Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57114	Varenicline	GSE92742	PHH	Human	24h	10uM	EID0301

Response Information :

Types	Number	Response transcription factors
Up-regulation	96	NUP62; TCF7L2; KLF6; OLIG2; NFE2; ZNF91; CDYL; HDGF; BTF3; HOXB2; ARID5B; PDLIM1; ZFP36L2; NCOA1; KLF11; SUV39H1; DDX17; NPAT; TGFB1I1; RBBP8; ZMYM2; NR5A2; ATF4; ZSCAN18; ARNT2; RXRA; ZNF224; TBX1; EPAS1; TCERG1; SPDEF; TAL1; GATAD2A; GTF3A; ZFPM2; ZNF587; PAWR; TFAP2A; ZNF331; RAN; WT1; RNF138; PBX3; ELF4; SALL1; FOXC1; LHX2; ERBB2; ZNF93; INSR; IRF3; ZNF202; ANKRD1; ERBB4; TFDP1; ID4; ZNF83; CUX2; TDP2; SOX13; GATA6; CEBPD; PMS1; FUBP1; PKNOX2; KLF1; HOXB6; STAT4; SHOX2; CITED2; KLF7; SMARCD3; JUND; ATF3; CREG1; SMARCA1; HMGB2; MEIS2; ZNF43; BNC2; SOX17; SERTAD2; ZNF512B; JUP; KLF10; YBX3; CTBP2; RORA; GATA3; ZNF217; EMX2; FOXO1; ID3; LMCD1; TRIM29; CRK
Down-regulation	80	CCNA2; NRIP1; EZH2; USP22; HES1; MYCBP; ING1; PHF2; TULP4; MNAT1; AES; HLTF; HOXB7; MTDH; GABPB1; SREBF1; ASH2L; ING3; TBL1XR1; VGLL4; RELB; BRPF1; MTF2; SMARCA4; MED4; ENY2; PSIP1; BBX; KAT6B; ELK3; UBTF; TCEA1; USF2; PTTG1; ZNF536; ETV1; PAX6; EN2; EED; NANOG; CHD4; SOX15; TSC22D1; RCOR1; ERG; GTF2I; CARHSP1; PAX5; SOX9; MED23; NFAT5; TCF4; IFI16; MAFB; ZNF12; BHLHE41; TSC22D3; NR1D2; NR3C2; TLE4; NKX2-1; ZNF146; TRIM22; NR4A1; PBXIP1; ELF3; ATF1; HOXC6; CRYM; EGR3; SSX1; TRIM16; TFAM; EGR2; FOXF2; PPARD; NFKBIB; KLF5; FOXF1; RBPMS