Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57182	Alitretinoin	GSE92742	SKB	Human	24h	10uM	EID0304

Response Information :

Types	Number	Response transcription factors
Up-regulation	411	MECOM; TFAP2A; ARID1A; RELA; BAZ1B; ETS2; GTF2A2; CREB3; TSC22D3; TCF20; CBX5; MTF1; PBX2; PHF8; ADNP; DPF2; ATF6; NAB2; GLI3; CTR9; MITF; SMARCC1; PFDN5; KDM5D; SMARCA1; DRAP1; TP53; SMARCA5; PRKDC; RERE; ARNT2; NFIL3; RSF1; PA2G4; DLX5; TCF25; MEIS1; ZNF248; FOXO3; FOXA1; CCNH; TFDP1; SSBP3; MYC; YEATS2; ZFY; LDB1; KAT5; TOB1; JUN; ATF3; TOPORS; SOX2; PCBD1; HMGB1; PIAS3; GMNN; FOXF1; HDAC7; TSG101; CCNE1; CHD4; JUND; ZSCAN18; SMARCA4; WHSC1L1; MKL2; UBE2L3; TCERG1; BACH2; TRIM22; CLOCK; GON4L; MYCBP; WDR77; RBBP8; VPS72; IRF2; ILF2; MED20; TRPS1; FOSB; TRRAP; TULP4; OVOL2; MED15; NUP62; SIN3B; ZFP36L1; ZNF33B; ESR1; WT1; SUZ12; SREBF2; SAP130; ZNF205; PURA; MED13; XRCC6; PPARD; CARM1; POLR3C; PMF1; BRD7; CHD8; TGFB1; ELF3; CBX6; SMARCC2; POU2F2; TAF11; KMT2A; STAT4; VGLL4; EHF; MDM2; ZNF3; PIR; EP400; ZNF195; FOXO1; MDFI; NFYC; CHD3; KDM2A; SP100; MBD2; TCEB2; HIF1A; DNAJC2; PKNOX2; KLF10; VEZF1; CDK7; NPAT; NKX3-2; NSD1; E2F3; NFIX; TBL1X; NCOR1; CREM; HMGB3; CRYM; ZNF768; FOXM1; UBP1; PARP1; TSC22D1; SSRP1; TAF4; TFAM; BRF2; PDLIM1; HDAC6; UIMC1; ZFPM2; CTBP1; SF1; ZNF692; BRD4; ZNF165; PLAGL2; ZNF281; NFKBIA; TCF12; RB1; RNF111; ZFHX3; ZNF334; TRIM33; FOXK2; SHOX2; ZNF217; ERCC3; RBPJ; ZNF587; MECP2; GATAD2A; SMARCD3; SKIL; RBFOX2; ELK1; TCF21; NR1H3; RBM14; TBPL1; CSDE1; LPIN2; CREB1; SMARCD2; ETS1; GATA3; SOX5; FOXL2; NCOA3; NFATC4; STAT3; TAF6; LZTR1; ZNF141; DEK; ZHX3; ZNF589; EGR4; HOXB3; HCFC1; SUMO1; STAT6; RBPJL; ZNF148; HMG20B; MAGED1; HOXA11; ZNF646; SMAD3; TSC22D2; C1D; ZBTB44; ZSCAN9; NFAT5; SNIP1; HDAC1; DLX4; RNF141; THAP7; NFKB1; CD3D; SND1; DDX17; HNF1B; ZNF816; ASH2L; ZBTB1; XBP1; HOXB6; TADA2A; UBE2I; ZNF274; SMAD1; GRHL2; SMAD2; ZFHX4; ID1; SUPT7L; KLF11; ZNF331; TOX; TCFL5; ACTL6B; CRK; BCL11A; PITX1; ELK4; MED12; HMG20A; MED7; SIX2; ECD; SUPT5H; ACTL6A; NLK; ZNF580; ZNF324; DLX6; BCL10; PCGF3; STAT2; GABPB1; CREBL2; MAFF; ZNF135; MEN1; SMARCB1; SMARCA2; FOSL1; PBRM1; MLXIP; EYA3; KAT6A; NR2C2; ZNF215; ASCL1; MYB; WHSC1; TERF2; EZH1; HSBP1; KLF6; ZNF415; MYBL1; SOX4; SNAI2; GLI2; YBX1; MED21; IFNB1; THRAP3; YWHAB; RYBP; HDGF; ARL2BP; ZNF528; DNMT1; EHMT2; NCOR2; SATB1; ZNF629; SETDB1; TFAP4; ZKSCAN4; NR2F1; TBX1; KDM5B; GTF2IRD1; SAP30; BAZ1A; TTF2; SREBF1; HDAC9; SCMH1; CNOT6; FEZF2; ZNF654; ZNF835; NR4A1; BPTF; DYRK1B; PPARG; HLTF; FOXF2; ETV5; TULP3; BHLHE40; KAT2B; CDK8; EED; CUX1; LZTS1; SMAD4; MNT; POLR2A; BAZ2A; AR; RELB; MMS19; ZNF576; PLAGL1; PEG3; CDK2; SMAD5; L3MBTL1; ZNF212; NFATC3; RBL2; CIZ1; ATF1; HTATIP2; BARX1; SPDEF; NEUROD1; E2F2; IFI16; OLIG2; SP3; KLF12; TBP; MEF2D; PSMC3; SOX12; CARF; TFDP2; NFIC; EDF1; ZKSCAN1; UBE2B; COPS5; TLE4; FOS; RUNX3; SOX13; ZMYND11; PBX1; LEF1; TAF5; MED1; ZNF354A; SP110; BASP1; PIAS2; HOXB2; EGR3; TAF7; RBBP4; HOXC10; HMGA1; KDM5A; AFF1; TWIST1; HIPK1; ETV1; NFE2; ZNF544; SOX17; TBL1XR1; TFAP2C; MAF; TBX2; KLF4; CEBPB; TRIP6
Down-regulation	437	ATF4; PUF60; BATF3; MNAT1; SIX1; ZNF506; RXRG; FOXJ3; MEOX2; TEAD4; ZNF227; ZNF263; GATA6; ZNF219; CSDC2; ZNF189; UBE3A; IKBKAP; PTRF; ZNF10; KLF2; ZNF177; LHX3; LMCD1; ERG; ZNF423; BRCA2; FOXC1; BCL11B; FHL5; IRF7; SIM1; CHD1; HOXD13; PSPC1; ZNF174; HESX1; ZFX; IKZF1; ZNF468; PITX2; ZNF536; ZNF551; C1QBP; MNDA; KDM4C; ING1; SAP18; JAK2; HOXA1; ZNF408; MYF6; WWTR1; ZSCAN2; MED27; EN2; ZNF652; HOXC6; CCNC; DBP; HMGB2; PCGF1; HSF4; BRPF1; IKZF5; BAZ2B; EBF2; ZNF614; TCEA1; ZFP36L2; ZNF34; TCF7; BACH1; SOX9; KAT6B; TBX10; ERBB4; HOXA3; HOXD9; HOXA7; ZNF510; ZNF529; TAF9; DAXX; PAX6; CASZ1; CRY1; ZNF146; SALL1; HNRNPD; ESRRG; LHX6; SCAND1; LHX1; NKX2-2; TBX19; GTF3A; TRIB3; ZZZ3; JARID2; ZNF107; ARNTL; NRF1; ELF1; TCF7L2; ZNF180; SPI1; ZNF467; ZNF721; ZNF446; IRX5; RING1; ZNF226; CEBPA; ZNF8; SOX15; MAPK8IP1; TFEB; AIRE; ERF; HOXD10; NR3C1; EWSR1; ZEB2; SSX7; PRRX2; LOXL2; POU4F1; ABL1; ZNF586; APEX1; HOXD11; ZNF512B; ZSCAN5A; MTA1; SMAD6; HNF4A; PITX3; NR5A2; HOXC5; SUV39H1; ZNF292; STAT1; MAK; CXXC1; ZNF343; ZEB1; ONECUT2; SOX18; SCAI; BCLAF1; ZNF32; HOXC11; MYOD1; TGS1; EMX1; PNRC1; RREB1; JUNB; NEUROD6; ZNF84; GFI1B; BHLHE41; TAF9B; CBX4; ZNF571; PRDM12; MYF5; ZFP2; CBX3; ZNF91; PROX1; TLX1; IRX4; HLF; KAT8; MYRF; IRF3; IRF6; ATF7IP; SIX6; ZNF184; ZMIZ1; LBX1; MYT1L; NANOG; HDAC11; NFIB; GCFC2; DLX2; KDM5C; UTF1; NEUROG3; LIMD1; NPAS1; NEUROD2; AEBP1; REPIN1; TBX3; THAP3; APBB1; ZNF254; CCDC59; HIRA; ZBTB25; MLLT10; ZNF134; MAP3K10; PIAS1; CDIP1; ZNF264; DNAJC1; ARID4B; NKX2-5; ZNF236; WWP1; ID3; USP16; SOX21; CENPF; DDIT3; YBX3; NR2E1; POU3F2; ZNF473; BIRC2; BATF; ZNF335; IKZF4; POU4F2; ING3; PRDM14; ENY2; ZNF426; CNBP; HOXD3; KDM4A; BBX; MTF2; FOXN3; ZBTB11; ATF2; ZNF140; ZNF211; RUNX1; PRDM1; TLX3; MXD3; PREB; ZBTB3; HOXA4; PBXIP1; BRD8; ZXDC; MYCL; TFAP2B; ZNF688; NR3C2; ZNF253; SSBP2; ZNF112; POU2F3; PAXBP1; ZNF764; NR5A1; MEF2C; NRIP1; ATOH1; MYCN; THAP11; TXNIP; MBD3; PRDM2; WDHD1; BTF3; RNF6; ZKSCAN3; SPEN; RORA; LYL1; KMT5A; HOXB8; ZNF493; ZMYM2; ZNF304; NR1H2; ZNF7; PMS1; FOXE1; IRF5; ELK3; ZNF350; ZNF710; ZNF124; SIM2; RFX1; PML; MED17; BMI1; PRDM13; AHR; EP300; THAP9; CREB5; ZNF160; CERS6; BRD3; PTTG1; ZNF696; NHLH2; HIC2; ZNF668; POU2AF1; PRRX1; OSR2; NKX2-8; SFPQ; HES1; NR2F6; GABPA; ZNF93; CAMTA1; ZNF222; CARHSP1; MYOG; ARID5B; ZNF44; PSIP1; IRF1; MEF2A; PRDM10; ELF2; THAP10; HOXC4; ZSCAN12; MZF1; RLF; DNMT3B; CEBPG; GATA2; CCNT1; NR1D2; POU5F1B; BRIP1; ERBB2; ARID3B; CAPN15; MDM4; ZNF430; ETV4; BCL3; ZNF24; CENPB; ZNF770; AFF2; CEBPD; YAP1; PHIP; ZNF419; YY1; TGFB1I1; ZNF623; ZNF593; TLE2; ZNF573; PEX2; HOXA5; NCOA4; KLF13; CIC; ZSCAN32; ZNF345; ID2; INSM1; HABP4; HMGXB3; SSX1; RUVBL2; ATF5; CEBPZ; NELFB; USF2; GFI1; SOX11; BTG1; CNOT3; DACH1; SOX10; MED24; CDYL; CITED2; SIX3; KAT7; NR2C1; ENO1; YEATS4; MEIS2; ZNF611; TOX3; HEY1; CHD7; PHF1; ZNF557; BLM; BRCA1; CREG1; MED6; RFX5; LITAF; MAFB; ZBED2; NPM1; EGR1; ZNF302; RCOR1; RBPMS; SMAD7; SATB2; ZBTB38; RNF138; TRIM29; GTF2I; ST18; ID4; ZNF131; ZNF83; PQBP1; FOXG1; HEY2; NFE2L1; FLNA; IRF4; HDAC2; TP63; HOXB7; EMX2; NR2F2