Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57287	Afatinib	GSE92742	ASC	Human	24h	10uM	EID0308

Response Information :

Types	Number	Response transcription factors
Up-regulation	126	ZNF43; CERS4; NCOA1; MTF2; PHIP; IRF9; ZNF232; ZNF85; SCAND1; MYCN; ETV4; HEY2; ZNF444; NFE2; ZNF589; IFI16; TFDP2; ID1; ZKSCAN4; DEAF1; SMARCC1; ZNF253; SOX17; RFXANK; ZNF117; HDAC4; GATA4; ZNF91; LYL1; ZNF93; SP100; ZNF177; ARNTL; PEG3; MXI1; ZBTB16; HAND1; ZFHX4; RBM39; RBFOX2; BANP; ZNF195; BACH2; CREG1; ARNT2; VPS72; TRIB3; HEY1; SSBP3; ZNF136; CREM; HLX; PFDN5; FOXL2; TCEB2; DLX5; MEOX1; PIAS4; CERS6; PSMC3; CNOT6; THAP7; ZNF415; DDIT3; PRDM12; AIP; ZNF14; CCNE1; WT1; EYA1; NCOA6; MECOM; BRF2; PBX2; ETV5; PRPF6; HTATIP2; MSX1; ZNF688; TBX3; FLI1; IRF6; SOX11; TCEA2; NR1H3; GATAD2A; SMARCB1; TDP2; HBP1; SLC2A4RG; TULP4; ZNF652; ZNF426; SNAI2; TFAP2A; HHEX; INSR; TCF21; POU2AF1; EHMT2; PIR; ID3; NR0B1; RYBP; KAT6B; PCGF2; ZSCAN31; KLF11; BCL11A; HOXB5; PCGF1; MYRF; GTF2A2; FOXF2; ATF5; ZNF331; IRF7; CREB3L2; FOXG1; HOXC6; THAP11; FOXF1; DNMT1; NR2F6; HMG20B; BASP1
Down-regulation	141	PSIP1; BCLAF1; ZBTB18; XBP1; ATF1; NUP62; MYC; RNF6; PLAG1; CRK; NANOG; CCNA2; STAT5B; SIM1; ZBTB11; BCL10; CENPB; KLF6; TSC22D3; BLZF1; CCNC; CHD1; IKBKAP; UBP1; HMGA2; MYT1L; RBBP8; SMARCA4; FOSB; RNF14; TGFB1; RNF138; HNRNPD; ENO1; ZNF468; DDX5; MED4; SRF; HCFC2; VDR; SMAD3; ARID4A; NRIP1; ZMYND11; CITED2; RBPMS; ZNF574; BBX; LPIN2; PLAGL1; RRN3; CRY1; CAPN15; EGR3; TOPORS; ZNF189; HIF1A; MEF2A; SMAD7; MAGED1; TMF1; MXD4; UBE3A; JUP; RUVBL2; CENPF; CREBL2; SMARCA2; HDAC9; ING3; KLF4; PHF2; MTDH; HLTF; TERF1; ZNF146; BMI1; COPS2; TRIM22; ZNF432; RAN; RNF4; REPIN1; STAT3; RB1; ZNF226; CHD9; NRBF2; HMGB2; RNF111; NR4A1; TEAD4; TOX; ZNF217; IRF8; ZNF267; TTF2; ARNTL2; BRIP1; SSBP2; ETS2; ZNF23; SFPQ; NFE2L3; DNAJC1; FOXJ3; NPM1; TXNIP; HDAC6; CNOT3; MYB; KLF2; ERBB2; INSM1; TOB1; KLF9; SIX1; TCERG1; SIAH2; SOX9; IRF1; KLF10; USP22; ST18; ZIC1; POU4F1; AHR; TOX3; HIPK1; NR3C2; EED; NKX3-1; LITAF; NFIB; NFKB2; EGR1; LEF1; NR1D2; NCOA3; KDM5D; NFKBIB