Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57129	Treprostinil	GSE92742	PHH	Human	24h	10uM	EID0302

Response Information :

Types	Number	Response transcription factors
Up-regulation	176	VGLL4; STAT5A; PCBD1; AES; HMGN3; BCL3; TRIM28; BRF2; HDAC6; STAT5B; PLAGL1; TP53; USF2; MAZ; SMARCA2; ID2; NFYC; HLF; NPM1; SUV39H1; TGFB1; ELF1; PPARGC1A; ZNF226; DRAP1; RHOA; NCOA4; ELK1; TSC22D1; FLNA; POLR2A; BAZ2B; HLTF; RBBP4; HDAC1; KLF5; SETD3; LIMD1; SMAD4; MED23; HEY1; KDM5D; TBL1XR1; AFF1; RXRB; CITED2; C1D; MEF2D; FOSL2; UBP1; BRD2; NRIP1; BATF; BRD8; SIAH2; PITX1; CUX1; DDX54; SMARCD2; MEF2A; NFKBIA; RCOR1; MAX; TSC22D3; SNW1; CBX3; RUVBL2; CTR9; FOXO3; KLF2; CTNNB1; NCOR1; FOXJ3; HDAC5; EP300; YBX1; HSF2; WWTR1; MED1; SFPQ; ATF1; NUP62; NEDD8; ZNF324; CARHSP1; SMAD7; RNF4; EDF1; MED24; SND1; CENPB; NRBF2; LPIN2; JARID2; FOXD1; ZNF148; CREG1; FOXO4; GATAD2A; ADNP; MEIS1; MAF; NONO; RNF6; BRD4; TRIP4; NAB1; MAFG; CEBPA; SMARCE1; BBX; NELFB; TRIP6; KAT6B; USP22; ZIC1; TRIM32; ETV5; PQBP1; RUNX3; IKBKAP; TCERG1; AHR; MED6; SP100; ZBTB43; SIX2; PURA; PTTG1; ZNF160; ZEB2; KLF6; BRPF1; IRX5; ENO1; SREBF1; ELK3; MYCBP; RNF10; TSC22D2; SCAND1; BCL6; MYC; CREM; TAF10; TRIM29; GABPB1; ZNF721; BAZ1A; FHL2; FOSB; HOXA5; TADA3; ID1; RLF; KLF10; ZNF91; YWHAB; APEX1; ZBTB1; TRIM16; ZBTB38; ATF4; ETS2; STAT6; ZMYND8; TLE1; SOX4; PEG3; JUP; CRK; PDLIM1; NR4A1; NR2F2; TRIM22; TXNIP
Down-regulation	159	DNMT1; MEIS2; FOXO1; ZEB1; MYRF; AEBP1; NFE2L3; POU2AF1; HIRA; BACH2; ZNF623; GRHL2; ZNF557; HOXA1; ZNF239; SMAD6; ZNF7; ZBED2; ZNF180; IRF4; SNAPC4; SKIL; POU4F1; ZNF350; ZNF215; SOX2; ARL2BP; TAF1A; ZNF835; ZFX; ZNF467; ZBTB3; LHX2; ZNF195; TULP3; ZNF74; MED20; PRDM14; FOXE1; CBFA2T2; BACH1; NFX1; TAF9B; NKX2-1; ZNF552; DACH1; SPDEF; ZIC3; ZNF682; SIX3; MED14; ZNF266; WDR77; ZNF34; SP140; SHOX2; BNC1; MGA; ZNF354A; TCF7L2; TFEB; ZNF253; ZSCAN32; MDM2; NFATC3; ZNF813; ERBB4; OLIG2; E2F8; PAX5; ST18; BRIP1; TERF2; HIC2; ZNF10; SSX1; BRWD1; BNC2; TTF2; DLX2; VDR; NFATC4; WDHD1; FOXG1; LHX3; PBX1; MYCL; AGO2; SALL2; IRX4; MYBL2; HOXB6; SPIB; ZNF423; ILF2; ZNF232; ZNF211; ZHX2; YEATS4; TBX1; HOXB13; ZNF175; FUBP1; CDIP1; TFAP2A; PHIP; HDAC9; FOXM1; ZNF589; IRF9; TCEA2; KLF13; VPS72; PBX3; LOXL2; HIVEP1; MECOM; ARID5B; HOXD1; CUX2; GATA6; RBBP8; FOXF2; ZNF415; RBFOX2; CBFA2T3; ZNF117; MYBL1; ZBTB16; PRRX1; TFAP2C; ZBED1; BCL11A; OSR2; ID3; PMS1; CD3D; PLAG1; DDIT3; ZNF83; NR0B1; RXRA; NR2F6; E2F5; BCL11B; ZFPM2; NANOG; PAWR; ISL1; SOX17; CREB3L2; LEF1; ACTL6A; IFI16; EGR1; TOX; CRYM; ZMIZ1; CCNA2