Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57530	Afatinib	GSE92742	HA1E	Human	6h	10uM	EID0313

Response Information :

Types	Number	Response transcription factors
Up-regulation	120	ZNF273; NFYB; ZNF93; ERBB4; KLF3; ZNF91; TTF2; ZNF141; ZNF107; EPAS1; FLI1; ZNF85; IRF9; RREB1; DMTF1; CDIP1; ST18; ZNF623; YEATS2; SALL2; PHIP; CREM; ZNF117; ZNF253; ZNF415; CEBPD; ZNF195; DACH1; MYBL1; ZSCAN18; MXI1; TAF9; ZNF667; NAB2; ZNF665; SUPT3H; MYCL; ZNF331; BANP; ZNF84; SOX2; HOXD1; CUX2; TGIF1; SPDEF; DDIT3; TRPS1; PRDM14; KLF9; CBFA2T2; PCGF3; ZMIZ1; ZNF43; HBP1; ZNF83; INSR; BARX1; BCL11A; NANOG; SOX13; NR2F6; L3MBTL1; PBX3; ZNF32; MKL2; WT1; ZNF562; INSM1; PFDN5; NFATC3; ID4; ZNF573; CBFA2T3; MDM2; AEBP1; ZNF232; PBX1; ZNF160; TRIM22; ZNF611; TCEA2; HMGB2; ZNF721; FOXG1; PAX6; BHLHE41; TDP2; PPARD; IRF7; TCF4; ASCL1; CTBP2; TSC22D3; HMGB3; NR4A2; MYRF; FOS; SNAI2; SMAD1; TFDP2; XBP1; HHEX; CITED2; ZFPM2; ETS1; JUND; NFE2; HDAC9; MTF2; PEG3; CDK2; NR0B1; HIRA; CREB3L2; TCF7L1; TCF21; TCF7; FOXO1; ATF3; CREB1
Down-regulation	117	MED24; HOXA10; FHL2; TRIM28; ZBTB18; TADA3; CARM1; ELK1; FLNA; SFMBT1; DRAP1; TRIM16; ERBB2; PAX8; MED6; SMARCD2; HDAC1; PUF60; NR2F2; CTR9; ID2; TAF10; CEBPZ; NKX3-1; SMARCA4; SUV39H1; ZNF131; CENPB; MLX; SNIP1; NFYC; HOXB7; RHOA; SLC2A4RG; EED; PMF1; CBX4; GABPB1; RBM14; KAT5; SREBF1; PA2G4; MTA1; BCL3; FOSL1; TRIM32; PHF2; TRIP6; TGFB1I1; NCOR2; KAT7; SMAD3; FOXO3; NFKBIA; REXO4; NELFB; CCNA2; TBP; BATF3; YBX1; BASP1; BRPF1; RBBP5; SMAD2; SUB1; HSF2; CNOT3; LITAF; UIMC1; CBX3; KLF2; BIRC2; FOXJ3; NR4A1; MAZ; PPP1R13L; OSR2; SAFB2; NUP62; MSX1; HOXC6; ZBTB38; SNW1; ADNP2; SOX9; ZNF410; UBP1; SMAD7; ELK3; HOXC10; BCLAF1; EZH2; NFIB; FOXD1; SP3; ORC2; SMARCE1; CBFB; PTRF; PSPC1; BRD2; KDM5D; TP53; CREB3L1; PITX1; TSC22D2; BMI1; HMGA1; TGFB1; RNF6; IKBKAP; NR1H2; WWTR1; VGLL4; RFX5; SATB2; NRIP1