Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57631	Motesanib	GSE92742	NEU	Human	24h	10uM	EID0315

Response Information :

Types	Number	Response transcription factors
Up-regulation	140	PPARD; XBP1; ZNF652; FHL2; MED23; IFI16; WNT4; ZNF195; TBX3; ETV5; BHLHE41; ZNF623; PAXBP1; ELK3; MITF; MGA; HOXA10; HDAC4; TP53; SP100; ZSCAN18; ATF5; ZNF136; SKI; HOXA11; BNC2; ANKRD1; ZNF274; ASH2L; PEX14; CREM; TAF11; TBX1; TEAD1; RERE; PCGF2; ZNF516; ELF3; ZBTB38; TCERG1; PLAG1; BAZ1B; TCF7L1; TRIP4; NFE2L2; MKL2; LEF1; NR3C2; HOXC4; CTCF; MAFF; PPP1R13L; SMARCA1; CBX6; AR; NFKBIA; IRF6; ZNF124; CBFB; ESR1; ZSCAN31; RFX5; EHF; IKBKAP; THAP10; PCBD1; POU2AF1; MYCL; TCF12; HOXC10; JUP; PTRF; ZNF44; ZNF264; NR2E1; REL; TGFB1I1; TULP3; NR4A1; TRIP6; STAT1; AFF1; SOX13; EGR2; E2F8; MLXIP; ZNF654; TAF1D; RBFOX2; OSR2; EMX2; ACTL6A; CBX7; PURA; JUN; GRHL2; KLF6; TBL1XR1; IRF4; ZNF107; PEG3; HTATIP2; LOXL2; NFATC3; ITGB3BP; PGR; SMAD1; RREB1; ZNF394; SALL1; ZBTB20; HEY1; MSX1; SHOX2; ID4; PITX1; RBPJ; ASCL1; NFE2L3; HLF; SNAI2; PHIP; PRRX1; CUX1; ZFP36L1; SPDEF; BRD2; WWTR1; ISL1; FOSB; NKX3-1; HDAC9; ATF3; PBX1; MED24; TOX3; TWIST1; ID1; KAT6A; CRK
Down-regulation	94	ESRRG; NUP62; GTF3A; BTF3; BASP1; CXXC1; NHLH2; MAZ; UBE2B; ARID3A; CIZ1; FHL5; LPIN2; TRIM33; SP110; HDGF; PIAS2; MDFI; TCEB2; ZNF200; ARID4B; MAX; MXD4; ZNF688; MYRF; TLE1; ZNF510; ZNF410; NEUROG1; USP21; ZBED1; ZBTB18; EDF1; KMT2B; KLF5; CHAF1B; ATF7IP; ZNF165; POU3F2; MYB; TGFB1; SUZ12; LDB1; PBX3; ASXL1; TRIM25; KAT2B; SCAND1; MTDH; KMT2D; DR1; LIMD1; GFI1; PHF20; DNMT3B; PDLIM1; NEDD8; MED13; CDK7; ING2; ADNP2; FUBP1; ZNF281; HMGN3; SSBP2; CHD1; FOXC1; NPAS2; BRD3; ENY2; KDM5B; MYT1L; ETS2; PNRC1; BAZ2A; CCNE1; ZNF589; INSR; NFE2; TOB1; SMARCD3; SMAD3; ZEB2; BHLHE40; WT1; HOXD1; VPS72; MEIS1; HOXB6; TSC22D1; CCNA2; CITED2; STAT5B; NFKBIB