Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57628	Afatinib	GSE92742	NEU	Human	24h	10uM	EID0315

Response Information :

Types	Number	Response transcription factors
Up-regulation	127	ERBB4; FOS; ASH2L; TRIM24; XBP1; NR0B1; ZNF184; STAT2; ZMIZ2; TRIP6; RORA; KLF10; PCGF1; TBX1; CEBPG; IRF4; CDYL; ZNF107; TULP4; BHLHE41; MED20; ZNF250; BRF2; FOXA1; WWC1; RNF6; ZNF394; ZNF195; TRIP11; E2F3; HTATIP2; ZBTB16; KLF13; ZNF14; STAT4; RNF10; TAF11; TRIM22; TADA3; CBX3; ECD; RELA; NFIC; SREBF2; ZNF350; ATF4; PRDM1; ENO1; RREB1; NR1H2; FOXM1; MED17; FOXF2; MNDA; NKX3-1; HOXB13; BCL11B; TRIM16; STAT1; DNAJC1; RUNX1; TTF2; GTF3A; RFX5; NFE2L2; JUN; KLF11; TSC22D3; CEBPB; NKX2-1; MYBL1; ZNF304; SERTAD2; ARNTL2; E2F8; ID2; MAFB; RERE; CDK2; MITF; DAXX; MED6; RUNX3; ZNF146; CRYM; ZNF85; SLC2A4RG; HIVEP1; EHF; CBX7; TP63; ZBTB18; KAT2B; ELF5; FOXJ3; IL16; TGIF1; ZBED4; NFE2L3; SOX17; DEK; RBBP8; TGFB1; POU2AF1; KLF6; ELF1; IRF6; UBP1; SIAH2; RXRA; OSR2; TFEC; ID1; YBX3; HDAC9; IRF1; ZHX2; NFATC3; EGR2; MSX1; FOSL2; MLXIP; LMCD1; SOX10; ETS1; ASCL1; CRK
Down-regulation	173	MTF2; ZNF91; MAZ; TCEB2; NRIP1; SATB1; LEF1; ZFHX4; TSC22D2; TCF4; FUBP1; HDAC1; CHD8; HSF2; MED13; MED23; CLOCK; UBE2I; PRKDC; SMAD5; ZNF226; KMT2D; HR; ZNF292; KMT2A; TLE1; NR2F2; E4F1; CHD4; MED12; PLAG1; RBBP7; MYCBP; NUP62; HMG20A; SMARCC1; RNF111; KAT7; ZBTB7A; TEAD1; CBX5; CARM1; TGIF2; SMAD6; ETS2; RBBP4; BRD8; CDX1; ZBTB20; CHD1; SUZ12; NR3C2; HOXC4; SOX9; BCL3; PLAGL1; ZNF593; LITAF; ZNF688; SSX1; INSM1; CITED1; ZNF665; POU3F2; GATA6; ZNF652; NR2E1; ING3; CHD9; SFPQ; RFC1; FOXN2; TCF7L2; ZNF131; GTF2IRD1; ZNF587; KAT6A; E2F5; ZNF721; NRF1; RXRG; DR1; LOXL2; ARRB1; TBPL1; ZNF205; ARNTL; EDF1; MTF1; KLF4; MYRF; WT1; DMTF1; RNF141; CCNT1; DLX2; NR1H3; HHEX; PDLIM1; BTAF1; SMAD1; DACH1; ZNF432; BBX; AHR; ERG; THAP11; FOXO3; ZSCAN18; TOX; BCL10; TCF7; ST18; PEG3; ZNF532; MED1; ING2; SMARCC2; EYA1; HMGXB4; CHD7; PURA; CARHSP1; NFAT5; SOX13; ZNF528; PCGF2; ZNF423; PBX1; BAZ2A; HMGA1; MECOM; ZNF165; ZNF160; CCNA2; POU4F1; PROX1; ZFHX3; MEOX2; NEDD8; RUVBL2; NANOG; KLF9; ID4; RCOR3; JUP; SMAD3; FOSB; EMX2; TAF1D; MAF; SCAND1; TOB1; BAZ2B; FOXF1; HMGB2; BHLHE40; ESR1; SATB2; TWIST1; HOXB7; NFATC4; CALR; HOXC6; ZNF331; HMGA2; PBX3; HMGN3; FOXO4; PAX8; NFKBIB; BASP1; CEBPA