Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57579	Afatinib	GSE92742	HA1E	Human	6h	10uM	EID0314

Response Information :

Types	Number	Response transcription factors
Up-regulation	179	ZFP36L2; DDIT3; PBXIP1; KLF11; FLI1; INSR; ZNF195; MYBL1; AEBP1; KDM5C; ZFPM2; FOXE1; ST18; SETDB1; NR4A3; ZNF85; IRF6; ERBB4; ETS1; PBX1; TAL1; IRF9; FOXF2; ZNF117; ZNF43; CALCOCO1; ZNF665; ZNF544; MEF2C; FOXN3; SALL2; TOX; CDIP1; BNC2; ZNF394; CNOT2; NR1H4; SUMO1; SPDEF; AR; HHEX; POLR3C; NOC2L; PBX3; CEBPD; ZNF91; ZNF350; PSMC3; CCNH; ING4; ZNF239; ZNF532; ZNF688; PAWR; THAP7; FOXA1; NFIX; CCNT1; ZNF74; TTF2; PCGF3; ZSCAN18; E2F8; GATA6; ZNF124; ZNF623; ZNF93; ZNF444; ZNF232; CERS6; HOXB1; ELF2; BNC1; HBP1; NFATC4; TAF1; ZMIZ1; IFI16; MYCL; DMTF1; SOX13; ZNF354A; TCF7L2; NFATC3; TEAD4; HOXD1; ZNF671; NFE2; CBFA2T3; CDK2; ZNF84; LMCD1; ZNF83; HOXD11; CTBP1; SPIB; POU2AF1; PHIP; ARL2BP; NR0B1; ZNF273; HIC2; TAF7; VPS72; SUB1; CEBPA; SOX2; PFDN5; ZNF331; TFAP2A; ATF4; ZNF692; TBX3; TCF4; ZNF268; ZNF586; EPAS1; ZNF573; CEBPB; CBX4; TCEA1; YAP1; CITED2; RAD21; LYL1; CERS4; ZBED1; ILF2; SRCAP; PLAG1; FOS; NCOA3; IKZF1; PAX5; ZNF432; KLF1; AHR; ZNF140; ZNF415; SOX11; GTF2A2; TFAP2C; ZNF266; RNF138; NKX2-1; ATF3; TSC22D3; KLF13; CHD9; CHD8; ZMYND8; HIRA; ZNF32; JUND; KLF7; BIRC2; MED17; PEG3; TLE4; ID3; ZNF589; ID1; TULP3; FOXO1; TRIB3; MEIS2; ZNF12; HOXB2; BRD4; TOX3; ZEB1; MTF2; JUP; ATF5; KLF3; LOXL2; RBBP8; PAX6; TXNIP
Down-regulation	173	CTR9; MLX; GABPB1; KDM2A; HNRNPD; MSX1; ERBB2; RBM14; ZBTB20; NUP62; NFKB1; TRRAP; TP53; KLF2; RELA; NCOR2; YBX1; MAFB; TCERG1; MTA2; KMT2A; ZIC1; TAF10; ORC2; SUV39H1; DLX4; DDX54; NFE2L3; PIAS3; RFX5; CCNA2; MTA1; KDM5D; ENO1; LPIN2; NRBF2; CDK8; PIAS2; ATF1; TRIM28; CHD3; SMAD7; ELK1; MAF; AATF; BHLHE40; MEN1; RBBP5; ZNF516; FOXJ3; NR1I2; EBF2; SF1; HDAC6; SNIP1; ZNF148; ID2; TBP; JARID2; GATAD2A; HOXB13; BLZF1; USF2; POLR2A; TEAD1; TSC22D2; HMGA2; BMI1; YWHAB; BATF3; TRIP6; HLTF; SND1; EGR4; NKX3-1; MYCBP; SP140; EGR3; HOXC6; ZNF226; RBPMS; BAZ1B; SATB2; UBP1; HDAC4; MBD2; ZMIZ2; BAZ1A; SFPQ; SNAI2; SIM2; EP400; PITX1; SMARCA4; NELFB; E2F3; MED1; NR1D2; FHL2; NFATC1; MYCN; TFE3; EGR2; BRPF1; RNF141; SMAD2; HOXA10; PDLIM1; RBBP7; TOPORS; NR2F1; STAT5A; ETS2; SMARCA2; ZBTB25; ZFHX4; CDYL; REPIN1; FOSB; ZNF652; TBL1X; FOXO4; FLNA; ZMYM2; EDF1; EMX2; PATZ1; HSF2; MECOM; SIX1; SAFB2; CREBZF; LZTS1; HOXB7; NFAT5; CREB1; DACH1; KDM4A; MAFG; RCOR1; THAP1; EYA1; DPF2; HEY2; HDAC1; NFKBIA; CREG1; CBX3; EED; NR2F2; NFYC; MED24; BBX; ZNF267; TSC22D1; IRX5; ZNF329; NR1H2; TRIM29; KLF4; BCL11B; ARID4B; CRY1; EHF; STAT5B; HOXA5; PPARG; GATA3; ELF5; BCL3; TFDP2; DAXX; MYB