Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57045	Alvocidib	GSE92742	NPC	Human	24h	10uM	EID0298

Response Information :

Types	Number	Response transcription factors
Up-regulation	118	STAT3; BAZ2B; PIAS3; IRX5; TBP; RNF111; TSC22D1; ZNF721; MAGED1; ZNF160; RNF14; CITED2; RHOA; NR1D2; CASZ1; JUN; REL; ELF2; DPF2; POU2F1; PSIP1; HMGB3; ABL1; ASH2L; MSX1; GABPB1; DNMT3B; RFX7; YWHAB; RBM14; ZNF212; CCNA2; HEY2; HIPK3; MYT1L; HSF2; DEAF1; PMF1; HNRNPD; KAT5; CTR9; BANP; ING1; NR3C2; PSPC1; NFKB1; ZNF611; TCF12; TLE2; TSC22D2; CTNNB1; ZNF652; NKX3-1; TXNIP; TOB1; RBBP5; CTBP2; RBPMS; ZMYM2; MKL2; HMGA2; PIAS1; SMARCA5; SIAH2; TCF4; ZNF430; KLF6; BAZ1A; RBPJ; FOXO1; RUVBL2; ZNF551; NCOA4; EYA2; MAFF; TBL1XR1; ELF1; SAP18; NEDD8; MEOX2; RBBP4; SMAD4; SALL1; SMAD5; EZH2; SMAD1; ZKSCAN1; MED6; LITAF; ZNF44; NLK; TRIM22; CRYM; SPEN; MNDA; ZNF665; NKX2-1; HMGB1; EMX2; TBL1X; ZEB2; MYCBP; SOX11; TRIM16; PURA; ENO1; MED1; CDK7; TCERG1; ATF3; MYB; ZBTB20; CRK; ZNF91; EGR3; TCEA2; KAT6A; PCGF2
Down-regulation	97	TRIB3; TFAP2A; TEAD4; NRIP1; GMNN; RAD21; CDK9; WWC1; VAX2; THAP10; CDK2; NPAS2; USP22; NCOA3; ZNF580; WWP1; ZNF239; CREBL2; ERBB4; SIM2; MYBL1; PFDN5; PRDM2; ZHX2; HDAC9; TRPS1; SHOX2; E2F3; WT1; MED14; ZNF623; HOXD1; FOXF2; TAF10; EGR2; CUX2; CIZ1; TCEA1; TRIM29; HMGA1; CALCOCO1; ZNF331; MYRF; ETV4; ELF4; HOXD3; ZNF217; ZNF33B; SPI1; HIPK1; INSR; TTF2; PTTG1; HOXC6; IKBKAP; CCNH; HDAC1; SNAI2; MBD2; CBFA2T2; SSBP2; SMAD6; NR1H4; BHLHE41; TCF21; AHR; FOXC1; YAP1; ARID5B; SOX13; IL16; CBX4; CIITA; YBX1; EN1; ZBED2; INSM1; HIF1A; BCL11A; BNC2; GATA6; ZEB1; TDP2; KLF11; PBX3; TFAP2C; KAT2B; PEG3; SOX9; YBX3; ZNF589; MEIS1; NFATC3; ZFP36L2; TOX3; ZFPM2; HHEX