Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57599	Sitagliptin	GSE92742	HA1E	Human	6h	10uM	EID0314

Response Information :

Types	Number	Response transcription factors
Up-regulation	139	ZNF195; CDK2; ZNF274; ECD; TERF2; ZNF34; KAT2B; ZNF281; ZKSCAN3; SAP30; ZBTB40; ZNF85; ZBTB11; ARID3A; ITGB3BP; ZNF337; PSPC1; PMS1; ARID5B; CCNH; TBX21; ZNF84; PIAS1; RLF; ZMYND11; CITED2; COPS5; IKZF1; ZNF239; NKRF; PAX5; ZNF217; SUMO1; ZNF532; MYBL1; NR4A2; CEBPB; CTBP2; LITAF; SP140L; RNF6; TAF5L; NPM1; KLF13; PRRX1; CEBPA; CBX7; GTF2A2; MXI1; ZNF544; INSR; EN1; ZNF573; NFE2; NFE2L3; NONO; IFI16; FOXO1; TOB1; ZNF91; ZBTB18; ETS1; ELF2; SPEN; UBE2B; ESRRG; ZNF140; SP3; ZNF586; SMARCA1; ZNF331; RBM39; NR2C1; IRF9; TRPS1; TRIP4; HOXB6; HOXD1; MAML1; BCLAF1; TRIM22; HMGN3; ZZZ3; ZNF432; HBP1; CRYM; TCF7; ZNF32; ZNF665; CDK7; HOXB7; HOXB2; FUBP1; PHF20; HTATIP2; RFX5; HMGB3; ZKSCAN1; ZNF124; HIC2; ZNF146; PHIP; RHOA; BRD2; MNDA; CALR; ZMIZ1; BRD8; ZMYND8; BRD4; ZNF232; CENPF; IKBKAP; CDC5L; PSIP1; VPS72; ZNF354A; TRIM32; MGA; ZSCAN18; HDAC2; BNC2; ZNF117; MTF2; MED17; ESR1; HOXB5; BASP1; APEX1; TRIB3; MYRF; HHEX; RAN; LOXL2; ILF2; ZNF589; YBX3; DEK; TULP3
Down-regulation	105	TP53; SMARCA4; SOX15; GATAD2A; NFKB1; TRRAP; CIZ1; TCF21; PRDM8; SMARCD2; KMT2A; NR2F6; ZNF787; WDHD1; MAZ; ZNF512B; ZBTB20; UBE2I; CAPN15; ELK1; CITED1; POU3F1; FOXG1; EZH2; HLTF; WHSC1; KDM2A; RBM14; AEBP1; TCF7L1; USF2; HEY1; PIAS2; RUNX1; EGR4; NUP62; TBL1X; BRCA1; SUV39H1; POLR2A; NR2F1; KDM5B; POU3F2; YBX2; SIX1; PPARGC1A; ZNF629; SIX3; CARM1; NELFB; NFE2L2; NKX2-2; MAFB; MAF; FOXF1; LZTS1; ZNF768; PPRC1; NKX3-1; OVOL2; TLE2; CDK8; ADNP2; MBD2; ZHX2; TSC22D2; KLF6; BHLHE41; IRF4; KDM5D; E2F3; BCL11B; IFNB1; ASCL1; MXD1; ELF5; FOSL1; JARID2; DLX2; FLNA; ZBED2; IRX5; TFDP2; STAT5B; TSC22D1; MEOX2; ISL1; WWTR1; ZNF267; NRIP1; SOX11; ZFHX4; POU2AF1; TRIM33; ETV1; EED; FOS; WWP1; NR1H2; GATA3; PPARD; DACH1; MAGED1; FOXO3; PPARG