Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57166	Propylpyrazole	GSE92742	SKB	Human	24h	10uM	EID0304

Response Information :

Types	Number	Response transcription factors
Up-regulation	394	TFAP2A; NFE2L2; ARID1A; DNMT1; SIX2; PMF1; HMGB1; RFXANK; GMNN; SMARCA5; GTF2A2; CREB3; TCF25; TSC22D3; ARNT2; ILF2; SSRP1; ATF6; DRAP1; RELA; DEK; RUVBL1; CBFB; FOXO3; HMGXB4; PFDN5; TP53; GTF2A1; SMARCA1; PA2G4; HOXA11; CDC5L; JUN; RBFOX2; FOXK2; TADA3; SMARCD3; TCEB2; PIR; AIP; RBM39; HDGF; MYC; HOXB6; LDB1; KAT5; PSMC3; SNAI2; PBX1; NFIL3; SMARCB1; CCNH; ETV5; PCGF1; ENY2; POLR3C; NOC2L; SMARCC1; ASXL1; MEIS1; DPF2; YEATS2; MTDH; SP3; SREBF2; TCERG1; SREBF1; USP16; WIZ; ZFP36L1; SP100; NFKB1; HDAC9; TBL1X; ZNF195; BACH2; EHMT2; BRD7; XRCC6; DEAF1; HIPK2; ZBED1; RUNX3; PEX14; AES; FOXM1; RBPJ; AR; ZNF580; PCBD1; EHF; MEN1; PSMD9; TAF1D; CLOCK; TRIM22; DDIT3; TAF6; CBX6; YBX1; SOX2; SLC2A4RG; NKX3-2; ZNF692; CBX5; ZNF444; SUZ12; SIN3B; ZFY; COPS2; NFYC; RING1; TULP3; LOXL2; ITGB3BP; NSD1; FOXD1; ZBTB18; VPS72; GTF2F1; HOXB2; CSDE1; APEX1; MECOM; CARM1; CALR; CHD9; CNOT2; MAZ; HIF1A; GLI3; CNOT6; DNAJC2; PRPF6; NFIX; PARP1; JUND; ERCC3; RYBP; HLX; SUPT4H1; BCLAF1; TAF9; MAFG; ZNF281; KDM5D; ZMIZ2; MYCBP; ZNF593; SSBP3; USP21; HDAC6; PRKDC; SCMH1; TBX5; PHF20; GMEB2; RXRB; RERE; WDR77; YAP1; MITF; HLTF; BRF2; CTR9; NR2F6; MEIS2; HOXB5; EDF1; MED13; FOXN2; VGLL4; ZNF408; CTBP1; ZBTB17; MED4; ZNF512B; RNF141; PQBP1; ZNF141; ECD; KAT2A; MTF1; HOXB3; TGIF2; YBX3; ZNF410; MED20; FEZF2; RB1; TDP2; NACA; SUMO1; GTF2IRD1; IFI16; TRIM16; CHD8; LZTR1; TWIST1; HMG20B; COPS5; ZFHX4; NCOR1; BTF3; ACTL6A; BAZ1B; ZNF117; ZNF132; MAGED1; NFIC; ABT1; PCGF3; CTNNB1; TAF7; SUPT6H; MMS19; ZNF544; SAP30; NFATC4; ATN1; TLE2; MAML1; RAD21; THRAP3; MED15; CHD3; FOXA1; ZFHX3; MDM2; TP73; TRIB3; FOXO1; FOSL1; SUV39H1; NONO; NKRF; RFC1; ETV4; CDK7; NPM1; NCOA3; MED12; MED16; ERCC2; CDK2; PIAS3; PHIP; ZSCAN18; CEBPB; NELFB; RSF1; RRN3; PHF8; BNC2; PBX3; CITED2; TRIP4; ST18; ZHX3; CCNE1; NFKBIA; MNT; SOX13; SOX9; SMARCD2; ZNF816; ZNF268; CCDC59; ARHGAP35; TBX1; WT1; AHR; SETD3; RNF10; HCFC1; HDAC2; TSC22D2; THRA; NR4A2; THAP7; KAT8; HOXA10; ELK4; ATF2; MYRF; ZEB1; ZNF282; TRIM27; CTBP2; ZHX2; TCEA1; RUVBL2; MXI1; INSR; BAZ1A; ZNF35; FOSB; ZNF415; ZBED2; TSG101; ZMYND8; UBE2I; HHEX; TEAD4; PATZ1; MED23; IRF9; TRIM28; MYBL2; MED21; NAB2; DDX17; EYA2; STAT6; MBD2; ZKSCAN1; BRD4; HMGN3; GTF3A; MBD4; TGFB1; ZMYM2; SIX1; KLF7; PPRC1; GATAD2A; MSX1; VEZF1; KAT6A; STAT4; TFAM; UBE2L3; RORA; SATB1; SP110; PUF60; SCAND1; SMARCC2; ZNF232; HMGB3; PHF1; HOXC10; RXRA; ADNP; ENO1; SOX4; THAP4; ZZZ3; SHOX2; ETS1; ZNF274; E4F1; CIZ1; LITAF; STAT3; ZNF12; RBL2; RNF6; BCL6; AEBP1; ZNF654; ZNF266; CHD4; ZNF528; CRK; UBTF; PCGF2; ARL2BP; FHL2; TRAK1; TGFB1I1; BASP1; ELF1; CEBPG; SUPT5H; TSC22D1; ERBB2; RAN; FOXF2; ZNF146; TRIP6; HIPK3; PSIP1; TCFL5; BIRC2; EPAS1; FOS; USP22; NFE2L1; RELB; SSBP2; TBX2; EMX2; CREG1
Down-regulation	418	GATA6; NRBF2; OVOL1; ZNF227; ZNF510; GATA3; ING1; KLF2; ZNF180; DNAJC1; SPIB; LHX6; LHX1; ZNF112; ZNF468; WWP1; ZNF696; IRX5; LIMD1; ZNF7; WDHD1; MXD1; NANOG; BCL11B; FHL5; CSDC2; ZNF236; BRIP1; ZNF764; KLF10; TRIM24; NR1D2; NR5A2; ZNF551; PRDM14; MYF6; WNT4; BATF; ELF5; FOXH1; ZBTB43; ZNF493; FOXN3; EGR2; PRDM1; DBP; RREB1; HOXD13; HLF; NCOA1; ZNF586; IRF6; E2F8; ZNF175; SOX10; E2F2; PRDM10; ZFP36L2; RXRG; IRF5; ZEB2; TCF15; NR3C1; LHX3; KMT2D; MAFK; KDM5A; IRF4; ZNF267; IKZF5; FOXJ2; EN2; ZFX; ZNF813; ZNF711; SSX1; ZNF124; ZNF234; HOXA1; LMCD1; ZNF45; ZNF614; ARNTL2; SSX3; DACH1; ZNF134; NR4A1; ZIM2; ZSCAN16; UBE3A; NR3C2; ZFPM2; TFAP2B; ARRB1; ZNF292; ZNF350; PIAS2; ZSCAN2; POU2AF1; ETS2; NKX2-8; ZNF571; ZNF446; YAF2; PRDM13; ERF; CBFA2T3; ZNF556; TOX; ZBTB6; HDAC11; MYT1L; HES2; RFX2; ZNF107; HOXC4; POU4F1; ATOH1; GATA1; BARX2; NFATC1; ARID3B; BRWD1; IKBKAP; PLAG1; ZNF550; HR; NFATC3; ZNF589; NHLH1; SIAH2; WWTR1; MTA2; CAMTA1; FOXE1; CEBPA; EBF2; BACH1; NPAT; ZSCAN5A; SIX6; ESRRB; PITX3; LPIN2; TBX3; IKZF4; MBD1; NKX2-2; ZNF85; PAX1; NR5A1; ZNF304; TFDP3; PURA; ZNF391; ZNF189; ZBTB44; BRCA2; SRY; ZNF84; CREBZF; VENTX; ZNF423; POU3F3; ANKRD1; PHOX2A; ZKSCAN3; IL16; SOX5; TBX21; ZNF276; WHSC1; PAWR; HESX1; ING4; HOXC5; DYRK1B; ZBTB14; LYL1; POU5F1B; PITX2; ZNF419; NCOA2; MYOD1; FOXN1; ZNF473; THAP9; JUNB; MYB; NEUROG3; ZNF184; NEUROD2; SATB2; GATA2; JAK2; GATA4; KLF5; DNMT3B; MAP3K10; ZNF174; SMAD5; YBX2; NR6A1; ZNF8; TLX1; TAF1; ZNF329; SOHLH2; ZNF34; KLF1; RBL1; MYCL; MEOX2; ID4; BATF3; IRF1; TFDP2; NRL; ZNF257; MLLT10; ING3; ZNF264; ZNF536; ZFP30; BTG1; HEY2; MAPK8IP1; SNAI1; EP300; EZH1; SOX3; PRDM2; EMX1; ZNF75D; GABPA; ZNF254; HOXB9; POU3F1; REXO4; ONECUT2; AIRE; CHAF1B; CNOT1; E2F5; PAX6; MYOG; RNF14; ERBB4; CARHSP1; ZNF202; NEUROG1; ARID4A; HNF4A; ADNP2; TLE4; TOPORS; HIC2; USF2; CHD7; TFCP2L1; ZNF710; ZNF506; MEF2A; DAXX; TAL1; PSPC1; ZFHX2; ZNF222; PPARG; CIC; KLF3; GMEB1; SCAI; ZNF623; EGR3; FOXL2; CDYL; AGO2; RNF4; BPTF; MTA1; SOX18; ZNF250; ZNF682; PRDM12; ZNF665; CDK9; BNC1; ZBTB25; ZFP2; ZBTB3; CBX7; PDLIM1; LIN28A; HIC1; SMAD6; CDX2; HMX1; POU2F3; ZNF200; TP63; KLF4; RBBP5; INSM1; UTF1; ZNF430; SOX15; POU2F1; GFI1B; HNF4G; RCOR1; ZNF574; ZMIZ1; ZBTB7A; ZNF613; TCF21; RFX5; SUV39H2; BLZF1; CREB5; ZNF426; EP400; SRF; KMT2A; CRY1; EGR1; NFYB; BLM; ZSCAN32; TFAP2C; PEX2; NKX2-5; TRIM29; ZNF667; TCF3; MEF2D; ZNF226; THAP10; OLIG2; SALL1; ZNF177; PROX1; HOXB13; GFI1; ZNF557; NR1H2; HCFC2; ZNF16; WWC1; CCNA2; ADRB2; CREB1; YY1; BCL3; ZNF140; ZNF211; SOX11; ARNTL; RBBP4; KDM5C; MED1; ID3; HES1; ASCL1; ZNF573; PML; SUPT3H; MAF; ZNF32; HOXC6; MAFB; ATF1; TOX3; BMI1; BANP; ETV1; TBL1XR1; SKI; BCL11A; PRDM4; HOXA4; PPARGC1A; ZNF93; NFRKB; ERG; SFPQ; SMAD7; JARID2; ID1; CCNC; ATF5; SMAD4; ZNF384; BCOR; TMF1; IRF8; ZBTB38; CHD1; CAPN15; MAX; BHLHE41; MED17; TCF7; ZNF532; TCF4; PBXIP1; SMARCA2; NFIB; HOXB7; ABL1; EZH2; FOXG1; SOX17; BBX; NFE2; TXNIP; MEF2C; NR2F2