Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57070	Varenicline	GSE92742	NPC	Human	24h	10uM	EID0299

Response Information :

Types	Number	Response transcription factors
Up-regulation	70	ZNF274; GATA2; STAT4; BTF3; RHOA; CREG1; KLF11; TCF7L2; TRIM16; NFE2; MYCN; CDIP1; EPAS1; PSMC3; MYRF; PBX3; CEBPD; PCGF3; GATA6; HLX; TFDP2; HMGB3; ZNF426; CARHSP1; ZNF467; ARID4B; ARNTL2; TRIB3; SIX3; TCEB2; BACH2; KLF7; YBX3; NFATC1; CREB3L2; ID1; TFAP2A; HIRA; ATF5; ZBED2; BTG1; NFE2L3; TCF21; POU2AF1; HEY2; SP110; DLX2; MXI1; FOXF2; GATAD2A; KLF6; YAP1; SNAI2; ARID5B; JUP; TAL1; ZEB1; DACH1; FOXL2; SOX11; IRF6; ZFP36L2; SATB2; TCEA2; HHEX; HMG20B; WT1; TXNIP; KAT6A; CRK
Down-regulation	108	NUP62; MAML1; BRCA1; USP22; ZNF587; ZNF443; DNAJC2; TWIST1; ZIC1; STAT3; ZNF189; EED; MTDH; ITGB3BP; CHD1; MDM2; GMNN; PATZ1; TAF1D; NRIP1; HMGB2; EGR3; MEF2A; TGFB1; ZMIZ2; BAZ1A; TRIM22; PPARGC1A; RNF14; BMI1; CHD9; PRRX1; ZNF160; TAF7; PLAGL1; ADNP; ZNF146; ZZZ3; XBP1; TRPS1; FOXC1; JARID2; TRIM32; ETV1; EGR2; WWP1; NR1D2; SIX2; TTF2; MYCBP; BCLAF1; PMS1; ZNF226; RB1; GTF2IRD1; ZNF107; EDF1; ZNF267; DEK; NFAT5; SMARCA1; LEF1; FOXJ3; CTR9; CREB1; NCOA3; ZNF468; NR1H3; SIX1; ZSCAN18; CRYM; ZNF12; TAF10; ZNF131; MEIS1; RORA; MEOX1; ING3; KLF9; BBX; CITED2; DDIT3; CBX3; BCL6; ATF1; WWTR1; ZNF721; HLTF; FOXG1; ELK3; CRY1; HMGA1; RBPMS; IKBKAP; POU4F1; MAGED1; EGR1; SMAD3; TOX3; BASP1; DMTF1; TRIP6; BATF; ASCL1; NR4A1; ZBTB18; NR2F2; NFKBIB