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Overview Perturbagen Expression Profiles Transcriptional Responses
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Overview Perturbagen Expression Profiles Transcriptional Responses
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Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID57178 Alvocidib GSE92742 SKB Human 24h 10uM EID0304
Types Number Response transcription factors
Up-regulation 366 TFAP2A; DNMT1; GTF2A2; GMNN; DRAP1; HDAC9; ARID1A; ARNT2; TADA3; MECOM; XRCC6; RHOA; SREBF2; TRIM16; RBFOX2; HMGB1; TAF6; RFXANK; PMF1; BRF2; ATF6; HLTF; RUVBL1; NFE2L2; MEIS1; SIX2; DEK; MYCBP; PFDN5; JUN; CREB3; VPS72; CDC5L; HDAC5; RING1; SOX2; MED15; MEIS2; HEY1; ILF2; NOC2L; SMARCA1; TGFB1; ZNF133; PCBD1; GLI3; TFDP1; HMGXB4; PA2G4; ENY2; RBBP8; SREBF1; SSRP1; LZTR1; YEATS2; TWIST1; PEX14; HOXB3; ITGB3BP; EHF; HOXB2; RERE; HOXB6; TCF25; HOXB5; PIAS3; FOXM1; PSMC3; PDLIM1; SLC2A4RG; TCEA2; TSHZ2; ESR1; ATF2; SUPT7L; KLF7; PBX2; CCNH; TCEA1; RUVBL2; RELA; UBE2L3; TSC22D3; ARHGAP35; MSX1; ZBTB17; PHOX2B; PRKDC; VDR; POLR3C; ZNF768; LDB1; ETV5; WDR77; SMARCB1; MDFI; HDGF; OVOL2; PSMD9; MED24; HOXD1; ZNF415; ATF3; HLX; MITF; GTF2A1; MED21; KAT2A; CHD3; SNAI2; MED25; NR4A2; ACTL6A; ZNF816; PRMT2; FOXK2; TULP3; PIR; SP100; PARP1; SMARCD3; BNC2; HIF1A; AR; SUPT4H1; PRPF6; THRA; ZNF512B; SUPT6H; SMARCA5; PCGF1; WIZ; CALR; MED23; CHD8; RNF10; EHMT2; MED16; KAT5; ARNT; AIP; EYA2; ZNF593; CEBPA; SMARCD1; HAND1; NCOR1; SOX17; ZNF692; SMARCC1; MTDH; PBX1; THAP7; GTF2F1; PITX1; ENO1; TRIM28; BRD7; CNOT2; RUNX3; NCOA2; SETD3; YBX1; SUMO1; RXRB; TAF11; CERS6; IRF6; ZFPM2; NFIC; SUB1; NAB2; SALL2; EYA1; ZFHX4; SHOX2; PHF1; RRN3; NFE2L1; ERCC2; TBPL1; ERCC3; HOXA11; PLAGL1; MDM2; WT1; NEDD8; TCEB2; EGR1; CBX5; RNF141; AHR; DLX5; NONO; CREBL2; C1D; NFATC4; ACTL6B; TRAF6; LITAF; RNF2; PKNOX2; ZNF544; ZNF268; STAT2; CD3D; HDAC6; CLOCK; SSBP3; BACH2; RBPJL; TRIM22; MKL1; HIPK2; CTR9; ZNF358; NOCT; FOXO3; ZNF76; NFIX; AES; SP2; HIF3A; CREG1; ZFP36L1; HOXB7; THRB; HDAC3; ZNF580; KLF11; EVX1; MYRF; ESRRG; TRIP6; CSDE1; ATN1; RBBP7; VGLL4; RAD21; DNAJC2; TRPS1; ARL2BP; NR0B2; POLR3F; TRRAP; ZNF83; PPARD; RSF1; ETS1; ZSCAN9; SP140L; TCERG1; HMGN3; ISL1; PPP1R13L; RFC1; MED20; MYCN; TRIB3; ST18; CNOT6; PTTG1; SIN3B; ZNF136; MED4; MED12; ZNF117; FEZF2; TOX4; NELFB; RB1; NR2F6; USP21; ZNF264; TDP2; USP16; COPS5; PCGF2; CDK2; APEX1; MYNN; ZNF205; SMARCC2; RAN; TOX; PNRC1; EWSR1; BTF3; NCOA3; ELF3; SP3; SETDB1; ZNF688; MAZ; TRAK1; SPDEF; TP53; BCL11A; ELK1; MYBL2; TFCP2; HDAC1; KAT8; ZNF532; TTF2; MAGED1; ERBB4; ZNF611; ZNF528; CARM1; NR0B1; PGR; MYC; FHL2; CIC; CNOT3; TSG101; SETD2; MXI1; FOXD1; IFI16; ZBED1; MEOX1; HMGB3; NR1H3; IRF9; EDF1; BCL6; STAT6; HMGXB3; STAT4; NR4A3; YBX3; SMARCD2; RBL2; PIAS4; CTNNB1; FOXA1; ZNF331; TGFB1I1; CTBP1; CBX6; HBP1; STAT1; NR4A1; MYCL; MYT1; ZBTB38; CCDC59; FOSB; ZNF274; L3MBTL1; TSC22D1; HDAC2; USP22; KAT2B; CEBPG; ZNF12; JUND; RBPJ; CEBPB; ZEB1; HIRA; YWHAB; EMX2; CITED2
Down-regulation 504 ZNF227; FOXJ3; MNAT1; BATF; NRBF2; KLF2; LHX6; ZFP36L2; EN2; CBFA2T3; ING1; ZNF510; MYB; BCL11B; UBE3A; ZNF263; RREB1; ERG; BRCA2; LHX1; RXRG; SPIB; CSDC2; NFATC1; GATA6; ZBTB6; ING3; MED1; LIMD1; ZNF189; IKZF1; CDK7; ZNF7; TAL1; WDHD1; NANOG; BRWD1; FHL5; SUV39H1; SIX1; KLF6; HLF; NPAT; YAF2; SOX21; ZBTB25; TAF1A; MTF2; PIAS1; ZNF257; ZBTB7A; BRIP1; BRPF1; CHD1; ZNF93; BACH1; ZNF506; ZNF423; ZNF234; ZNF770; FOXE1; NFYB; DNAJC1; SIAH2; ELF5; NFATC3; KDM5A; PITX3; TRIM24; MYT1L; PIAS2; MBD1; KMT2A; LYL1; SNAI1; PAWR; THAP9; MYF6; RFX7; FOXN3; ANKRD1; GFI1; ZHX2; IRX5; FOXC1; NR3C1; ZNF443; TSC22D2; NR1D2; ZNF236; ABL1; ZBTB3; ZSCAN16; POU3F1; ZNF573; GATA1; NEUROG3; PPARG; KLF1; E2F2; NFIB; NFX1; MAPK8IP1; PREB; ZNF84; MLLT1; LPIN2; ZNF34; ELF1; LHX3; MNX1; ZNF586; ZIC1; KAT6B; CHD7; POU2AF1; POU3F3; CHAF1B; BRD3; PROX1; IL16; ZEB2; ELF2; NCOA1; RFX1; TFAP2B; ZSCAN2; HDAC11; HES2; KDM4A; PSMC3IP; GABPA; ZNF85; ORC2; WWP1; HIC1; ZBTB18; ETV6; IKZF5; CNOT1; HOXC6; MLLT10; RBL1; TAF1; ZNF174; AGO2; TLX3; SALL1; PATZ1; NKX2-1; ZBTB40; SRY; NR5A2; PPARGC1A; ZNF24; IRF5; ZNF764; ZNF217; KLF4; OVOL1; TBX3; ING2; NEUROD1; MAF; SNAPC4; ZNF202; SMAD3; GSC2; SATB2; ZNF343; TADA2A; PSPC1; DAXX; BCOR; ATOH1; CBL; HOXD12; BLM; ZNF75D; TDRD3; ZZZ3; ZNF696; NEUROG2; ZNF778; TBL1X; SOX10; PURA; BANP; FOXN1; REXO4; ARID3B; ZBTB24; NRF1; TBL1XR1; MGA; HMG20B; GATA2; TCF7; ZNF222; ZNF165; DOT1L; POU5F1B; ARID4A; DNMT3B; HOXC4; PRDM8; ZBTB1; ZNF225; SMAD9; TBL1Y; HOXB8; NUP62; POU4F1; ZBTB44; UIMC1; SHOX; PAX7; HEY2; ZNF493; ZNF682; ARNTL; APBB1; ZNF91; AFF1; FOXB1; ZNF292; MAP3K10; KDM2A; FOXD3; KLF3; ZNF672; ZNF614; LMCD1; ETS2; E2F3; TBX2; ZNF675; MDM4; SCAND1; ZNF430; JAK2; ONECUT2; TAF5; FOXJ2; BBX; NKX2-8; ZNF45; ZNF239; TBP; REST; PRDM12; RNF111; ZNF180; DDX54; USF2; SIX6; EMX1; NKX2-5; SFPQ; IKBKAP; TGIF2; ZNF143; SUV39H2; ZNF157; HOXD13; ZNF267; ZNF391; EN1; FOXJ1; FOXN2; POU4F3; CRY1; RFX2; KLF13; HOXB9; CDX4; ARNTL2; ZNF41; CRK; PTRF; POU3F4; TEF; EGR2; CCNA2; PPRC1; DBP; POU2F3; ZNF324B; HOXA1; HCFC2; ARRB1; ARID3A; DYRK1B; TCFL5; ERF; CHD2; UTF1; OLIG2; SOX14; KLF10; AATF; ZNF780B; TFDP2; MYBL1; REPIN1; MEF2A; SMAD7; NR5A1; PITX2; TFEB; MTA1; ZNF460; CAPN15; NR1H4; BAZ2B; PRDM10; LHX2; PHF20; TCF15; ZNF16; HNRNPD; NFRKB; WWC1; PML; VHL; PLAG1; PRRX1; SAP30; ZNF250; ZNF253; SMAD6; EZH2; CBX2; SKI; TOPORS; SCAI; RELB; POU2F2; TAF9; ASCL2; ZBTB14; ID2; ZNF329; ZNF613; ZNF112; TAF7L; IRF4; NR2C2; ZNF200; BIRC2; SMAD4; AEBP1; CREB3L2; BHLHE40; NR3C2; ZNF721; MYOD1; MEOX2; ZNF492; ZNF446; SSX3; ARID4B; EHMT1; HNF4A; KLF9; TCF3; JARID2; ZNF711; MAFB; DLX4; ZNF124; PAX6; RLF; HMG20A; PRDM1; RBBP5; GMEB1; HEYL; ADRB2; TCF12; XBP1; GATA4; NHLH1; NFE2; BTG1; ZNF184; BAZ1A; BRD2; ASCL1; HR; ZNF440; ZNF813; RORA; NR1I2; SMARCE1; ZKSCAN3; ZBTB16; NCOA6; HOXA7; ZNF419; SPI1; TOX3; STAT5B; TAF12; BASP1; DACH1; FOSL2; SERTAD2; ZNF551; SATB1; TAF4; NFKBIA; SMAD2; ZNF354A; SOHLH2; EGR4; ZNF175; ZNF410; TGIF1; CREB1; TMF1; FOXA2; PAXBP1; HMGB2; CAMTA2; STAT5A; PRDM4; BRCA1; TFE3; EP400; BPTF; MLXIP; ELK3; CCNT1; CREBZF; PHIP; RARA; NLK; POU2F1; BMI1; ZSCAN32; TCF7L2; EP300; ERBB2; WWTR1; NKX2-2; ZNF557; ZNF281; DDX5; TERF2; RNF138; TAF10; KMT5A; CEBPZ; IRF7; RBM14; ADNP2; ATF4; ATF1; ATF5; ZNF32; HSF1; FUBP1; TLE1; ZFX; ELF4; CAMTA1; CDX2; PQBP1; TXNIP; NRIP1; HINFP; ZNF177; KDM4C; SMAD1; KLF5; RBPMS; EPAS1; SOX11; NR2F1; HOXC10; HIPK1; RNF14; KDM5B; HES1; RBBP4; CBX4; CEBPD; UBE2I; ZNF226; ZNF148; SPEN; HHEX; NR2F2; CRYM; HOXA5; SMARCA2; ETV1; ID4; HMGA1; HOXB13; ZBTB20; ID3; ZNF131
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