Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57172	Treprostinil	GSE92742	SKB	Human	24h	10uM	EID0304

Response Information :

Types	Number	Response transcription factors
Up-regulation	357	SOX2; ARID1A; GTF2A2; FOXO3; ARNT2; SMARCC1; DNMT1; TADA3; TULP4; MYBL2; HOXD10; CD3D; KLF1; HMGB1; KLF11; MYB; DRAP1; MITF; NFKB1; MAFG; PMF1; STAT5A; KLF7; CTR9; FOXO4; ZNF195; HOXD11; RUNX3; HOXA11; HSF4; BCLAF1; CITED1; SAFB; SUPT4H1; CDX1; RNF10; RYBP; TRIM28; MED23; RHOA; LDB1; CHD7; ZFY; VEZF1; TCF15; MLXIP; NR4A2; BARX2; ACTL6B; FOXK2; MED13; RBM39; MMS19; DACH1; KMT2A; ZNF646; HAND2; RERE; ARID3B; PRPF6; PCBD1; BRD7; SREBF1; MYOG; KDM5D; ZMYND8; NKX3-2; NOC2L; CXXC1; HOXD13; SP140; HMX1; GATA1; TSG101; ETV4; TP73; VGLL4; ETV7; GCM1; GBX2; YBX1; GTF2F1; APBB1; TCEB2; RBPMS; DPF2; PARP1; SNAI2; STAT4; CASZ1; FHL2; HDAC1; MXI1; OSR2; WNT4; ZNF408; TGFB1I1; ASXL1; XRCC6; IRF1; TAF12; CHD4; FOXA2; PKNOX2; RELA; TCF25; SND1; ZNF266; ZFPM2; HAND1; KLF15; CDK8; PAX9; SP3; VGLL1; SIX2; HOXD9; CBFA2T2; MTA2; ENY2; RUVBL1; ZNF131; MEIS1; PAX3; ZBTB40; HLTF; PIR; SMARCE1; NCOA6; DDIT3; CREB3; ARID5A; TCF21; HMGB2; ATOH1; PRMT2; KDM4C; AFF1; RBBP7; GTF2A1; CIZ1; ZNF446; LZTR1; HOXB5; TRAF6; PA2G4; TRIM24; FOXB1; TBX21; ZEB1; EZH1; CSDE1; HOXA6; YBX3; HMGB3; BTAF1; ELF3; ZNF473; BATF3; ZNF688; USP16; ZNF410; TRIM22; HDAC7; ZNF532; ZNF516; LITAF; POLR3C; HIF1A; PGR; ETV2; NKRF; E2F4; ZBED2; CREG1; TULP3; ZBTB16; TLE2; TBX10; SNW1; RBPJ; TCF20; TGIF1; APEX1; INSR; EVX1; HOXA3; NKX6-1; SMARCD3; TBPL1; ZFHX2; NFE2L1; SOX21; PSMD9; AFF3; RNF138; PFDN5; PEG3; EP300; ARID4B; HOXB7; ZNF224; PTRF; ZXDC; IRF6; GFI1B; TAF1D; HOXB6; SOX15; MECP2; HOXB3; LHX6; ZNF324; ZNF816; FEV; TSC22D3; SATB1; DEAF1; CEBPB; DMTF1; ITGB3BP; MAF; MBD2; PRKDC; MTA1; PRDM8; HIPK2; TSC22D4; GLI1; C1QBP; THAP3; ZNF394; E2F2; TSC22D2; NR0B2; GATA2; CARM1; HMBOX1; CEBPE; HMGA2; KMT5A; CTBP2; PSMC3; ZKSCAN1; ZNF331; SMAD2; ILF2; ZNF337; CREB1; BACH2; PBX1; L3MBTL1; ZNF654; SIRT2; SP140L; SP100; BCL10; MYOD1; IRF9; KAT2B; MYT1; HOXB2; YWHAB; POU2F1; ETV1; SOX13; NR2F2; ATF5; MLXIPL; NR5A2; PRDM12; HEYL; NFE2L3; TFDP2; PSIP1; HTATIP2; RNF14; KAT2A; SUPT6H; DDX5; TCERG1; SMARCA1; ZNF611; NANOG; NR0B1; NCOA3; HDAC9; STAT1; BTF3; UBTF; AEBP1; MED24; ZMYM2; SMAD4; SETD2; TRIB3; MYCBP; CREB3L2; ADNP; FOXF1; FUBP1; MYCN; RELB; ZNF281; ZNF232; BLM; SAP30; PIAS3; NR1I2; SMARCB1; BAZ1A; ARNTL; JAK2; ZNF83; ISL1; ZBTB38; SMARCC2; MEIS2; SIRT7; MYC; ZNF593; AES; MEOX1; TAF9; CDX2; ING3; SCAND1; HOXA10; BIRC2; ADRB2; OLIG2; SOX11; CREM; PAX5; ETV5; NPM1; CDK7; TP63; ZHX2; EYA2; ZMIZ1; HBP1; CEBPD; ZBTB20; MAX; KDM5B; NR2F1; NR4A1; IFI16; ZNF160; HES1; HOXA5; MSX1; ELK3; HDAC2; BTG1; PPARG
Down-regulation	442	ZNF112; FOXJ3; ZNF180; IRX5; C1D; MECOM; ERF; NRBF2; ZNF124; ZNF764; GTF2IRD1; HLF; TAF11; NFAT5; GATA3; SMAD6; ZNF7; TFEB; EGR2; TOPORS; BRWD1; ZNF227; BRIP1; ZNF254; MTF2; ZNF257; NFATC3; TEAD4; CENPB; ZNF107; ZSCAN16; ZNF117; SUPT7L; FOXM1; REXO4; ZNF586; ZNF573; BAZ2B; ZNF263; TAF1A; ZNF239; MED1; ZNF432; ZNF329; ZNF468; ZIC1; SUV39H1; ZNF32; ZNF85; RUNX1; ZSCAN31; SAP18; SRF; LPIN2; KDM5A; ZNF443; NCOR2; LEF1; CEBPA; PLAG1; ZNF623; KLF2; HOXC4; HOXC6; TFCP2L1; PPP1R13L; MYBL1; TGFB1; ZNF529; MEOX2; BACH1; POU4F1; JUNB; ZNF236; SIX1; ZNF682; ZNF493; ZNF550; FOSL2; PSPC1; ZNF84; PBX2; SERTAD2; ZNF675; FOXO1; THAP10; GLI2; GCFC2; ZBTB6; ZNF184; KLF12; ETS2; GTF2I; WDHD1; E2F3; ZNF350; FOXJ2; MLLT10; ING1; PSMC3IP; ZNF222; ZFP69B; ZSCAN2; REPIN1; SF1; MED7; DDX17; TEAD1; MXD4; E2F5; MYRF; ZSCAN18; ELF2; ZNF512B; KDM5C; ELF5; PITX2; HSF1; FOXN3; MED4; ORC2; CAMTA2; HOXC5; ID3; PDLIM1; ZNF304; CREBL2; NFATC1; SNAPC4; VDR; MED27; THAP9; FOXC1; MYCL; CTBP1; ZBTB18; ZNF189; NR3C1; ZNF45; ZNF510; CAPN15; SPIB; EGR3; YAP1; GMEB1; NELFB; PAWR; HOXC10; ZNF33B; NAB1; TSC22D1; HCFC2; HIPK3; TAF7; BMI1; SP1; COPS2; ZSCAN12; DLX2; MGA; NFYC; FOXI1; TGIF2; NR3C2; TLE4; MBD3; DR1; ZNF770; SKI; ZNF629; RNF111; ZNF423; ZNF768; ZNF234; RBBP5; ZBTB3; FOSB; ZEB2; BRCA1; PCGF3; RFC1; RFX7; KMT2D; ZKSCAN3; ARNT; UBE3A; MEF2A; NKX2-1; THAP7; ZNF571; SMAD5; CRYM; E2F6; ZNF580; CIC; POLR3F; TAF4; SKIL; SPI1; BHLHE41; REST; ZNF576; IRF8; TRIM32; MED20; ID4; ZNF165; BBX; JUND; ZNF302; ZNF223; CDIP1; TBX2; HIPK1; DDX54; MYNN; HMG20B; LMX1B; POU2AF1; ZNF200; PRDM1; COPS5; HIVEP2; ZNF202; SUV39H2; ATF2; ZFX; TTF2; RBM14; HDAC11; TFCP2; KLF4; ING4; ZNF93; ZNF34; ZNF91; ZNF225; ZNF813; CBFB; KLF10; EZH2; ZNF8; FOXG1; RBL1; ZFP30; NEUROD1; TDRD3; TDP2; ZNF696; ZNF136; CDYL; BARX1; TRIM25; SCAI; CENPF; ATF4; ZNF14; AGO2; TFE3; SOX18; MAK; GABPA; NFATC4; SUPT3H; NR1D2; PIAS2; DNAJC1; ZNF141; PRRX1; HIVEP1; ZNF226; ZNF492; SHOX; TFEC; HNF4A; MAPK8IP1; WWP1; NR2E1; TCEA1; ZNF551; CNOT3; PEX2; TXNIP; ZNF155; ZNF669; NR2F6; ST18; DBP; NAB2; MDM4; CREB3L1; RFX1; TAF5; HSF2; SOHLH2; ZNF614; VPS72; ING2; ETV6; TBX1; STAT3; ZNF557; SSBP2; TAF4B; GATA6; UBE2I; ZNF253; TWIST1; ZNF134; AFF2; ZNF143; ZMYND11; LHX1; ZBTB14; MEF2C; CBX5; ZNF419; EPAS1; POU2F3; NR1H4; ZNF16; SFPQ; CRY1; FOS; ZNF536; PCGF2; MED6; PPARGC1A; RCOR1; CCDC59; HEY2; ESR1; CBFA2T3; TCF3; REL; ZNF672; ZNF345; EN1; ZNF44; CBX4; ZNF354A; ZNF43; TOX4; LHX2; CEBPG; ZNF292; AHR; HOXA7; TBX3; TERF1; HABP4; ZNF430; ZFHX3; NFRKB; WWC1; CDK9; FOXJ1; ZNF467; PHF20; EP400; HOXD1; IRF5; BLZF1; STAT6; PITX1; ARRB1; ZNF711; ZNF175; RING1; SIAH2; FOXA1; HMGN3; MNAT1; HSBP1; KAT8; SUPT5H; SALL2; UBE2B; ZNF146; MED21; KMT2B; ZNF24; SP2; ID1; HOXB13; MED17; ID2; KLF6; JUP; ERBB2; PNRC1; IKBKAP; SOX4; HNRNPD; TRIM33; NFYB; CCNE1; NEDD8; HMGA1; CDK2; ZNF217; HIRA; ARID4A; BCL3; CREBZF; KLF3; PHIP; NFKBIB; KLF9; CALR; ASCL1; PBXIP1; TFAM; SMAD7; ATF1; NKX2-2; CARHSP1; SOX10; BCL11A; RORA; HEY1; LMCD1; TOX; RXRA; FOXD1; CHD1; EDF1; FOXF2; SLC2A4RG; BHLHE40; TMF1; LYL1; MED14; MAFB; GTF3A; SOX9; DAXX; IKZF1; BRD4; SOX17; CITED2; MNDA