Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57646	Sitagliptin	GSE92742	NEU	Human	24h	10uM	EID0315

Response Information :

Types	Number	Response transcription factors
Up-regulation	114	MYB; IFI16; NR2C1; NR1H2; FHL2; TRIP6; ZNF264; SMAD5; RNF111; MED17; ZNF224; EHF; ADNP; ETV1; NKX3-1; RRN3; ZNF12; CHD4; NFKB2; MAML1; NR4A1; EWSR1; ERCC3; TRIM29; FOXA2; XRCC6; SP3; SSX1; RERE; MNDA; PIAS1; MBD4; TRRAP; PBXIP1; PITX1; RAD21; TRIP4; RFX5; PAX6; IRF6; MAGED1; PCGF3; CD3D; BHLHE41; IKBKAP; GRHL2; ZBED2; ZNF202; BCL6; TP63; JAK2; NFE2L2; ZNF44; CALR; TGFB1; TFAP2C; MEF2A; PRDM2; LEF1; TULP3; KDM5D; HIC2; ZNF544; TCF12; ZNF148; ZNF160; ZNF22; KLF10; SOX9; TCF7; HHEX; RBFOX2; SMAD4; SSRP1; HLF; ZBTB16; TCF7L2; EGR3; NAB2; HMGB1; SMAD7; TERF1; RBBP8; CITED1; HBP1; PRRX1; ZBTB18; BBX; JUN; NCOA3; NFE2L3; MLXIP; ZFP36L1; CBX7; UBP1; ZNF217; PCGF2; JUP; ZBTB38; ZNF721; PSMC3; IRF9; ZNF394; TSC22D1; ATF3; ETS1; NR4A2; RXRA; YBX3; GTF2A2; TRPS1; ZFPM2; ESR1; CRK
Down-regulation	94	HMBOX1; EDF1; WNT4; PRDM13; SP140; BATF; BPTF; ASH2L; TCEB2; ZNF467; ZNF688; USF2; GTF3A; TCEA2; ZBTB25; CIZ1; YWHAB; FOXL2; KDM5C; BASP1; ARRB1; NUP62; ZNF552; PA2G4; ELF4; ZNF593; KLF4; GFI1; NKRF; TOB1; HTATIP2; SSBP3; ZNF281; KAT6B; SMAD2; POU4F1; ING2; SP110; ZNF528; CHD3; NR1I2; MYCN; PRKDC; MDM2; PDLIM1; KAT6A; MYCBP; HOXA11; AIP; LITAF; NEDD8; CTBP1; ZNF131; PLAGL1; DDX5; MYRF; FOXC1; YEATS4; BRPF1; BLM; TLE4; ERBB2; CDYL; WWC1; SMAD1; SMAD3; IL16; MEOX1; PURA; JUND; HOXC10; ZNF589; LMCD1; NFATC4; KLF6; KDM2A; TAF10; RBPJ; MYBL1; BHLHE40; DNMT3B; PBX1; CITED2; HOXB7; NFATC3; HOXB6; MECOM; PBX3; HOXC6; MSX1; CCNA2; PAX8; CEBPA; NFKBIB