Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57205	Varenicline	GSE92742	SKB	Human	24h	10uM	EID0305

Response Information :

Types	Number	Response transcription factors
Up-regulation	183	MTF2; ETS1; ZNF611; EGR2; ZNF250; ZNF682; SKIL; ZNF43; ZNF124; NR4A3; SIX3; SATB1; ZNF93; NFE2L2; ZNF345; ZNF257; SPIB; SOX18; ZNF623; ZNF85; ZNF160; PRDM14; ZNF44; SUPT3H; ZMIZ1; ID4; ZNF117; MED20; RYBP; ZNF235; TTF2; NOC2L; ZNF669; NR4A2; TRPS1; ZNF107; TLE2; ATF2; TERF1; ZNF721; NFKB2; ZSCAN18; ZNF695; TAF11; ZNF426; ZNF331; PIAS4; DLX4; ZNF177; ZNF415; ZNF232; CREB1; SPDEF; TFAP2A; ZNF253; ID3; ZNF141; BARX1; NR5A2; ZNF665; RAD21; ASCL1; EZH2; BRCA1; MEIS2; PHIP; E2F3; CAMTA1; SALL2; ELF3; ZNF239; SKI; ZIC3; PNRC1; NEUROD1; PBX1; MED14; ZNF675; LHX3; L3MBTL1; ZNF33B; EHF; ZNF573; MYBL1; PEX14; TGIF2; NCOA3; ZNF131; TULP3; RXRA; FOXF1; PRDM1; MEOX1; ETV6; ZSCAN16; ZSCAN9; ZNF83; TCF3; ZNF217; ZEB1; ZNF562; HDAC9; MYCL; HLX; MED7; DMTF1; NR2F6; SSX1; NR4A1; UBE2L3; INSM1; MEOX2; E2F8; ZHX2; ZFP69B; ZNF667; TCF7L1; TRIM29; ZNF302; IRF4; SUPT5H; ZNF273; CREM; JUP; TWIST1; HES1; PCGF3; PSMC3; CTBP2; ZSCAN31; ZNF165; RSF1; EGR1; ZFPM2; REL; ST18; ZNF91; KLF9; TAL1; TCF7L2; ZNF195; ZNF350; HOXD1; DACH1; FUBP1; VPS72; CBFA2T3; CALR; ERBB4; POU2AF1; SP140L; KLF7; ZNF430; CERS6; ACTL6A; ELF5; LITAF; ID1; ZKSCAN1; BCL11A; ATF5; ZBTB20; ETV1; EGR3; FOXO1; MYB; FOXF2; HOXB2; DDIT3; ZNF544; ZNF423; NFE2; MED13; BTG1; SOX11; NFATC3; PBX3; ATF3; ZIC1; MYBL2; LEF1; PEG3; CRK
Down-regulation	197	TCERG1; TRIM28; DAXX; VGLL4; SIAH2; GTF3A; SREBF1; SREBF2; NFYC; TSC22D3; SETD2; HOXA10; PBRM1; ZNF473; ZBTB11; SNIP1; FOXJ3; SCAND1; PIR; BMI1; USP22; DEAF1; COPS2; USF2; CREG1; TP53; DDX54; HDAC2; MAF; KAT5; TSC22D1; NRBF2; SPEN; ZNF580; TBP; FOSL2; ZBTB1; RFX5; ZNF263; HSF2; FLNA; HDAC4; CTNNB1; CCDC59; SMAD2; PHF1; TADA3; RNF6; FHL2; FOXO3; LDB1; NR2F2; IKZF5; NRIP1; KAT7; SOX4; HDAC6; ELK1; SNW1; ID2; PSMD9; YBX1; ABT1; ELF1; SP100; HDAC1; DBP; MZF1; NCOA6; ZNF512B; HMG20B; MAX; CARM1; ZNF227; KDM2A; YAF2; DRAP1; YBX3; ZNF384; TRIM16; ATF4; UIMC1; JARID2; HOXC6; ZNF281; MEF2C; ZNF134; USP21; RBBP7; BRD2; NCOA4; ETV5; NR2F1; KLF2; BCL10; TGFB1I1; URI1; ERBB2; TRIM32; HCFC1; IKBKAP; SETD3; YWHAB; HDGF; CTR9; CIC; ZMYM2; RHOA; ZNF274; ARNT; CSDE1; ADNP2; TGS1; NEDD8; TCF12; ZBTB18; SLC2A4RG; HIPK3; AATF; FOXL2; EDF1; ZNF536; SMARCA4; MED6; RXRB; TAF10; MITF; PRMT2; BASP1; RNF10; MBD2; MAFG; CENPB; ECD; PLAGL1; NKX3-1; SAP30; TFAM; PTTG1; LMCD1; MED24; C1D; AIP; TCEA2; UBP1; SMARCA2; TBX3; RUVBL2; CITED1; POU4F1; KDM5D; HOXB7; CDK2; NELFB; SUB1; PCGF2; MED21; TDRD3; ZEB2; KDM5B; GABPB1; MED23; NUP62; HOXC10; TFAP2C; RBM39; UBTF; TRIP6; NPM1; MYCBP; HMGA2; CBX7; PDLIM1; SAP18; FOXD1; HOXB6; MAGED1; BRPF1; SMARCD3; GATA3; CREB3L1; SMARCD2; TXNIP; HEY1; OSR2; MED1; SNAI2; BRD4; FOSL1; EMX2; SMAD1; STAT5B; WWTR1; SOX9; GATA6; ZBTB38; WT1