Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57603	Cyclopamine	GSE92742	NEU	Human	24h	10uM	EID0315

Response Information :

Types	Number	Response transcription factors
Up-regulation	108	XBP1; GATA2; BAZ1B; IFI16; THAP1; BCL11A; ZSCAN31; NFE2L1; ZNF430; NPM1; ETS2; MAX; ZZZ3; ETV1; PBXIP1; PTTG1; BMI1; ZNF124; MED17; ILF2; NR4A1; NFX1; MITF; GATA6; AR; IKBKAP; ZNF652; PCBD1; ZNF107; RBBP8; TRIM16; YAP1; ACTL6A; PIR; FOXA2; TBX3; SP100; BNC2; ITGB3BP; TTF1; SMAD4; NFE2L2; SP140L; CTR9; TRRAP; BCLAF1; FOXN3; NFKBIA; TXNIP; TAF7; ZNF12; E2F8; NR4A3; ZNF394; STAT6; HTATIP2; FOXL2; ARNTL2; MED6; JUNB; TAF11; THAP10; TCF21; NKX2-1; CREB3L2; TRIM22; ATF5; STAT1; PRMT2; PGR; AES; SMARCA1; ISL1; CDK9; BHLHE41; CREB1; JUN; PITX1; CITED1; MAFF; MYC; ZBTB16; NR3C2; ATF3; WWTR1; REPIN1; FOSB; ARID5B; IRF9; ID3; COPS2; TDP2; TCF12; SNAI2; MNDA; PRRX1; HLF; HOXC6; RBPMS; POU2AF1; ZFPM2; HLX; HOXB7; ID4; MSX1; ID1; MAGED1; CRK
Down-regulation	143	TLE1; MTA1; GATA1; SPEN; CARM1; TCEB2; LHX2; SATB1; ARID3A; KLF1; ERBB4; PA2G4; INSR; RUNX3; ESRRG; MAZ; ZNF281; CBX5; FOXJ1; E4F1; BASP1; ZNF688; MAFB; ZNF423; BRD4; NUP62; ARID5A; MYCN; ZNF83; RNF141; LHX6; KMT2B; SHOX; ZNF580; KAT2B; ETV6; TADA2A; ARID3B; ZIC3; PHF20; JARID2; GTF3A; MAFG; ZNF165; PRRX2; CHD1; CHD4; ZMIZ2; HMBOX1; DDX17; MTDH; ZNF324; TFEB; DACH1; TCF3; TCF20; ZNF573; POU3F2; ELF4; MNT; KDM5B; BCL3; FOXK2; RLF; BRD8; HIPK2; TOB1; HIC2; ZNF646; KLF13; CRYM; OLIG2; ZMYM2; ZMYND8; HOXD1; MYRF; PDLIM1; CNOT2; BCL11B; TFCP2L1; SERTAD2; MKL2; SOHLH2; IRF7; ZNF562; SALL2; ERBB2; SMARCA5; MEOX1; RNF10; ZNF711; TCF7; MYB; BAZ2B; CDYL; CBX6; RBPJ; HMGB3; BRD2; NANOG; FOXC1; SMARCE1; PATZ1; ZNF589; E2F5; KDM5D; BTAF1; NFATC4; BAZ2A; ZBTB18; FUBP1; NFATC3; TAF10; HOXC10; SMAD1; ZNF217; PCGF3; VDR; ING2; ARID1A; YBX1; SSBP2; SATB2; CHD7; LOXL2; TOX; YBX3; BATF3; NFE2; RXRA; NKX2-2; TAF1D; CUX1; ZFP36L2; TWIST1; NFAT5; ZNF721; SCAND1; ERG; MAF; SMAD3; TRPS1; CEBPA