Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57692	Zibotentan	GSE92742	NEU	Human	24h	10uM	EID0316

Response Information :

Types	Number	Response transcription factors
Up-regulation	125	NFKB2; IKZF1; MAX; NFKBIB; MAML1; ZNF12; DAXX; ZNF200; ARL2BP; ACTL6A; NFE2L3; NFE2L2; HLX; SIAH2; TCF25; EHF; MED21; NAB2; TAL1; RELA; CEBPB; HIPK1; NR0B2; ZNF354A; ZNF654; FOXI1; SMARCD2; MSC; RBL2; SNAPC4; E2F4; ZSCAN2; ZNF263; ITGB3BP; ATF3; DNAJC2; ARID5B; ZNF184; SRF; HHEX; TRAF6; IRF1; VGLL1; HDAC3; THAP10; CREBZF; LHX6; ZBTB39; ZXDC; CD3D; CEBPD; PRMT2; THRA; IRF6; ZSCAN32; ESR1; PNRC1; CDK2; SMARCA1; RREB1; GFI1; SIRT7; KLF9; GCFC2; PBXIP1; RNF14; AR; WT1; TGFB1I1; GATA6; PHF1; JUNB; NEUROD1; ZNF394; PEG3; TGIF1; RING1; ABT1; MNDA; KLF2; NR4A1; PIR; HOXA5; LIN28A; BCL11B; RFX5; CNOT6; OVOL2; NFYA; TBX21; HMG20B; ATF5; ELF1; TLE2; ZNF281; POU4F1; ETS2; KLF4; ELF3; TOB1; JUP; KLF6; SNAI2; FOXJ2; HES1; SUB1; TAF5L; FOXA2; RUNX3; JUN; SP140L; BCL11A; JAK2; BHLHE41; NR1H3; RBBP8; NR0B1; EGR3; TRIM22; ZBTB16; HOXB6; HOXB2; KLF5; TFAP2C; MEIS1
Down-regulation	167	SMARCE1; ZNF532; MED13; ZNF83; SPEN; ZNF721; PMF1; ZNF160; NKX3-1; PRDM10; GTF2IRD1; KDM5B; BAZ2A; RAN; NCOR2; CCNC; L3MBTL1; ZNF692; MYT1; CHD8; ZNF248; BPTF; SALL2; ZMYM2; ZNF292; BAZ1B; SOX4; CERS4; SOX2; ZNF44; DRAP1; CUX1; KMT2A; RNF111; KLF10; TCEB2; CHD7; ADNP; NFE2L1; NUP62; XRCC6; SOX11; ZNF611; CCNA2; SMAD7; ID2; KDM2A; CNOT2; RBBP4; USP22; APBB1; HIPK2; NFATC3; NCOR1; VEZF1; ZNF426; ZNF665; SOX12; PQBP1; BASP1; DDX17; NEDD8; RBM14; NLK; ZBTB20; DDX5; PRKDC; SATB2; HCFC2; ZNF432; OLIG2; FLNA; TCF20; FOXF1; UBTF; ATF7IP; TCF12; HEY1; RLF; PHF20; CARM1; ZKSCAN7; PRRX2; HMBOX1; SCAND1; CAMTA1; PITX2; VGLL4; ZNF131; FOXO3; PATZ1; TLE1; NKX2-2; CHD1; ZNF337; TFEC; SMARCA5; KMT2B; ZNF43; APEX1; COPS5; PKNOX2; MAGED1; CREB5; ZNF302; ARID4B; MAF; SIX1; E2F5; SCMH1; SMARCB1; SOX15; FOXG1; EZH2; EDF1; ZMYND8; RBPJ; SFPQ; ASCL1; TBL1XR1; BIRC2; CALR; TRIM28; ING3; TCF4; SIRT2; RUVBL2; BACH2; ARID1A; YBX1; ATF4; JARID2; SIM2; HSF2; TLE4; RXRA; NCOA2; HMGB1; ABL1; EYA1; PUF60; SUZ12; HDAC9; HDAC6; SMARCA4; TP63; TGFB1; SMAD2; FOXO1; POU2AF1; CARHSP1; PBX3; SOX10; TOX; ID3; NFIB; ERBB2; ZEB2; MYRF; HOXC10; PCGF2; SMAD1; MNAT1; HMGN3; EMX2; KDM5D; ID1