Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57720	Saracatinib	GSE92742	NPC	Human	24h	10uM	EID0318

Response Information :

Types	Number	Response transcription factors
Up-regulation	148	TBX2; ZSCAN31; GRHL2; ZNF273; MDM2; ZNF124; ZNF292; ERG; TLE2; ZNF711; NFYA; ARRB1; ZNF614; ELF5; TAF7; ENO1; SETD2; ARID4B; TFE3; TCFL5; EPAS1; FOXK2; NCOA1; FOXC1; ZNF324; ZNF665; NR3C2; TCEB2; LIMD1; PIAS1; ABL1; SNAI1; ATN1; AGO2; MXD1; ZSCAN16; HMGB3; IRF6; NR2F1; ZNF165; NLK; ASH1L; ZNF184; PURA; TFAM; PGR; YWHAB; ZFHX3; ZSCAN32; SP1; NKX3-1; EHMT1; CAMTA2; ZNF556; NKX2-1; TSC22D2; MED21; MED13; UBE2B; TAF4B; SMARCC2; MEN1; ID1; ZNF253; CCDC59; GTF2I; RSF1; ZNF415; BCL10; ELF2; ZNF22; ZNF468; STAT5B; EZH2; NFE2L3; ZNF813; HIPK1; ZNF432; ZMIZ2; SIX6; WWC1; ESRRA; BRIP1; TBL1X; THAP11; RBPJ; TFAP2C; SMARCA5; SP2; MEF2A; RBM14; HTATIP2; HMGB2; KLF1; REPIN1; KAT7; RELA; DNMT3B; VDR; IRF1; ZNF107; ZNF551; CCNT1; BIRC2; HIC2; ZNF589; DMTF1; TBX3; NRBF2; TRIM29; NR1D2; EYA2; INSM1; YEATS2; SOX9; ZNF131; RCOR1; SIM2; UBE2L3; SIX2; FOXE1; ERBB2; TFCP2; TEAD3; HIPK3; CREB3L1; MYCL; GATA6; KLF10; PTRF; LMCD1; ZBED2; PAWR; TOX3; NANOG; NFATC3; BCL11A; JUP; ID4; NFKB2; BASP1; ASCL1; NR2F2; BBX; HLF; NFIB; KAT6A; CRK
Down-regulation	168	NR2F6; RUVBL1; IKBKAP; DNMT1; BARX1; RHOA; USP22; MYC; CNBP; MSC; HDGF; HOXB6; CENPF; ZMYM2; HOXB5; HOXC4; EP300; PEX14; MEOX2; PCGF3; KLF11; ZNF688; LDB1; SPI1; LYL1; TCEA1; SUZ12; HDAC9; HOXD1; HHEX; GTF3A; MED27; SNAI2; APEX1; NR5A2; FOXM1; PAX9; POU3F2; MLXIPL; NONO; ERCC3; C1D; NFATC4; ZNF587; PMS1; ZNF281; TCF25; ZNF500; HOXB2; ELF1; ZKSCAN4; USF2; ARNTL; CBX3; SP110; JARID2; FOXD1; DR1; ZBTB16; ARID5B; AATF; FOXO1; MEOX1; EGR2; TGFB1; ZXDC; BRCA1; CDYL; ESR1; DLX2; PBRM1; SFPQ; YBX3; BCL11B; CERS4; TDP2; HMGXB4; HOXB7; RNF6; ZNF593; HMGB1; TAF9; CITED2; TTF2; COPS5; ZBTB20; ZNF160; OLIG2; MED4; PRKDC; CHD8; CUX2; TFDP2; KAT2B; CREB1; MAFB; EGR3; NFE2L2; HOXD3; TSC22D1; ARNT2; ZNF721; ZNF580; ZNF573; PFDN5; TRIB3; PEX2; SP140L; HMGN3; HOXC6; ZNF224; TBPL1; ZNF266; CCNH; XRCC6; SCAND1; CSDE1; RBBP7; IFI16; CBFB; ZHX2; RORA; HMG20B; KLF2; ZEB1; PLAGL1; HLX; TCF7; ZMYND8; TGIF2; BTG1; FOSB; DDX17; PITX1; HOXA1; HMGA2; MED1; ETV5; BMI1; EGR1; ERBB4; TP63; RAN; ZBTB18; CREG1; LEF1; ZEB2; TLE4; TCF7L2; RB1; FOS; AHR; FOXG1; RUNX1; PAX5; SOX11; ATF5; KAT6B; ETS2; TGIF1; SOX17; CD3D; TRIP6; SMAD3; HOXC10; PEG3; TWIST1; FOSL1