Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57567	Cyclopamine	GSE92742	HA1E	Human	6h	10uM	EID0314

Response Information :

Types	Number	Response transcription factors
Up-regulation	216	TCF21; AEBP1; AR; TCF3; CDIP1; ST18; TOX; L3MBTL1; NFIX; ZNF562; PNRC1; NR1H4; ZNF345; ZNF623; SUMO1; FOXF1; HIPK2; SCAI; BNC1; ZNF85; CBFA2T3; ZNF675; ZNF10; YEATS4; SUPT3H; PAWR; MED21; ZNF225; TTF2; HLX; ZNF155; ZSCAN9; ZNF254; CCNH; FOXA1; MED25; POU6F2; ERBB4; ZNF117; KAT2B; PROX1; TBX2; SPDEF; ZNF667; CHD4; ZNF573; IRF6; MAML3; CEBPD; ZNF34; ZNF81; ZNF682; ZNF83; TAF12; HMBOX1; MED14; PAX5; ZNF195; ID1; SPI1; ZFP36L2; TCEA2; KLF9; SATB1; ETS1; ING4; ZNF350; VPS72; ZSCAN18; PRDM12; SKIL; INSM1; THAP9; MYCL; POU1F1; BCL11A; CUX2; ZNF43; ZNF91; CDX1; CREBL2; MYBL1; NR4A3; NHLH2; RBL2; SRY; TBX1; ZNF214; ZNF674; ZFPM2; ZNF273; ZNF257; FLI1; ZNF234; EGR4; SPIB; BARX1; SOX5; ZNF440; KLF5; TAL1; TRPS1; NFE2; FOXF2; ZNF354A; ARL2BP; SOHLH2; TOX3; KLF7; HOXD1; GATA6; HIRA; NEUROD1; HOXB1; KLF13; PFDN5; ZNF749; POU4F3; YAP1; CREB1; INSR; SOX2; ID3; BRCA2; ZKSCAN4; ZFP69B; FOXG1; DMTF1; TCEB2; PRDM14; CERS6; CAMTA1; HDAC5; ZNF165; ZNF74; NFE2L2; SOX3; NFATC4; ZNF239; IFI16; THAP10; PSMC3IP; ZNF112; ARNTL2; ZFX; IRF9; MEIS1; LEF1; ZNF141; ZNF665; SOX11; NR2F1; ZNF334; ZNF711; HSBP1; TFAP2A; HBP1; ZNF770; HMGN3; ZNF124; NFATC3; ZNF415; RB1; TCEA1; DACH1; TCF7L2; HES1; ZNF544; ZNF654; ZNF264; WT1; JUP; ZNF586; ZNF215; ASCL1; CUX1; NR5A2; NCOA3; EPAS1; ZNF93; LHX3; PBX3; HMGB3; ZNF331; HHEX; NKX2-1; URI1; ZMIZ1; SSBP2; ZKSCAN1; ZNF44; SSX1; MED12; MED17; PBX1; ID4; BNC2; TAF9B; CARF; PEG3; ATF5; TULP3; GTF2A2; ZBED2; ZMYND8; TBX3; ZNF232; FOS; MEIS2; HOXB5; TRIB3; RBBP8; LOXL2; VDR; TCF4; YBX3
Down-regulation	408	TCERG1; GABPB1; NUP62; TP53; SUV39H1; EZH2; KDM2A; CTR9; KAT6A; DDX54; RBM14; ETV5; RELA; FOXJ3; CCNA2; ERBB2; CENPB; TRRAP; SF1; MSX1; TRIP6; PAX8; KDM5A; ELK1; ZNF263; FOSL1; NFKB1; SMAD7; NRF1; TBP; HMG20B; HLTF; CHD3; BRPF1; NFIL3; ZBTB40; BMI1; SNIP1; ASXL1; USF2; KMT2A; TRIM28; MLX; TSC22D2; MTA2; UBE2I; SMARCA2; POLR2A; ORC2; HNRNPD; PIAS3; ZNF783; HMGA1; STAT5A; ZNF672; ZBTB20; ZNF282; HOXC6; BATF3; SAFB2; ZNF148; PHF8; TBL1XR1; MAZ; TFEB; TCF20; TAF1D; ZNF337; RNF111; TRAF6; ZNF212; CALR; CREB3L1; ZBTB24; RELB; SIM2; SP2; MYOG; KAT5; HSF2; CITED1; NCOA4; EP400; NCOR2; FEV; SFPQ; FOSB; ZBTB38; PBRM1; HCFC1; CASZ1; TGFB1I1; SUPT6H; MAFF; TSC22D4; HOXA10; UBP1; SMARCD1; TFE3; ERF; CCDC59; FOSL2; KDM5D; ADNP; ZNF45; FHL2; MED1; HDAC6; RFX5; MTF1; ZKSCAN7; ZNF358; PCGF2; ZNF532; SMARCD2; HOXB7; RBBP5; PAXBP1; NFX1; PPP1R13L; SIAH2; AFF1; CHD1; HOXA5; MTA1; ZNF384; NRBF2; RERE; PLAGL2; MEN1; ZNF512B; NFKBIA; ZMYM2; ATF1; BHLHE40; NKX3-1; ID2; CTNNB1; BAZ1B; DPF2; TBPL1; RREB1; SFMBT1; HDAC7; NELFB; RNF4; SNW1; TAF10; ZNF408; KAT7; NFYC; USP16; SP140; FOXO4; NR1D2; BCL10; GTF2F1; EDF1; HIVEP2; AATF; NFKBIB; EZH1; ZNF473; MED6; USP22; RXRB; BAZ2A; MNX1; MEOX1; TRIM16; LIMD1; MYNN; ETV4; ELF1; KLF2; SMAD2; HMGXB4; ZNF580; ZNF146; NFRKB; TAF6; ZMIZ2; EBF2; IRF1; ARID4B; MSC; ELK3; ZBTB16; ZFP64; BCLAF1; DNAJC2; JARID2; RBPMS; PATZ1; PHF2; BRD3; TGS1; KLF12; HMGA2; ZZZ3; BTG1; CIZ1; ZNF574; CAPN15; HOXA11; PA2G4; MKL1; SMARCC2; ZNF552; DEAF1; CARM1; GATAD2A; REXO4; HOXA1; SP3; TEAD3; BTAF1; NCOA6; FOXC1; FLNA; CDYL; PIAS2; MED23; UBTF; KDM4A; REST; ADNP2; UBE3A; RUNX3; PSPC1; ZNF211; TGFB1; SND1; CTBP1; ZBTB18; JUNB; SMARCA4; ZNF217; DNMT3B; SIN3B; TBL1X; SMARCE1; VGLL4; ERCC3; PUF60; TAF4; PIR; ZNF443; EYA2; POU2F1; CIC; CEBPZ; HMG20A; MAF; NCOA2; EED; SMAD4; STAT6; E2F6; SAP30; HDAC4; TAF5; SETD2; FOXO3; BRD2; ZNF266; PSMD9; BBX; SIX1; ARID1A; ZNF248; SHOX2; SLC2A4RG; BLM; LPIN2; ING3; SREBF1; DR1; XBP1; ZNF274; ABL1; PITX1; ZIC1; CBX3; NR1H2; ZSCAN32; ZNF764; PPRC1; E2F3; ZNF410; GMEB2; AIP; ARID5A; OSR2; ZNF506; KMT5A; ZNF629; REPIN1; ESR1; PMF1; ZNF419; NONO; TRIM27; MECOM; HDAC1; ZNF528; ATN1; CEBPB; ZBTB25; KDM5B; SOX10; VEZF1; RNF6; BCL3; MAX; ETS2; ELF3; LHX2; ZNF324; ZNF652; C1QBP; TRIM32; MGA; USP21; TFAP2C; PRKDC; CHD7; CXXC1; IKZF5; CRY1; SUB1; ENO1; CTCF; UIMC1; CNOT3; ARID3B; NFATC1; EGR2; HOXC10; MTF2; CREBZF; RBBP7; HDAC9; NPAS2; MAFB; ATF4; EGR3; ATF7IP; BATF; ZNF14; CENPF; SPEN; ZXDC; NR3C2; GATA3; ARID4A; DAXX; SSBP3; MED15; KAT6B; CEBPA; ZBTB43; TGIF1; STAT5B; CITED2; MAFG; KLF4; PRPF6; ZNF134; NR2F2; YWHAB; STAT1; ZNF721; CRK; ZNF131; PHF20; IRF4; XRCC6; MYC; SSRP1; ZNF267; FOXO1; TADA3; FOXD1; TFAM; TLE1; NFAT5; TWIST1; SIX2; ADRB2; SMARCD3; BRD8; LZTS1; MED24; ELF5; NFKB2; SOX9; APEX1; MAGED1; TSC22D1; SCAND1; ZNF589; BASP1; MYB; NR1H3; HMGB2; GATA2; PPARG