ZNF24; ARID5B; NAB2; CTR9; NAB1; ZBTB38; PHF20; PTRF; ENY2; PRPF6; TGIF2; MYB; PITX1; MEOX1; ZNF91; BCL3; RYBP; ZHX2; IRF7; ZNF721; DNAJC1; CRK; SMAD6; CREB3L2; ZBED2; RUNX3; LITAF; CITED2; BRD2; BNC2; BRD4; NR4A1; BASP1; ZNF148; CITED1; MED13; EGR1; HHEX; FOXF1; TBPL1; RUNX1; BBX; SMAD3; ZKSCAN1; NFKB2; MEIS2; MECOM