Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57641	Biib-021	GSE92742	NEU	Human	24h	10uM	EID0315

Response Information :

Types	Number	Response transcription factors
Up-regulation	246	MNAT1; XBP1; JUNB; TFCP2; HOXA2; BCL11B; ZNF571; ZBTB39; GATA6; SSBP3; HES1; ERBB4; HOXA1; NR0B1; NPM1; MED21; IFI16; TBX1; ATF3; TAF7; NR1H3; MNDA; NFYA; BHLHE41; SIX1; BRF2; ZNF394; IRF2; GTF2I; RNF6; EHF; PCGF1; CREG1; SKIL; ANKRD1; SUPT3H; RUNX2; SP140; HNF4G; ZNF225; TAF4B; NR4A2; ATF5; ZIC3; PCBD1; ZNF391; ZNF195; TAF1C; POU4F1; YEATS4; TAF4; NFE2L2; ZNF695; ZNF557; BAZ1B; WHSC1L1; ZNF770; ZNF215; ZNF350; BTG1; ZFP69B; REL; HOXD11; SOX18; HOXC4; MAFB; BMI1; KLF13; LHX6; BCL11A; DLX4; BACH1; EGR1; NFKBIA; CDK2; ZNF235; ASH2L; POU2AF1; TGS1; CREBZF; ZNF254; THAP10; SUPT7L; CD3D; ZNF493; RSF1; SRF; HOXC13; HOXA4; E2F8; FOXA1; NEUROD1; NFYB; SLC2A4RG; PRDM1; IRF4; HDAC9; KLF4; SUV39H2; ZNF141; PIR; ZSCAN31; KLF2; CEBPZ; ZNF184; MEOX1; KLF10; MED17; KLF9; ZNF345; FOXE1; ZNF14; WT1; CCNH; TGFB1; FLI1; FOS; TAF9B; ERF; CBX4; RBL2; TOB1; TFAP2C; TFEC; IKBKAP; FOSB; MAML1; MED12; DNAJC2; CENPF; JUN; CBX7; MNX1; TAF5L; TDRD3; RELA; TRIP11; TBX21; TFAP2A; TEAD4; HIVEP1; PPP1R13L; ZNF529; RARA; ZNF107; GCFC2; EYA2; ACTL6A; NR1D2; ZNF117; ARRB1; URI1; KLF3; PRMT2; BCLAF1; EGR4; DBP; ZNF124; CERS6; JUP; NAB2; SP140L; ZNF12; SKI; IRF6; HDAC6; CREB1; TP63; NR1H2; ETV1; TLE2; HOXB13; FOXL2; CEBPG; CBFA2T2; HOXC10; JAK2; SOX13; TRIM22; KLF11; CREBL2; TRAF6; ZNF304; HTATIP2; ZNF354A; HOXA5; ESR1; PLAGL2; CREB3L1; PGR; CNOT6; SMAD7; PNRC1; MEF2D; NR5A2; KLF5; ELF3; HOXB2; TAL1; STAT6; SMARCA1; ATF7IP; MYCL; ST18; SPDEF; ZSCAN18; MED6; RFX5; NCOA1; ZFPM2; BNC2; NR4A3; EGR2; ADNP2; MYBL1; IRF1; REST; IRF9; YAP1; RREB1; ZMYND8; KDM4C; FOXF2; DLX2; MXI1; DDIT3; CEBPD; SOX17; OVOL2; SERTAD2; ZNF266; BAZ1A; GRHL2; SNAI2; KLF6; ZKSCAN1; TSC22D1; NAB1; HOXB7; ETS1; TXNIP; LMCD1; MED24; ASCL1; TOX3; MECOM
Down-regulation	266	TLE1; MTF2; HDAC2; DRAP1; SMARCA4; CXXC1; SATB1; SPEN; ESRRG; CHD8; TCEB2; CARM1; EZH2; TLE4; THAP4; TCF4; HNRNPD; RBPJ; MAZ; HSF2; GMEB2; GMEB1; ZNF358; RUVBL2; NUP62; ZNF211; ZNF292; HMGB3; ZBED1; PITX2; RLF; RBBP4; DR1; SAP30; FOXO3; ZBTB17; SOX2; PMF1; CARHSP1; ZNF688; UBE2I; E4F1; BIRC2; RUVBL1; KMT2B; BASP1; MNT; KAT5; MBD3; ZNF143; MDM2; BRPF1; MAFG; RFC1; RNF10; TCFL5; ZNF226; USF2; ZMIZ2; PHOX2B; MED23; ZMIZ1; WDR77; PHF20; ZNF410; TRIM28; KMT2A; HNF1A; DPF2; TBL1X; EDF1; BRD8; APBB1; ENO1; ZHX3; SREBF1; PA2G4; ZNF721; ZFHX4; TFEB; ZNF593; XRCC6; PPARGC1A; ZNF281; USP21; BRD3; CCNC; TBP; POU3F2; PSIP1; HEY2; GON4L; ZNF672; MYCBP; VEZF1; HDGF; FOXJ1; CHD4; ZBED2; DACH1; FUBP1; NKX3-2; KMT2D; HMG20A; MKL1; FOXJ3; PIAS3; MTF1; NFAT5; HCFC2; ZNF160; ZNF24; INSR; CSDE1; SAFB; RNF111; ING1; MYB; ZNF629; ZNF468; SOX11; ZNF8; NRBF2; UBE3A; WHSC1; ARNTL; SAFB2; KAT6B; SCAND1; SMARCC1; ASXL1; SETDB1; NEDD8; ARID3B; KDM4A; ATF4; PRRX2; POU5F1B; ZNF787; PQBP1; PHF2; NFIX; RB1; NPAS2; CTR9; TAF12; SMAD1; ZNF665; ZBTB32; PLAGL1; RXRG; ZNF532; NR2F2; BTAF1; ZNF432; EYA1; HIPK2; LMO1; TRIM25; HMGN3; ZNF587; TBX3; JARID2; E2F3; MED13; CHD1; ZBTB18; RBBP7; POU2F2; KDM5B; TCF12; MYRF; LITAF; SP110; YBX1; RYBP; CBX3; CNBP; ZNF835; BANP; SMARCD3; POLR2A; SMARCA5; ZNF646; CASZ1; NELFB; HMGXB4; MYC; HDAC7; SND1; CERS4; NCOA6; ZNF22; ZNF423; TCF15; SUPT5H; TBX2; ISL1; GTF2A2; JUND; FLNA; ABL1; NCOA4; ZEB2; TSC22D2; ID3; MITF; ENY2; SMARCE1; SMAD4; DNMT3B; PATZ1; ZFP36L2; ATF2; CHD9; ZNF611; PHF1; HLF; ZNF654; HIRA; ING2; SIRT2; HEY1; ID4; SOX10; PBX3; ZNF580; PCGF2; NFE2; ZNF711; PEG3; MEOX2; CUX2; EMX2; ERG; MAGED1; ZFP36L1; CDK7; TFCP2L1; SALL2; NR2F1; E2F5; ZEB1; COPS5; SOX9; TADA3; ELF5; CCNA2; SSBP2; NCOR2; MYT1L; KDM2A; MEIS1; TAF1D; VGLL4; CHD7; NANOG; CRYM; ZMYM2; BHLHE40; TAF10; STAT5B; NFATC3; NFATC4; FOXO4; ID1