Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57170	Givinostat	GSE92742	SKB	Human	24h	10uM	EID0304

Response Information :

Types	Number	Response transcription factors
Up-regulation	419	NFE2L2; DNMT1; GTF2A2; TFAP2A; SIX2; DRAP1; RFXANK; FOXK2; BRD7; TRIM16; ARNT2; CREB3; GMNN; TADA3; PFDN5; JUN; HMGB1; SMARCA5; SSRP1; ATF6; DPF2; ARID1A; RUVBL1; YEATS2; ILF2; TFDP1; RBFOX2; ATF3; PARP1; DEK; CBFB; RHOA; GTF2F1; RELA; GTF2IRD1; HDAC9; TCF25; HDGF; TAF6; AIP; SMARCD3; HOXB3; TP53; TSG101; FHL2; ZNF593; RBM39; PCBD1; SMARCD2; SAFB; MED24; PMF1; CTR9; SREBF1; PSMC3; SMARCB1; RBBP8; WIZ; ZNF195; RERE; MYCBP; HOXA11; MEN1; TCEB2; CDC5L; ZHX3; CCNE1; USP21; MYC; HOXB6; SMARCC1; CNOT2; DNAJC2; GTF2A1; PDLIM1; ERCC3; PITX1; PA2G4; BRF2; POLR3C; XRCC6; CITED1; FOXO3; PCGF1; HIF1A; E2F6; SP100; EHF; LDB1; MED16; ZNF692; SNAI2; RNF10; HOXB2; MMS19; BAZ1B; KAT5; RAN; APEX1; VPS72; ZNF133; PSMD9; DEAF1; MTDH; WDR77; SOX2; MAFG; TCERG1; MNT; LZTR1; KDM5D; PEX14; SMARCA1; PIAS3; ASXL1; MECOM; MEIS1; CTBP1; ECD; ZNF415; ITGB3BP; TSC22D1; PBX2; HIPK2; TAF10; NFIL3; TGIF2; ETV5; MITF; LOXL2; HMGXB4; RUNX1; ARHGAP35; CCNH; CALR; TEAD1; AES; TRRAP; SP3; MAGED1; JUND; MBD2; KAT2A; SERTAD2; VEZF1; HDAC5; CBX6; CDK7; TRIM22; ZFHX4; ZNF768; CBFA2T2; ABT1; HAND1; BTF3; YBX1; SREBF2; VGLL4; SUPT4H1; COPS2; DDIT3; TRAK1; ZNF83; NCOR1; SHOX2; TRIP6; HDAC1; MXI1; NFIX; ZFP36L1; IRF9; UBE2I; MED21; TSC22D3; MLX; HEY1; PHF20; RNF141; C1QBP; ZNF232; TULP4; ZNF816; MAZ; HLTF; GLI3; CTNNB1; TBX6; FOXD1; ZNF512B; CARM1; NR2F6; NFIC; CDIP1; HMGN3; HMGB3; YBX3; THRAP3; CHD8; COPS5; HLX; TAF9; TWIST1; ETS1; PLAGL2; PKNOX2; NSD1; PCGF3; NOC2L; TGFB1; PBX1; HOXD1; MED25; TAF1D; KAT8; SIRT2; SMARCE1; EHMT2; MED15; ATF2; TULP3; VDR; ZFY; ZNF580; UBE2L3; RBPJ; ZNF358; NCOA3; ENY2; BTAF1; RARG; BACH2; ZNF652; SUZ12; GATAD2A; TRIM28; NKX3-2; CIZ1; BCL6; TCEA1; DMTF1; ZMYND8; EYA2; PIAS4; TSHZ2; ZFPM2; CSDE1; PHF8; PCGF2; ZFHX3; PRPF6; SOX9; IFI16; RING1; PIR; ZNF444; STAT2; AHR; TRIM29; HMG20B; PHF1; PHOX2B; SCMH1; PPRC1; RUVBL2; CERS6; RBBP7; SIN3B; HOXB5; SND1; ZBTB17; KDM2A; ENO1; ZNF783; MSX1; CEBPG; HDAC2; CEBPB; LITAF; RXRB; CRK; ZNF629; TLE2; TAF7; ZNF646; INSR; PREB; ZMYM2; HDAC3; XBP1; MED4; GMEB2; NONO; NFKBIA; TRIB3; NCOA6; CDK8; MDM2; CREB3L2; SOX12; HIF3A; SAP30; USP16; PTTG1; MLXIP; TCF3; SETD3; TAF11; TRIM27; RBBP4; TEAD3; ZNF611; AATF; SUMO1; ZNF136; PRKDC; ARL2BP; E2F3; SETD2; ZNF544; NEDD8; ZNF205; SUPT6H; SP140L; KLF7; RB1; ISL1; TFAP2C; NPM1; CREG1; ZNF665; TBL1X; HCFC1; FOSL1; NELFB; ELK1; PEG3; CBX3; RFC1; RYBP; TCF12; ST18; ZNF528; NAB2; HBP1; ZNF44; PPARD; HDAC6; PBX3; NFKB1; PRMT2; RUNX3; AR; CEBPD; ZNF532; CEBPA; HHEX; HSBP1; ATN1; ESR1; ZBED2; TCF7L1; BRD4; CBX5; CDK9; CREB3L1; SNW1; USP22; TBPL1; ZNF274; SF1; ZNF688; ADNP; CDK2; SPDEF; MYBBP1A; UBP1; CCDC59; SUPT5H; L3MBTL1; FUBP1; ZSCAN18; CHD4; MEIS2; NFE2L1; HOXB7; SCAND1; ETV4; SETDB1; HIC2; CTBP2; NFATC4; FOXF2; HSF2; EMX2; PUF60; SLC2A4RG; BHLHE41; YWHAB; SOX17; CNBP; FOXA1; ERBB2; EDF1; ELF1; NR2C1; NKX3-1; ZNF160; SP110; PSIP1; MAX; TLE1; MTA1; GTF3A; MNDA; BIRC2; ZBTB38; HOXA5; HIRA; HTATIP2
Down-regulation	416	ZNF180; UBE3A; WWP1; EN2; ZNF510; CSDC2; BCL11B; GATA3; ZNF227; ZNF112; GATA6; BRWD1; NRBF2; MYT1L; SPIB; ARNTL2; LHX6; ING1; HLF; LHX1; OVOL1; IKZF1; KLF2; ERG; ZNF257; SOX3; NR5A2; MNAT1; LHX3; SOX21; ARRB1; ZSCAN2; PRDM1; FOXJ3; ZSCAN16; BATF; ZNF124; ZNF236; ZNF292; HOXA1; WWTR1; ZEB2; DNMT3B; TFDP2; DBP; ZNF7; SATB2; ZNF506; ZNF34; LHX2; ZNF764; E2F2; KLF10; MAPK8IP1; TOPORS; TXNIP; PAX6; ZNF573; INSM1; MYB; IRX5; ZNF304; ZNF493; ZNF589; ZBTB6; NR5A1; ZNF551; BRIP1; BRCA2; ZNF623; ARID3B; CHAF1B; ZNF586; ETS2; ZNF711; NR3C1; ZNF267; RFX2; PRDM14; ZBTB3; SUV39H1; PPARGC1A; ZMIZ2; PAWR; MBD1; HESX1; BCLAF1; ZNF234; THAP9; NANOG; JARID2; ZNF423; NR3C2; MLLT10; FHL5; ZNF696; TRIM24; ZNF22; NEUROD2; KMT2D; ID4; ZNF473; ING3; HDAC11; EMX1; KLF6; HOXC4; SSX3; NFATC3; PIAS1; ZNF770; NEUROD1; EGR3; DACH1; ZNF254; FOXN3; CIITA; PAX1; ZNF85; POU4F1; ZNF682; FOXJ2; IKZF4; WDHD1; ZNF350; GATA1; ZFP2; BLM; ZNF556; PITX3; KDM5A; NEUROG3; BACH1; IKZF5; EGR4; NFATC1; ZNF189; ZNF235; SOHLH2; ZNF16; NR1D2; ZNF250; SMAD6; SIM1; TBR1; IRF5; ZNF75D; NEUROD6; HMG20A; NFX1; MTF2; RORA; GATA2; FOXH1; LIMD1; ATOH1; BATF3; CBFA2T3; SNAI1; ZNF45; FOXN1; RXRG; NKX2-8; SHOX; MYF6; TOX3; MAP3K10; ZBTB25; SOX18; SSX7; SIX6; PPARG; ZNF778; ZFX; ZNF184; ESRRB; BCOR; ZNF571; FOXG1; ZNF391; JUNB; RELB; ZNF343; TAF4B; POU3F3; BMI1; MAFB; HEY2; JUP; SKI; MEOX2; NHLH1; ZNF8; SRY; ZBTB44; FOXD3; EGR2; RFX1; GMEB1; TFDP3; TFAP2B; CHD7; NCOA2; CBX2; MED14; ZNF550; SCAI; ZNF222; LYL1; NCOA1; TCF21; EP300; PRDM12; ZNF223; CHD2; FOXC1; ERF; ZNF695; HDAC4; TLX1; ZXDC; DOT1L; VGLL1; LMCD1; ZNF157; DCC; ZNF443; HOXD13; HOXB8; ZNF10; ZNF507; GCM1; TCFL5; POU2F1; ZNF442; ZNF529; CBL; ZNF671; NKX2-2; TCF15; PRDM8; KDM4A; TAL1; TFCP2L1; PSMC3IP; ZNF813; ZNF253; ZNF208; THAP10; SUV39H2; KLF1; OLIG2; SMAD5; PURA; ZNF211; EP400; POU2F3; PRDM13; ZMYND11; NR6A1; SATB1; ZNF84; NR2F2; MAK; SSX1; ZNF710; SIM2; ZNF143; NRF1; TBX2; ZNF467; FOXJ1; SCRT1; ONECUT2; PPP1R13L; ZBTB43; BLZF1; ZNF200; TLX3; SALL1; KDM5C; SNAPC4; TDRD3; TFEB; NR2E1; TAF9B; PML; GABPA; ZNF613; ZNF225; TAF1A; ATF7IP; RBL1; ZSCAN31; ZNF446; HNF4A; AIRE; DAXX; TAF7L; ZNF239; ZFP30; TMF1; NR4A1; PATZ1; GFI1; HR; ZNF93; PITX2; JAK2; KAT6B; HNF4G; NRL; SPI1; NPAT; NKX2-1; TERF1; PSPC1; HIC1; MED1; NFE2L3; TLE4; ZNF175; CARHSP1; STAT5B; ZNF492; ATF1; TCF7; ZNF177; IRF4; ZKSCAN3; ZNF440; EGR1; MYBL1; HOXC6; ADRB2; FOXE1; CAPN15; BNC1; AFF2; CBX7; KAT7; CREB1; HOXC10; PGR; YAF2; MYCL; KLF9; BASP1; CAMTA1; ZNF419; IRX4; NKX2-5; TBX21; ZNF787; ELF2; GFI1B; RLF; GRHL2; ARNTL; SOX11; CREBZF; HOXA7; AGO2; ZNF329; ZNF217; SOX5; FOSL2; TBX3; KLF13; TAF4; PIAS2; DNAJC1; KLF4; IRF1; ZNF134; NFIB; YEATS4; UBTF; PNRC1; ZNF331; LPIN2; KLF5; ZNF468; ZHX2; HIPK1; ZNF226; TP63; NRIP1; EZH2; ING2; CHD1; NR2F1; ZNF140; PAXBP1; SFPQ; ZNF107; SMAD7; RBBP5; BRCA1; RBPMS; CBX4; NFKB2; MEF2A; ASCL1; TFEC; CREB5; DLX2; ZBTB20; ARID4A; FOS; SMARCA2; HOXB13; AFF1; TOX; CEBPZ; LEF1