Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57400	Amonafide	GSE92742	ASC	Human	24h	10uM	EID0310

Response Information :

Types	Number	Response transcription factors
Up-regulation	321	ETV1; ZNF274; PAX5; DMTF1; BACH2; KDM5A; NCOA3; GATA2; HR; SPIB; RFX7; GATA4; NFE2L2; PBX3; PAXBP1; ZNF586; AFF4; CIITA; FOS; HLX; PEG3; RELB; KLF11; FUBP1; CDK9; TBX19; SOX4; MGA; AEBP1; SP140; KLF3; NR5A2; BHLHE40; ASH1L; ZNF331; SOX2; FOXA2; NR1H2; KDM5B; MBD4; USP16; CCNE1; ZNF131; ZNF480; TCF21; HDAC9; MKL1; RNF138; SUPT5H; CTBP1; NKX6-1; ANKRD1; TGIF1; NR0B2; MDM4; BRWD1; PAX9; GLI1; TRIM24; CREG1; TFAP2B; KMT2A; ZNF516; FOXH1; WHSC1; POU2F2; MZF1; KAT6B; SP4; GTF2I; ARID1A; HMX1; PRMT2; PARP1; FOXM1; HOXD3; SAP130; ZNF532; LMO1; HHEX; KAT2A; CDIP1; TGFB1; SMAD5; ZNF134; SNAPC4; BACH1; RUNX1; MBD1; FOXE1; TSC22D1; ZKSCAN8; JUNB; RUNX2; TCF4; ZNF142; MXD3; IKZF5; EP400; MLXIP; ZNF646; AFF1; E2F1; ZNF574; PCGF3; THRAP3; LMX1B; TBX10; ZFP36L2; TRAK1; SOX10; MAF; SMARCC2; SSBP3; DDIT3; FEV; RNF4; EHF; ZNF222; WDR77; KLF15; THAP3; SMARCD1; IKZF3; PML; EHMT1; TUB; ZNF165; CSDE1; CTNNB1; ZNF552; ZNF10; ZSCAN31; PPARD; HIVEP1; PMS1; TAF1; PBX1; PIAS3; ZNF688; GFI1; ELF1; CBX2; EP300; HMGB2; THRB; MNX1; SAFB; POU6F2; ZNF419; FOXN2; ZNF8; HIPK2; ZNF211; ZBTB48; ID3; ZNF671; MITF; TTF2; ZNF175; JAK2; TAF7L; TRRAP; SMAD3; LDB1; ZIM2; ZNF510; CEBPE; MEIS2; TSHZ2; EPAS1; HMBOX1; ZXDC; FOXN1; ZNF557; GATA1; DLX6; ARL2BP; RAX; ZBTB18; SATB1; AGO2; KDM4C; SPI1; CHAF1B; MED25; TAF7; EZH1; KMT5A; CIR1; KAT2B; ZNF227; ZNF268; ZBTB17; BTAF1; PLAGL2; ZNF556; E2F6; WT1; BAZ2B; DDX54; NR2F6; SUPT6H; NOC2L; TDRD3; IL16; ZNF219; KLF13; SOX21; PIR; MDM2; TCF15; NR3C2; MLLT10; HTATIP2; TULP4; HBP1; ZSCAN32; BCL11B; NFYB; FOXJ2; GABPA; HIPK3; NKX3-2; LIN28A; SERTAD2; ZNF281; ZNF444; ZNF180; TFEB; HOXC8; CBX7; BRPF1; PRDM4; ERBB4; CIZ1; MECP2; MEIS1; TAF1A; RBL2; ETS1; WWC1; SUMO1; TCF7L2; ZSCAN18; ZNF629; ZBTB40; TP63; ZNF254; ATOH1; GRHL2; LMCD1; TBX3; DDX17; CHD1; MYCN; ETS2; ZNF117; ZBTB7A; ZNF75D; MTA1; PEX14; BLM; NFATC4; BCL11A; TAF9B; UIMC1; PATZ1; EHMT2; CALR; BASP1; MXD4; CBX6; ZNF672; TCERG1; ATF2; NCOR1; PHF1; NR1D2; ASCL1; CNOT3; ZNF43; SOX11; CITED2; CREB3L2; RERE; MYRF; BAZ2A; TAF12; NR0B1; GLI2; ISL1; E2F3; ZNF195; AATF; TP53; SALL2; RNF10; SOX17; TSC22D4; NR2F1; ZNF267; FOXF1; SMAD6; GATA6; TAL1; AR; MED1; IRF4; VEZF1; IRF6; RBBP8; CDK2; IRF9; NKX2-1; ZEB2; BBX; PCGF2; TRIM22; TCEA2; EGR1
Down-regulation	262	HMG20B; TAF11; CRK; HDAC5; NONO; CCNC; STAT6; HMGB3; PSIP1; SNW1; BIRC2; PQBP1; BRF2; DEAF1; YWHAB; ZNF44; ZNF76; PSPC1; SMARCC1; PHF20; MYC; PCBD1; TSC22D3; SAP30; ETV5; PPARG; ZNF160; UBE2B; SIX2; TOB1; PBRM1; ITGB3BP; MAFF; TRIP6; DRAP1; RELA; MEOX2; TCF25; CEBPZ; SMARCD2; ENO1; ESR1; FOSL1; BATF3; MYBL1; YAP1; CCNA2; KAT6A; YEATS2; FOXJ3; SATB2; RLF; CREB5; ZNF721; IRF7; MAZ; ZNF611; CDK7; PRRX2; MED6; IKBKAP; NCOA4; HDAC2; SMARCD3; TEAD3; NFYC; GATAD2A; RBBP5; COPS5; SMAD2; PREB; RING1; GTF3A; NR2C1; TEAD4; PBX2; ATF6; SND1; RHOA; RUVBL2; INSM1; TFDP1; SAP18; RXRB; KLF4; PSMC3IP; TRIM28; RORA; RAN; MED13; CEBPA; ZNF91; ATF3; ZNF587; KLF10; ASH2L; GTF2F1; CDK8; ZNF562; SETD3; ZNF415; HOXC6; HOXA10; ZEB1; MDFI; SIX1; ZNF14; TFAM; SALL1; HOXC10; CAMTA2; HMGB1; ZNF22; BRD2; TWIST1; CREB3L1; MEOX1; NR2E1; SMARCE1; TCF7; TOX4; CBX5; REST; ZNF468; EBF2; NFKBIA; ACTL6A; MSX1; CARHSP1; ZKSCAN1; SSRP1; LPIN2; MYCBP; ZNF410; STAT5A; SPDEF; BAZ1A; EMX2; HOXB2; MKL2; THAP4; ZNF551; IRF2; HES1; ARNTL; TBL1X; ELK3; TOX; ZNF430; HMGXB3; ARNTL2; NUP62; KDM2A; RSF1; MED27; ZNF148; RNF2; BRD7; RRN3; GABPB1; HDAC1; ZFHX4; SSBP2; KAT5; MNAT1; PRPF6; DPF2; PCGF1; ZBTB38; ZNF783; RBPMS; ING1; ZNF426; CDYL; RFC1; RBM14; USP22; CCDC59; EGR3; EN1; MTF1; ZHX3; FOXD1; FOXO4; DNMT3B; SP2; SUV39H1; HABP4; TRIM32; HOXA5; SETD2; ERG; HDAC6; HCFC2; MED17; PTRF; APEX1; DR1; ZBTB16; INSR; BCL6; KLF7; ATF5; LZTS1; ATF1; SP140L; CRY1; KDM5D; RREB1; NR4A1; ZMIZ1; ZNF32; NRIP1; ID1; RFX5; TBPL1; CDC5L; HSBP1; LEF1; CNOT2; DAXX; NFRKB; ZNF302; TBL1XR1; TLE2; NLK; FOXG1; GLI3; MYB; ATF4; ZFPM2; TSC22D2; CRYM; DEK; MED12; FOSB; ZZZ3; WWTR1; BHLHE41; ING2; TAF10; SOHLH2; VPS72; ST18; ELF5; TFAP2C; TFDP2; NFIB; CTBP2; RXRA; IFI16; CBFB; NFKB2; MAGED1; HEY1; MAFB; EED; ZIC1; KLF2; HMGA2; ID4; FHL2