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Overview Perturbagen Expression Profiles Transcriptional Responses
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Overview Perturbagen Expression Profiles Transcriptional Responses
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Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID57181 Varenicline GSE92742 SKB Human 24h 10uM EID0304
Types Number Response transcription factors
Up-regulation 395 NFE2L2; GTF2A2; SIX2; TFAP2A; DNMT1; TFDP1; ARID1A; TSC22D3; DRAP1; PMF1; RHOA; RFXANK; YEATS2; ENY2; ILF2; BRD7; ARNT2; ATF6; SSRP1; RUVBL1; CBFB; SMARCA5; FOXO3; RBFOX2; FOXD1; JUN; PARP1; GTF2A1; TRIM16; HDGF; HMGB1; TADA3; SMARCC1; HOXA11; GMNN; SREBF2; PFDN5; FHL2; TCEB2; XRCC6; HMGXB4; SMARCB1; BACH2; TCERG1; SP3; TCF25; SREBF1; HOXB6; ZBTB17; SHOX2; RBM39; WIZ; AIP; MED24; NOC2L; FOXK2; CBX5; CCNH; PCGF3; PRKDC; SUB1; PSMC3; RNF141; ECD; SMARCE1; RNF10; MYRF; UBE2L3; MYC; TBL1X; PCBD1; SAFB; TBPL1; ZHX3; MYCBP; ZFY; ZNF133; HIPK2; CNOT2; NKX3-2; PA2G4; CDC5L; HDAC1; PDLIM1; GLI3; MNT; NSD1; DEK; CDK7; HIF1A; USP21; PKNOX2; TP53; DPF2; MDFI; ZFP36L1; MTDH; TWIST1; COPS5; ZFHX4; MED16; HOXB3; MECOM; PSMD9; PRPF6; PIAS3; PITX1; RBPJ; FOXM1; TRAK1; CTBP1; KDM5D; APEX1; TCEA2; ZNF816; MED23; RUNX3; CTR9; TSG101; ERCC3; TULP4; ZNF593; MTF1; LOXL2; CHD8; DDX17; CCNE1; SP140; ZNF528; ETV5; MLX; TCF4; CARM1; SMARCD3; YBX1; TCF20; NEDD8; RAN; DNAJC2; NR0B1; TBX1; SOX9; MED21; SOX12; ASXL1; AR; VPS72; MAGED1; TAF1D; CNOT6; NFIX; VGLL4; EN1; JUND; GON4L; ZNF692; UIMC1; ZNF334; RERE; WHSC1; SNAI2; SMARCA1; PBX1; ZNF232; NCOR1; POU3F2; HMGB3; LZTR1; RUVBL2; SETD3; SP100; AES; HDAC2; XBP1; MSX1; PCGF2; GABPB1; HIF3A; NCOA6; ZBTB18; HOXB2; UBE2I; MED20; YBX3; HDAC5; CDIP1; MBD2; RELA; CALR; HLX; HEY1; TAF6; TBX6; NCOA2; THRAP3; BRF2; TCF7L1; NFKBIA; BTF3; SIN3B; MITF; PEX14; RNF4; E2F6; SUZ12; RFC1; KAT5; SUPT4H1; POLR3C; RBBP4; HCFC1; ARHGAP35; SETD2; TULP3; MEN1; ABT1; DEAF1; CTNNB1; CITED1; NR2F6; MEIS1; SAP30; GATAD2A; KAT2A; KLF11; CREB3; HOXB7; MMS19; RBBP8; HOXC6; HOXD10; TCEA1; NAB1; GMEB2; NCOA3; MXD3; ATF4; HMG20B; ENO1; PIR; CBX6; ZNF532; BRD8; ZNF83; HMGN3; RB1; MBD4; TCF12; BTAF1; CTCF; ZNF205; MED15; MDM2; POLR2A; IFI16; TP73; ATN1; CEBPB; HAND1; SOX2; PLAGL1; GTF2IRD1; PHF20; PAX9; HOXB5; ZNF335; ZMYND8; TGIF1; HHEX; ARL2BP; GTF2F1; PHOX2B; HIVEP3; HMGA2; CDK8; AATF; TAF9; ZNF268; PCGF1; CERS6; SNW1; ZNF580; MED13; FOXO1; TSC22D1; CBX3; SP140L; PPARD; WDR77; NONO; ZNF611; SUMO1; HLTF; KAT8; FLI1; TSHZ2; CERS4; NCOA4; ITGB3BP; SUPT6H; EHF; EDF1; TBP; DLX5; C1QBP; HDAC9; PIAS4; ID1; ZNF415; THAP4; PLAGL2; FUBP1; ZNF512B; CSDE1; FOSL1; CREM; KAT6A; SETDB1; DDIT3; ZNF302; EYA1; TRIB3; GTF3A; COPS2; TERF2; ZFPM2; ABL1; ZNF195; ZNF274; E4F1; THAP11; HOXA10; VDR; SIX3; USP16; MYBBP1A; ZBED1; E2F2; MAF; USP22; CIZ1; HOXC10; TRIM29; KLF7; EYA2; TLE4; SMAD1; MAX; INSR; RYBP; RBBP7; KAT2B; PTTG1; CEBPG; NCOR2; URI1; BHLHE40; ID2; TRIM28; TRIM22; ADNP; ZNF544; SIAH2; HTATIP2; TAF7; ZBED4; SLC2A4RG; SP110; ETV4; PAXBP1; CREG1; SSBP2; EMX2; HSBP1; KDM5B; ST18; ZNF281; YWHAB; PUF60; ALX1; CHD4; NFE2L1; HDAC6; MYCN; SOX17; HBP1; MXI1; TRIP6; ZMYM2; SCAND1; ATF5; SOX11; BCL6; MEIS2; ZBTB16
Down-regulation 455 GATA6; ZNF180; ZNF124; CSDC2; HLF; ZNF764; ZNF443; SPIB; IRX5; ZNF510; ING3; GATA3; MNAT1; ZNF112; ZNF556; DBP; ZSCAN16; IKZF1; EGR2; NANOG; ING1; ZBTB44; BCL11B; ZNF551; LHX6; TRIM24; ZNF304; MYCL; ZNF7; WWTR1; ID4; FOXJ3; NR1D2; ZNF589; REPIN1; ZNF493; SOX21; BRWD1; ZNF696; ZNF34; UBE3A; NR3C2; BRIP1; HOXA1; ZNF222; MYT1L; NKX2-1; ZNF85; LHX3; ZBTB43; FHL5; KLF2; MYB; JUNB; ZNF134; DACH1; ETS2; TFEB; SOX3; WWP1; OVOL1; MLLT10; IRF5; ZNF506; TCF7; NR3C1; KLF13; ZNF350; EN2; BRCA2; ZNF227; PITX3; ZNF586; NFX1; ZNF813; ZMIZ2; SMAD6; ELF5; LHX1; TOPORS; ERF; ZBTB6; SUV39H1; ZNF394; MTF2; TCF21; IKZF4; ARRB1; ZNF189; ZBTB25; KLF10; CD3D; ZSCAN2; ZBTB3; NRL; ZNF573; NR5A1; ZNF10; TFCP2L1; PAWR; SMAD7; ZNF16; NRBF2; CEBPA; NR5A2; NPAT; IRF1; SPI1; HMG20A; ZNF22; PRDM14; LEF1; ZNF623; ZNF267; ZNF91; ZNF236; ZNF93; NEUROD1; ZNF329; TAF1; HESX1; ZNF710; CBX7; KDM5A; GATA2; ZSCAN18; ZNF254; LIMD1; ZNF587; ARID3B; ATF7IP; PIAS1; ATOH1; CHD7; TXNIP; SCAI; TFDP2; KDM5C; IKZF5; CBFA2T3; GMEB1; ERG; FOXH1; ZNF234; WDHD1; KDM4A; SSX3; EGR3; NR1I2; NFATC3; SMAD5; PPARG; ZNF473; ZNF257; INSM1; ZNF419; BBX; YBX2; TMF1; FOXJ2; ZNF45; ZNF550; MAP3K10; ONECUT2; ZNF8; NHLH1; HDAC11; ZNF75D; ZNF223; ZNF770; ZNF3; SKI; ORC2; BAZ2B; NFAT5; CHD1; ZNF671; ERBB4; DYRK1B; MNX1; CREBZF; SFMBT1; ZNF33B; TBX3; SATB2; FOXC1; PRDM1; LYL1; ETV6; ZNF614; ELF2; TRIM33; APBB1; MEF2A; ZFP30; SRF; ZNF571; SIX6; MAPK8IP1; ZFX; RELB; ZNF175; BRPF1; RBBP5; SSX1; TAF4B; SNAPC4; NR6A1; ZNF211; HR; ZNF235; ZNF217; ZNF117; HOXD13; ZNF140; NLK; TOX3; ZNF250; CRTC1; ZNF292; ZNF200; ZNF391; NEUROD2; KLF5; HNF4A; NR4A1; ZNF574; MZF1; ZNF430; FEV; ZNF557; ZNF282; RFX1; KMT2D; DNMT3B; POU2F1; TLX3; SUV39H2; ZNF446; ZKSCAN3; BLM; CHD2; TDRD3; ZNF682; ZNF14; PRDM5; BACH1; TCF15; ZNF264; SATB1; TFAP4; PROX1; ZNF184; ADRB2; ZNF362; RREB1; BATF; PSPC1; TGS1; ZNF778; TCFL5; FOXA2; KAT7; GRHL2; NFATC1; CDX2; PLAG1; GCM1; LMCD1; EP300; NEUROG1; ZBTB20; ZMYND11; PIAS2; EMX1; SMAD3; FOXI1; THAP10; EZH1; FOXE1; ZEB2; ZNF263; REL; SNAI1; E2F5; NEUROG3; SFPQ; JARID2; FOXJ1; TBX2; GLI1; BCOR; WHSC1L1; THAP9; DNAJC1; ZNF107; CREB1; NRF1; CCNT1; RBPMS; ZNF529; ING2; FOXN3; SRY; CHAF1B; GFI1; PAX6; MED7; RBL1; KMT2B; PSMC3IP; STAT5A; TAF4; CIITA; ELF4; NKX2-5; ZNF669; CUX1; ZNF440; ZKSCAN1; POU2F3; ZNF253; CIC; LHX2; IRF6; ZNF225; PPARGC1A; BPTF; ZFP2; ZNF423; E2F8; ZNF143; SHOX; STAT5B; ZSCAN31; ZBTB48; NFYB; MED14; NFIB; DAXX; AIRE; CREB3L2; TCF7L2; HNF4G; ZNF468; ZNF226; BNC1; CRYM; TAF1A; SIX1; DLX2; FOSL2; CENPB; CREBL2; RORA; ZNF536; ZNF667; DDX54; HIC1; HOXB13; KLF9; MAFB; SMAD4; TOX; YEATS4; EGR1; OLIG2; BCL11A; HABP4; MECP2; TP63; EGR4; TOB1; NCOA1; ZNF665; IRF2; GCFC2; PNRC1; MDM4; SOX5; AFF1; YAP1; ZNF331; ZFP36L2; NRIP1; ZNF212; ZNF44; BRCA1; ANKRD1; ZNF239; CNOT3; ZBTB7A; ASCL1; PRRX1; CAMTA2; ZNF652; STAT6; BHLHE41; ZKSCAN4; POU5F1B; RCOR3; SP2; JAK2; FOS; CAPN15; PITX2; ZNF177; ZNF426; NUP62; HINFP; ZSCAN32; POU4F1; NFKB2; TFEC; JUP; NKX3-1; IRF7; PATZ1; KAT6B; HES1; IKBKAP; BMI1; EPAS1; CRY1; MEOX2; NR1H2; PAX5; BRD2; ZNF84; ZNF384; TFAM; NR2F1; ARNTL; CCNC; ZNF654; ATF1; CAMTA1; FOXF1; AGO2; CBX4; ARID4A; TAF9B; CARHSP1; CNBP; ID3; HOXA5; KLF4; SALL1; ETV1; RNF138; BASP1; EZH2; HMGA1; ZNF131; PBX3
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