Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57079	Givinostat	GSE92742	NPC	Human	24h	10uM	EID0300

Response Information :

Types	Number	Response transcription factors
Up-regulation	54	SMAD3; GATA3; COPS5; NFATC3; KDM5C; ZNF224; PRDM12; ING4; VPS72; PCGF1; SPIB; TRPS1; PEX14; ZHX2; NR0B2; NFATC1; TERF1; NFATC4; ERBB4; SIRT2; SPDEF; BANP; BACH2; BARX1; ARID5B; CBFA2T3; HDAC9; IRF6; E2F8; ATF5; LEF1; MYBL1; ESR1; HHEX; ZFP36L2; PSMC3; TP63; NFE2L2; MXI1; ZBTB20; GATA6; NFE2; JUP; BCL11A; GTF3A; MYCN; SMAD1; TBX3; ST18; MYRF; KLF9; TWIST1; SNAI2; DACH1
Down-regulation	105	HMGN3; GATAD2A; USP22; RLF; DNMT3B; TAF6; MYCBP; SFPQ; BASP1; SETD2; CREB5; FOXO3; TSC22D2; TAF10; TRIP6; SUB1; RNF10; TRIM28; TRRAP; CRK; MED1; BAZ1B; SIX2; PIAS3; ERBB2; TMF1; SMARCA4; NELFB; ZBTB11; RUVBL2; PCGF2; EGR2; SSRP1; NAB1; TFAM; KDM4A; PLAGL2; ZNF468; CARM1; BAZ2B; ATF1; PBRM1; ETS2; SP3; NUP62; NR2F2; CHD1; RELA; PATZ1; TRIM16; RNF6; ELK3; CTBP1; ZNF432; JARID2; HMGA1; CRY1; CHD9; KDM5D; BCL10; NR1H3; PHF8; TRIM22; TOPORS; ISL1; HLTF; AR; HDAC6; GABPA; SALL1; OLIG2; PAX6; RBPMS; TCF12; MEIS1; ZNF423; CTR9; KAT7; NRIP1; SHOX2; YBX1; STAT1; MAGED1; XBP1; FOXJ3; SIX1; BMI1; PBX1; MAX; ZNF131; ARID4B; HMGB3; MAF; MSX1; BIRC2; ZEB2; BRD2; ID1; ZBTB38; AHR; PTTG1; EMX2; ASCL1; HOXC6; NKX3-1