Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57152	Treprostinil	GSE92742	PHH	Human	24h	10uM	EID0303

Response Information :

Types	Number	Response transcription factors
Up-regulation	157	HOXC6; BHLHE40; CREB5; EBF2; ZNF91; ATF1; YBX1; ZNF783; FOXD1; ATF6; CRY1; FOXO4; FOSB; BATF; SMARCA2; TP53; RHOA; KDM2A; TAF10; TSG101; HIVEP2; NRBF2; RELB; FOSL1; ZNF586; PARP1; RNF14; SMAD5; GATA4; KLF10; USP22; NCOA4; PIAS2; MTDH; MEOX2; FOXO3; PIAS3; HCFC2; HNRNPD; FOS; TLE1; MYC; STAT5A; EP400; TRIP6; NFE2L1; SP110; DNAJC1; RUVBL2; KLF4; NFATC1; ZNF189; YWHAB; APEX1; EGR1; TSC22D1; ELK1; EDF1; BMI1; PEG3; ELK3; SNIP1; SMARCA4; ORC2; TBP; C1QBP; CTR9; ENO1; MED16; ZHX3; XBP1; GABPB1; GTF3A; TRIM32; BRF2; CEBPA; PAX8; HLF; BCL3; IRF1; SMAD2; NFIC; PREB; ZNF587; CCNC; AATF; NUP62; ASH2L; ZEB2; ZNF329; CRK; KLF6; CHD4; BATF3; NKX3-1; RNF10; TRIP4; BTAF1; MEF2A; SMAD3; HSF2; MAGED1; EGR3; JARID2; PSIP1; CASZ1; HLTF; FHL2; ID2; NFKBIA; HMGN3; PSMD9; AFF1; TBPL1; TRIM24; BRD4; ELF3; ZFHX4; ARID4B; IKBKAP; HOXA5; SERTAD2; CREG1; HOXB7; STAT3; LPIN2; NEDD8; NONO; DPF2; MLXIP; TAF9; CARM1; DNMT3B; DRAP1; TRIM16; SCAND1; TSC22D2; TLE4; RBBP4; TBL1X; UBP1; RFX5; BASP1; RERE; ZBTB38; NR2C1; ID1; ZIC1; MSX1; ESR1; HDAC1; PDLIM1; ABL1; WWTR1; KDM5D; EMX2; ZMIZ1
Down-regulation	144	TCEA2; HMGA1; ARID5B; ZNF557; DNMT1; ZBTB44; E2F8; MTF2; RBFOX2; NFE2L3; GMNN; NKX2-1; ARNT2; ZBTB20; FOXM1; CBX4; MYBL1; KLF13; SMARCB1; HOXA11; GFI1; STAT4; ACTL6A; MEIS2; RAD21; TFAP2A; HMGB3; MED15; PRDM1; IRF9; TGFB1I1; E2F4; FUBP1; SMARCD1; TGIF2; SNAI2; BCL11A; ZNF580; VGLL1; AFF2; KDM5C; TAF1C; CREB3L2; ZNF235; CBFA2T2; ZBED1; CERS6; ZNF652; CTBP2; SOX18; ZNF232; VDR; MAK; ERBB4; THAP7; MED14; FOXF2; ZNF180; SHOX2; WDR77; TULP3; AEBP1; DLX2; TTF2; ZNF331; TCEA1; MXI1; ZFHX3; PLAG1; MYBL2; TDP2; SKI; CNOT3; HIVEP1; ZBTB16; ST18; SOX13; EMX1; PBX1; ARL2BP; ZNF467; CRYM; GATA6; HSF1; MED17; IRF6; EYA1; CCNH; TOX; HIC2; GRHL2; ZNF532; CDK2; ID4; LOXL2; ZNF350; ZNF423; CUX2; CALR; CTBP1; TCF7L2; CNOT6; FOXO1; ARID1A; NFATC4; LMCD1; SSBP3; SALL2; USP16; NEUROD1; CREM; GFI1B; CUX1; RBBP8; HBP1; PIR; PAX5; MYCL; TP63; POU2AF1; ZSCAN18; FOXG1; YEATS4; FOXA1; DACH1; JUP; HIRA; HOXB2; HDAC9; ESRRG; NR2F1; TFAP2C; VPS72; TAL1; IFI16; TOB1; ZNF589; FOXC1; MYB; ZNF239; NFATC3; ZBED2; LEF1; WT1