Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57183	Thiostrepton	GSE92742	SKB	Human	24h	10uM	EID0304

Response Information :

Types	Number	Response transcription factors
Up-regulation	418	NFE2L2; SIX2; GTF2A2; SMARCC1; DNMT1; ARID1A; GMNN; ATF3; SSRP1; RELA; ARNT2; BRD7; TFAP2A; DRAP1; ILF2; PFDN5; TADA3; MECOM; FOXK2; BRF2; PCGF2; JUN; RFXANK; DEK; GTF2F1; XRCC6; SUPT4H1; PSMC3; FOXO3; ASXL1; CDC5L; CTR9; MXI1; PMF1; TCF25; ENY2; SMARCA5; CREB3; ZNF692; KAT5; TCERG1; RUNX3; RNF10; RHOA; MLX; WIZ; RBFOX2; SAFB; RUVBL1; HDAC5; SSBP3; HIPK2; DPF2; PCGF1; GTF2A1; HMGB1; MTF1; SMARCB1; HOXB2; PBX2; BACH2; AR; PA2G4; HDGF; CBFB; THRAP3; RBPJ; TCEB2; RBM39; MED16; SMARCD3; HOXB6; TP53; TBPL1; MNT; SREBF2; YBX1; MEIS1; ARHGAP35; DEAF1; CHD8; DNAJC2; GLI3; TULP3; AATF; SNAI2; HDAC1; GATAD2A; PRPF6; HOXB3; LDB1; SUPT6H; MYRF; MDFI; FOXD1; ABT1; RYBP; ZNF266; MSX1; MAFG; HMGXB4; GABPB1; TFDP1; ZNF593; SUZ12; CCNE1; KAT2A; FOXM1; KDM2A; PARP1; NFIX; KLF11; MED24; BAZ1B; NOC2L; TSC22D3; PSMD9; YEATS2; RERE; RAN; HOXA11; CNOT2; FOSL1; SMARCE1; ZNF335; RXRB; PCBD1; E2F6; UBE2L3; PPRC1; AIP; ZNF415; FHL2; USP21; PEX14; CBX6; HOXD11; MITF; TCEA2; BTF3; COPS2; TOX4; TCF20; CTNNB1; MAFF; ATF6; ZNF394; CCNH; SREBF1; ZNF232; ZNF646; COPS5; MYCBP; MEN1; NSD1; VPS72; SP3; ERCC3; PIAS3; RING1; ETV5; ZNF136; HIF1A; AES; VGLL4; TWIST1; MTDH; ZNF195; APEX1; TSG101; ZBTB17; PRKDC; ZFHX4; HLX; PEG3; GTF2IRD1; CARM1; SETD2; HOXB5; MMS19; CSDE1; HOXD10; ZNF274; HOXD9; NACA; HAND1; HLTF; ZNF544; PLAGL2; ETS1; NFKBIA; ZNF331; SIN3B; NKX3-2; NFKB2; JUND; GMEB2; ZNF408; LOXL2; MYC; HEY1; NR0B2; ZNF783; MED15; TRAF6; LZTR1; TULP4; ZFP36L1; TAF7; SHOX2; WT1; SETD3; RBBP8; ZNF768; CITED1; TAF6; PHF1; ENO1; TRIM28; ARNT; CBFA2T2; YBX3; KDM5D; SCMH1; MAZ; RB1; MED13; POLR3C; HIF3A; TAF10; ITGB3BP; TCF4; TSC22D1; TBP; SUMO1; CEBPG; E2F3; TSHZ2; ZNF611; NAB2; SIRT2; ZNF410; EYA2; KAT6A; TEAD3; ZHX3; DDX17; ZNF35; ZNF205; PHOX2B; TCF12; TSC22D2; NKRF; ZNF133; KDM5B; HAND2; SNIP1; ZNF83; TRRAP; SUB1; TRIM16; DDIT3; EHF; NCOA6; ATF5; PBX1; ZNF43; DLX5; EYA1; EHMT2; TBL1X; CBX5; CALR; SNW1; ELK4; RBBP4; KAT8; ELK1; HCFC1; PCGF3; NCOA3; CDIP1; HTATIP2; SMARCA1; TP73; CEBPB; CIZ1; SP100; IFI16; THRB; NFKB1; TLE2; SOX9; ID1; CREM; SUPT5H; TRIB3; STAT5B; HDAC2; NFIC; CHD4; ECD; SETDB1; CTBP1; NCOR1; SAP130; CD3D; BTAF1; RLF; SAFB2; RAD21; TAF1D; BCL6; PTTG1; BRD4; NFYC; SOX12; CERS4; SND1; FUBP1; YAP1; RBL2; CDK2; RUVBL2; INSR; ZNF562; BANP; CXXC1; ATF4; PHF8; HBP1; ZNF324; TERF2; PIAS4; CNOT6; SIRT7; NONO; STAT4; LITAF; ZBED1; USP16; TRIP6; MED21; RARG; ZNF337; CALCOCO1; ATN1; ZNF302; HMG20B; ZNF580; HDAC3; FOXO4; PNRC1; SMARCD2; SOX5; UBE2I; CCDC59; HIVEP3; THAP4; TCEA1; ID2; MDM2; CREB3L2; TRIM27; ZIC3; TGFB1; TFAP2C; MBD2; KLF7; C1QBP; NR4A3; PITX1; PUF60; ZNF148; PIR; SALL2; BRD2; MED6; TCF7L1; CRK; NPM1; NCOA4; ST18; TAF9; MEOX1; ZNF12; MED1; USP22; SOX4; BAZ2A; MAF; NR1H3; NFE2L1; URI1; ZNF264; ZNF91; SCAND1; BAZ1A; ZNF160; RNF138; ISL1; NKX3-1; EDF1; PBX3; CNOT3; BTG1; ZNF146; CERS6; CREG1; ZEB1; SOX11; YWHAB; HIRA; EMX2; HOXB7; HOXA10; CITED2; MAFB
Down-regulation	431	GATA6; KLF2; ZNF180; MYB; ZNF112; ZNF227; FHL5; CSDC2; BRIP1; MNAT1; FOXE1; WWTR1; BRWD1; PAWR; BAZ2B; MYT1L; SPIB; EGR2; NR3C2; NRBF2; WDHD1; BRCA2; TFEB; NKX2-1; IKZF1; ZNF493; ZNF33B; DBP; ZNF510; NANOG; ZNF589; ZNF556; ELF5; HLF; PITX2; EN2; ZNF764; NR1D2; ZSCAN16; OVOL1; SUV39H1; TRIM32; ZNF124; NPAT; ZNF236; ING3; ING1; SMAD6; CBFA2T3; NFX1; BCL11B; NR5A2; SOX18; ZNF7; ZBTB6; UBE3A; NR3C1; FOXN3; ZSCAN2; ERBB4; ZNF257; MLLT10; TRIM22; ZNF234; ZMIZ2; SOX3; MYF6; IRX5; RBL1; ZNF770; FOXJ3; E2F2; ZNF34; ERG; IKBKAP; EGR3; LHX6; THAP10; ZNF443; MED14; LHX3; ZNF22; SOX21; ZNF292; ZMYND11; ZNF223; HOXA1; CDK7; TGFB1I1; RFX7; HR; THAP9; ZNF551; BPTF; JUNB; HES2; SMAD3; ARRB1; WWP1; ZEB2; ZNF226; ARNTL2; POU4F1; BLZF1; ZNF45; ZNF506; MED7; PPARG; NR2F6; ZNF225; HNF4A; HMG20A; E2F8; PPARGC1A; HOXB9; ZNF184; EP300; ATOH1; BLM; ZNF682; ELF2; ERF; FOXC1; ZNF623; MAP3K10; PSPC1; FOXH1; ONECUT2; ZBTB25; TFAP2B; SSX3; ZNF442; SNAPC4; LMCD1; RXRG; LIMD1; SRY; TAF1A; LYL1; HESX1; POU3F3; KMT2D; TMF1; ZFX; SCAI; ZNF696; IRF5; ZBTB44; MAPK8IP1; MEF2A; ZNF189; PMS1; ZNF695; LHX1; ZBTB3; IRF4; YBX2; RFX2; NR1I2; SMAD7; ZNF304; NFYB; KDM5C; ZNF254; IRF2; BCLAF1; ZNF267; MTF2; ORC2; E2F5; SIX6; DNMT3B; ARNTL; ZNF586; ZFP2; CHAF1B; ZNF217; IL16; TXNIP; BACH1; MAK; NR4A1; ETS2; ZNF813; ZNF222; KLF13; BHLHE41; BRD3; TCFL5; REPIN1; ZNF41; TEAD4; FOXD2; ZSCAN31; SUV39H2; ZNF711; SMAD9; GATA2; PRDM5; ZNF391; ZNF16; SHOX; ZNF157; BATF; ARID4A; NFIB; ZZZ3; FOXJ1; PLAG1; CIITA; NR5A1; ZNF423; HOXA7; ZNF85; ZNF614; ZNF343; POU3F4; KLF10; ZNF571; POU3F1; JUP; SKI; HDAC11; RBPMS; GABPA; PPP1R13L; IKZF4; FOXD3; ING2; SPI1; MYCL; WNT4; DNAJC1; GFI1; NKX2-8; MEOX2; GSC2; TAF1; ZBTB20; MZF1; AFF1; ZNF200; PRDM10; MDM4; EMX1; THAP11; PRDM14; EGR1; PRDM1; CENPB; NFATC1; ZSCAN12; POU2F1; CBX7; AEBP1; VHL; KLF4; TAF9B; EGR4; SMAD5; SUPT3H; ZBTB14; HNF4G; ZNF10; CARF; BBX; YAF2; UTF1; PATZ1; ZNF529; ZNF446; PIAS1; HEY2; NR6A1; NRL; TAF4B; ZNF175; HOXA3; BNC1; ID4; TBL1XR1; PEX2; ASCL2; TAF7L; PML; ID3; RFX1; ZKSCAN3; PRRX1; PSMC3IP; RCOR3; MEF2C; PRDM13; RNF14; JAK2; DDX54; ZNF211; SOX15; ZNF174; HMGB2; CCNA2; NCOR2; ZNF235; IKZF5; SAP30; CHD1; BASP1; POU2F3; FOSB; FOXJ2; PTRF; SMAD2; KAT6B; ANKRD1; KLF5; MYOD1; NLK; ATF1; ZNF419; TDRD3; NFE2L3; IRF1; NKX2-2; PROX1; CREB1; SRF; PAX5; SATB1; LEF1; TP63; MTA1; SKIL; ZNF250; TOX; DYRK1B; THAP1; ZNF8; CAPN15; ADRB2; ZNF140; OLIG2; ZNF557; ELF4; USF2; CDX2; ZNF253; TOPORS; KLF9; ZFPM2; BCOR; STAT1; BRCA1; CDX1; KDM5A; SPEN; REST; LHX2; TCF7; ZHX2; ASCL1; DACH1; FOXA2; NEUROD1; NR2C1; HIC1; SOX13; SNAI1; TFCP2; NFATC3; TBX2; KDM4C; ZNF671; SOX10; TLE4; ZBED2; ELK3; ZNF552; CAMTA2; ZNF134; SMAD4; ZNF239; GLI2; RELB; CREBZF; SATB2; GCFC2; ZNF202; SSX1; TRIM33; HHEX; NR2F2; ZNF573; STAT6; NKX2-5; CUX1; YEATS4; HES1; ZNF107; ZFP36L2; ZNF23; ZNF84; NR1H2; CARHSP1; EPAS1; RBBP7; TGIF1; HOXC6; CRYM; ZNF165; REL; NRIP1; SMARCA2; HDAC4; TERF1; FOS; NR2F1; PBXIP1; ELF1; SFPQ; DLX2; PAX6; SSBP2; MYBL1; AGO2; TBX3; ETV1; ERBB2; PSIP1; ZNF430; HOXA5; POU2AF1