Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57192	Givinostat	GSE92742	SKB	Human	24h	10uM	EID0305

Response Information :

Types	Number	Response transcription factors
Up-regulation	94	BRCA1; ZNF721; ZNF611; TRIM16; NFX1; ZNF44; ZNF160; PIAS1; TLE2; EPAS1; SFPQ; TFCP2L1; CDYL; KLF6; FOXA2; FOXF1; KLF10; NFYA; ZNF143; ARNTL; ING2; INSM1; SETD2; TCF7; KLF4; ITGB3BP; IRF1; EZH1; TRIP4; NFATC1; KLF13; PITX1; SREBF1; ZKSCAN1; CREBL2; UBP1; ZFPM2; IRF6; MEOX2; TBPL1; TFAP2C; NCOA3; CREM; SMAD2; PSMC3; SSX1; RAN; HOXB5; NR3C2; TCF12; PTRF; CBFA2T3; TBX3; PDLIM1; ATF3; TADA3; BRPF1; AHR; BBX; CREB3; EMX2; PSIP1; BRD2; CBX7; TXNIP; MYCN; PAX6; ZEB1; ZNF423; LITAF; KLF9; TLE4; SOX9; MED24; OSR2; CRY1; LPIN2; SNAI2; BATF3; VEZF1; MITF; PCBD1; CRK; FHL2; ZBTB38; MAFF; ZBTB20; BASP1; ESR1; HOXB2; HMGB2; NKX3-1; BHLHE41; RBPMS
Down-regulation	122	FOSL2; GTF3A; TCF15; ZNF667; SOHLH2; ZNF574; WDHD1; ZNF205; HDAC7; BRCA2; BRIP1; ZNF646; MED14; SPIB; SUZ12; PBX2; NKRF; THRAP3; CBX5; BATF; ZNF580; VDR; BTAF1; MYC; MLXIPL; PAXBP1; SOX4; IRX4; E2F3; PA2G4; SNAI1; ID4; NFAT5; CENPF; ABL1; MXD3; PLAG1; USP16; ARID1A; MDFI; CDC5L; INSR; TFAP4; HMGN3; CEBPE; HOXA5; SAP30; PHIP; ZNF107; AFF1; CHD9; CHD1; KDM5C; ZNF83; MGA; ZNF135; ELF5; MAZ; TCF3; HOXB3; MED15; ZBTB1; ZNF93; SAFB; ZNF124; CARM1; ZNF671; TCF7L2; ZNF410; ZNF331; CCNC; ZNF552; E2F8; FOXC1; SUPT5H; TAF9B; TAF10; TGIF1; IRX5; DMTF1; YAP1; THAP11; TP63; SMAD1; MED12; POU4F1; CEBPD; ELK3; NR2F6; ERBB2; FOS; CITED2; NFATC4; TAF1D; NFIC; EGR1; SOX2; MAGED1; RBM39; ZNF195; TSC22D1; NFE2; TCEA2; ELF4; TERF2; ZBTB18; LIN28A; NFATC3; ERBB4; PPARD; SSBP2; HMGA2; POU2AF1; HIC2; HOXB7; MEF2C; NR4A2; JUP; ID1; HOXC6; ZNF91; ST18