Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57179	Huperzine-a	GSE92742	SKB	Human	24h	10uM	EID0304

Response Information :

Types	Number	Response transcription factors
Up-regulation	409	NFE2L2; GTF2A2; SIX2; CBFB; TSC22D3; DRAP1; MECOM; ARID1A; TADA3; PAX8; SMARCA5; TRIM16; GMNN; TFAP2A; RFXANK; ARNT2; HOXB6; TRIM22; RBFOX2; PMF1; PFDN5; CREB3; PCGF2; DEK; TAF6; PARP1; YEATS2; BRD7; HMGB1; RERE; MITF; SMARCB1; RUVBL1; TP53; SMARCA1; FOXK2; TCF25; BAZ1B; HOXB3; MDFI; SMARCC1; HDAC9; PA2G4; AES; ENY2; TFDP1; TULP3; MED15; RHOA; GTF2IRD1; ATF6; CDC5L; FHL2; RELA; SSRP1; JUN; FOXO3; SMARCD3; PIAS3; CTR9; PCBD1; TULP4; DNAJC2; RNF141; ZFP36L1; HIF1A; MED24; ZNF593; MYC; CHD8; ZNF692; TCEA1; MED16; DPF2; SOX2; CCNH; RNF10; MEN1; MEIS1; MAGED1; KAT2A; WDR77; HOXA11; HOXB2; FOXM1; TRAK1; ILF2; SREBF2; TCEB2; SREBF1; SP100; TCERG1; GTF2A1; CARM1; ITGB3BP; TGFB1; MTDH; BRF2; ERCC3; ZNF512B; MLXIP; CDK7; NSD1; MNT; YBX1; RUNX3; LDB1; MDM2; HOXB7; PSMD9; AIP; SP3; MYCBP; SUPT4H1; SHOX2; HDGF; VEZF1; STAT1; PRKDC; LZTR1; LOXL2; BACH2; SNAI2; POLR2A; XBP1; RBBP8; JUND; TCEA2; DEAF1; UBE2L3; ASXL1; HLTF; USP21; ZNF580; WIZ; TRRAP; SOX12; KAT5; CTBP1; HMGXB4; SAFB; VGLL4; SUB1; ZNF195; PEX14; GLI3; ZNF816; ATF2; PDLIM1; SPDEF; TRIM28; ZNF768; GTF2F1; ARL2BP; ETV5; PRPF6; CBX5; DLX5; HMGN3; EHMT2; TGIF1; PIR; RBM39; APEX1; NOC2L; ZNF133; TRIP6; KLF11; HDAC1; CNOT2; CBX6; SIN3B; SMARCA4; PCGF1; ZHX3; XRCC6; COPS2; POLR3C; SUMO1; ZNF205; MED21; HMG20B; PSMC3; SETD2; CNOT1; RBBP7; NCOR1; YBX3; PHF20; TAF9; TAF1D; MMS19; PBX1; UBE2I; RAN; SUZ12; TAF10; TSG101; PEG3; TBL1X; RBPJ; EYA2; SMARCE1; HOXD1; AATF; CEBPA; E2F6; LIN28A; USP22; TCF7L1; ZMYND8; NFKB1; IFI16; KDM5D; NFE2L1; TAF7; STAT2; SSBP3; ZNF528; HDAC5; NFIL3; IRF9; SMARCD1; PLAGL2; MBD2; HOXB5; CDIP1; RBBP4; MED4; MED25; PHF1; TLE2; E2F3; VPS72; ELK1; COPS5; PHF8; SLC2A4RG; CSDE1; RUVBL2; EHF; FOSB; ECD; ZNF532; SOX17; NCOA3; ELF3; ATF3; TRIM29; SETD3; UBP1; PTTG1; GMEB2; MSX1; BNC2; CTNNB1; RRN3; HDAC6; STAT6; FOSL2; CBX3; BTF3; TCF4; RB1; NFIC; USP16; ZNF552; ZNF232; HIF3A; TCF12; ZBTB17; ZNF83; POU5F1B; NR2F6; DMTF1; TRIB3; MTF1; CIZ1; DDIT3; EDF1; ATF5; NCOA6; CITED1; ZNF268; SP110; TSC22D1; ARHGAP35; PREB; NCOA2; TEAD1; NEDD8; HOXC10; NAB2; THAP7; NONO; AR; PLAGL1; LITAF; ZBED1; CREM; SUPT6H; DNMT1; ABT1; TCF3; PRMT2; CREB3L1; TCF20; GATAD2A; TOB1; HEY1; EMX2; CALR; NELFB; FOSL1; SMARCD2; SP140L; ZFHX4; CCNE1; HDAC2; YAP1; CDK8; NPM1; SND1; NFYC; KAT8; HHEX; FOXD1; SAFB2; HMGA2; ESR1; CITED2; AHR; TBPL1; SNW1; ZZZ3; RBPMS; MEIS2; DR1; CEBPB; ZNF415; PPARD; FLNA; PUF60; HCFC1; HBP1; TWIST1; SCAND1; CHD4; FOXO1; WT1; SUPT5H; KAT7; HSF2; MAZ; ZSCAN18; CREB3L2; TSC22D2; SOX4; HSBP1; PIAS4; MYBBP1A; DDX5; YWHAB; ZIC1; FUBP1; NR4A2; BCL6; YEATS4; KAT6A; CEBPZ; ETS1; TFAP2C; ZBTB38; ATN1; IRF7; THAP4; TTF2; SMARCC2; SALL2; RYBP; E4F1; BRD4; PMS1; PAX5; ERBB2; NFKBIA; ZHX2; HOXC6; CERS6; TLE1; HOXA10; CCDC59; PSIP1; FOXC1; CTBP2; ZNF544; BIRC2; ENO1; OSR2; CDK2; CEBPG; SALL1; PRRX1; CNBP; PBX3; ACTL6A; ZMYM2; CREG1; HTATIP2
Down-regulation	437	BCL11B; MYB; GATA6; IRX5; ZNF227; ZNF124; ZNF180; MNAT1; OVOL1; NRBF2; ZNF510; BRWD1; LHX6; GATA3; INSM1; LHX3; UBE3A; SOX21; EN2; IKZF1; ZNF112; DBP; ZNF22; ZNF7; ZBTB6; CSDC2; TAL1; ZNF189; ING1; TFEB; ZNF506; ZNF257; SPIB; ING3; SMAD6; ZNF778; EGR2; SRY; ZSCAN16; CBFA2T3; ZNF589; ZNF34; SNAI1; TCF21; BRCA2; FHL5; ZNF571; ERG; NR5A2; KLF10; ZNF551; TCF7; SOX18; NR3C2; FOXJ3; VGLL1; PIAS1; ZNF493; ZNF235; HOXA1; MYCL; SATB2; RXRG; ZBTB43; ZNF443; NFATC1; ZNF764; WWP1; HLF; NR3C1; ZNF586; NEUROD2; ZNF473; MYT1L; ARRB1; ZNF254; TFDP3; SSX3; ZNF85; E2F2; NPAT; ZBTB44; YAF2; EGR3; CBX2; LHX2; SKI; ATOH1; ZNF711; ZNF10; ZNF16; FOXH1; LHX1; ZNF250; ZNF556; NEUROD1; ERF; LYL1; BRIP1; ID4; ORC2; TLX3; ZNF573; ZNF222; EGR4; ZNF550; SOX3; NR1I3; PRDM14; ZNF710; ZNF304; ZNF75D; ZNF350; ZNF324B; BATF; NR5A1; LIMD1; SUV39H1; GCM1; NCOA1; ZSCAN2; ZNF267; ZKSCAN3; KLF1; KLF2; ZNF234; GFI1; PITX3; GMEB1; REL; ZNF695; SRF; PRDM1; ZNF236; TAF4B; DOT1L; THAP9; ZNF223; EMX1; HOXC8; MLLT10; ZNF671; TAF1; MAPK8IP1; ZNF200; SIX6; FOXD2; NR1D2; TOX3; PAX7; IRF5; GATA2; JAK2; ETS2; ZNF696; ZNF343; FOXJ2; ZKSCAN1; PRDM10; ZNF253; NR2E1; ZNF211; TFDP2; MNDA; ONECUT2; ZNF770; IKZF4; DACH1; CHD1; ARID3B; ESRRB; SMAD5; PRDM13; ELF2; KDM5A; HDAC11; POU2F3; RFX1; FOXI1; RFX2; ZNF292; PLAG1; NKX2-2; BLM; ZBTB3; MAP3K10; POU3F3; ZNF682; NRL; ZNF721; TEF; ETV3; ZNF93; ZNF45; SSX1; MBD1; MEF2A; TFAP2B; MTF2; SCAI; MAK; NFX1; ZNF467; BAZ2B; IKZF5; SFMBT1; ELF5; ZBTB25; ZNF8; ZNF391; GRHL2; HOXA3; NEUROD4; DCC; EP300; SPI1; BCL11A; BTG1; PROX1; ZNF177; ASCL1; ZNF174; SNAPC4; MNX1; ZNF134; HOXB8; ZNF184; ZNF33B; SHOX; HR; HES2; NKX2-8; NKX2-1; ZNF623; ZNF442; EZH1; GATA1; ZNF225; ARNTL; HNF4G; TULP2; ZNF557; CHD2; ZNF263; PGR; ZFP2; NHLH1; MAFB; NEUROG3; FOXN1; ZNF430; HOXD13; KMT2D; MAFF; PSPC1; LMX1B; TTF1; ZFP30; SATB1; TCFL5; TDP2; NEUROG2; GABPA; PPARG; ZNF14; TBX2; CCNC; TBR1; PRDM8; MTA2; CDX4; ZNF507; NR6A1; FOXA2; MYF6; PRDM5; TAF1A; CDX1; CDX2; ZNF614; HMG20A; AGO2; SUV39H2; HOXD12; LMCD1; TFEC; ZNF143; RBBP5; CRK; HESX1; PAX6; HDAC4; IRX4; KLF6; ZNF345; KDM5C; NR1I2; RELB; SCRT1; ZNF362; KLF15; MXD1; CAMTA1; HNF4A; NEUROG1; ZFP36L2; IFNB1; CBX4; OLIG2; ZNF419; NRF1; HEY2; ZNF613; SOX11; ZNF91; ZNF175; IRF4; RLF; ZNF140; BATF3; ZNF665; CHAF1B; ZNF813; HSF1; CENPB; ZNF157; HINFP; BACH1; JUNB; GATA4; POU4F1; BRPF1; TMF1; ATF1; CIITA; KLF13; ZNF423; ZEB2; STAT5A; ZSCAN32; DNAJC1; CIR1; PAWR; ZNF440; CAMTA2; NKX2-5; JUP; CAPN15; CD3D; ZNF217; CARF; ZNF394; FOXF1; ZFX; HCFC2; CEBPD; STAT5B; ZNF667; SMAD7; MED17; CREBZF; CEBPE; CREB1; IRF3; RBL1; BMI1; CCNT1; TAF9B; CBX7; TDRD3; HMBOX1; DAXX; ARNTL2; ELF4; NFE2; ADRB2; CHD7; PURA; PTRF; TBX3; ZNF529; PITX2; MDM4; ZNF239; MEOX2; ZBTB16; TCF15; ZKSCAN4; FOXJ1; NFIB; HIPK3; POU2F2; ZNF264; ZNF165; ZNF107; E2F8; ZNF426; SUPT3H; THAP10; RXRA; DLX2; AFF2; TAF5; BRD2; ZBTB20; EGR1; CARHSP1; NFKB2; HOXB13; SSBP2; KLF9; TXNIP; TRIM33; IL16; ZNF160; MED14; BBX; BRCA1; EPAS1; ID3; TRPS1; RNF14; EZH2; KLF5; FOXG1; BCOR; SOX13; CREB5; HMGA1; HOXA5; ABL1; POU2AF1; TOX; SMARCA2; IRF8; LEF1; KLF4