Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57649	Cyclopamine	GSE92742	NEU	Human	24h	10uM	EID0316

Response Information :

Types	Number	Response transcription factors
Up-regulation	64	NFKBIA; ECD; MAX; SP100; SOX2; ZNF593; CERS4; LIMD1; SND1; TBPL1; MED23; PIR; ALX1; NCOR2; OSR2; AIP; ZNF263; NCOA4; SUB1; POU2F1; MITF; FOXO3; PDLIM1; BTG1; SMARCC1; MAFB; CTNNB1; ZBTB20; ZBTB24; HDAC1; GTF3A; CARHSP1; TLE4; ESR1; LMCD1; CENPF; SNAI2; MYRF; CREB3L1; TCEB2; TRIM16; ETV5; FOXA2; BRD2; NONO; CITED2; TADA3; TBL1XR1; ZNF394; MNDA; NCOA6; HHEX; HSF2; EMX2; PEG3; MXI1; ARID1A; ZBTB18; PCGF2; KLF6; BHLHE41; NFYC; FOXN3; IRF8
Down-regulation	74	NPAT; ATF5; VEZF1; EGR4; KDM5B; BPTF; E2F8; ZNF107; BRIP1; NKX2-2; ZNF253; E2F3; ZNF217; URI1; GTF2IRD1; KLF9; BANP; FOXG1; SMAD5; FOXC1; CRYM; TCFL5; PRRX2; CREB1; BARX1; TAF9; FOXF1; TOB1; DACH1; RBL2; ZBED1; LHX3; HES1; CCNE1; LEF1; HOXD1; TXNIP; TGFB1; DEK; NFYB; PAX6; SMAD7; ZNF117; SIX1; AEBP1; NR2F6; DLX2; TAF9B; TP63; ZNF131; ZSCAN18; HOXC10; MYBL1; GLI2; CCNH; SHOX2; ID3; ZNF165; SOX13; HDAC9; ETS2; KLF2; ARID4B; PAWR; ZBTB38; ERBB4; ERG; RFX5; MNAT1; MECOM; PHF20; TCF4; ST18; VPS72