Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57595	Amonafide	GSE92742	HA1E	Human	6h	10uM	EID0314

Response Information :

Types	Number	Response transcription factors
Up-regulation	139	AHR; NR1H4; PNRC1; TOX; MYBL1; CALCOCO1; KLF11; NCOA3; SUMO1; FOXN3; CCNC; SHOX2; EN1; MED14; ZNF623; ETS1; ZFPM2; COPS5; DDIT3; BAZ1A; RLF; E2F8; NHLH2; MYCL; CHD4; TTF2; ZNF573; INSR; SOHLH2; HLF; SPDEF; FOXG1; TAL1; SPIB; ENY2; IFI16; IKZF1; FLI1; RNF138; BAZ2A; NFKB2; TWIST1; LMCD1; TOX3; GTF2A2; TRIM22; UBE2B; KLF7; HOXD1; BCL6; VPS72; ST18; SUPT5H; PDLIM1; NKRF; ZNF354A; RBBP8; ERBB4; TERF1; ACTL6A; RB1; INSM1; IRF9; ZNF74; SAP30; NR0B2; IRF6; TAF11; PROX1; SSX1; RYBP; PAX5; ZNF410; ATF5; STAT1; NFE2L1; BACH2; SUZ12; NFE2L2; HIRA; CAMTA1; CDC5L; YEATS2; TP63; KLF13; ZNF232; TFAM; ZNF281; CEBPD; RAD21; SIX6; NRIP1; TBPL1; HOXB7; CREB1; RORA; STAT4; ZNF423; NFE2; SIX1; BHLHE41; BIRC2; ELK3; ZNF12; TCF7; HDAC2; POU2AF1; ZMIZ1; MED17; GATA6; TCEA1; NFATC4; CDK7; HOXB6; SPEN; ZNF22; TLE4; PFDN5; TRIM29; XRCC6; ILF2; ZFHX4; RUNX3; TRIB3; MEIS2; LEF1; CRY1; RAN; PEG3; LOXL2; PSIP1; CHD8; DEK; YBX3; PBX3; HOXB2; TULP3; MYRF; BASP1
Down-regulation	179	GABPB1; TP53; MTA2; TGFB1I1; HMG20B; TRIM16; FOSB; ZNF580; TRIM28; ELF3; DDX54; ZNF614; NFX1; MSX1; HMGA2; RBPMS; TRIP6; TCERG1; PITX1; ARHGAP35; LMX1B; FOXL2; ERBB2; CENPB; RFX5; ZNF211; NCOR2; MYCBP; SATB2; PURA; MLX; DLX5; CREB3L2; SUV39H1; PIAS3; RBM14; ESR1; USF2; PRMT2; ADNP; ELK1; PAX8; DNAJC1; SIAH2; ZHX3; KLF2; ZNF764; KDM2A; ZNF134; SOX12; EYA2; ZNF532; TEAD1; BHLHE40; SLC2A4RG; MXD4; MKL2; ID1; REPIN1; SMARCD2; ZNF552; ZNF226; HOXA1; PQBP1; ID2; SMAD6; ZNF587; SOX17; NR4A2; FOXF1; ZSCAN31; MAFB; AFF1; TLE2; ETS2; NR3C1; BARX2; TRIM25; HDAC4; ZNF419; ZNF606; ZNF512B; POLR2A; PIR; ZFP64; ZNF629; OLIG2; MAF; SMARCA2; IRX5; RREB1; FOXC1; GTF2I; KLF5; CLOCK; SOX13; MECP2; PCGF2; KDM5D; NKX2-2; IKZF5; ZMIZ2; MXD1; LIMD1; WNT4; RNF141; ZNF274; ELF1; CREBZF; CHD7; LPIN2; CUX1; CNOT3; ZNF586; CTNNB1; SCAND1; TSC22D4; FOSL1; HOXA11; KAT6B; NELFB; ZMYM2; NR2F2; HDAC9; NR2F1; SFMBT1; TSC22D1; DBP; KDM4A; DEAF1; SMARCA4; CEBPA; GTF2IRD1; E2F2; FOS; BCL3; ZNF329; MECOM; TFAP2C; STAT5B; KAT7; TDP2; EHF; LZTS1; EYA1; GRHL2; CHD9; FLNA; EDF1; NR3C2; SREBF1; MEIS1; TFEC; NFYC; ISL1; GATA2; GATA3; NCOA1; SKI; JUP; MLXIP; HOXC6; NCOA2; ID4; NKX3-1; RFXANK; TGIF1; OSR2; KLF6; JAK2; TXNIP; CREG1; ZNF589; ADRB2; PPARG; FOXO3; MYB; NFKBIA; EGR3