Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57034	Givinostat	GSE92742	NPC	Human	24h	10uM	EID0298

Response Information :

Types	Number	Response transcription factors
Up-regulation	89	STAT3; ERBB2; MED4; NR1D2; HMG20B; VPS72; SLC2A4RG; ALX1; CBX3; TOB1; RFX7; DEK; ZNF512B; RHOA; DNMT3B; THAP11; SMARCD1; CCNC; PMF1; IRF4; KAT7; DRAP1; MKL2; SOHLH2; MSC; BRD8; ZBTB38; RING1; CUX2; MAGED1; ZNF133; NR1I2; FLI1; DDX5; SIX1; NUP62; CREB5; SALL2; ZNF43; PRPF6; HLF; CTR9; EZH2; RXRA; ZBED4; RUVBL2; E2F3; HNRNPD; NAB1; MLLT10; ZNF292; CLOCK; TFCP2; BCL6; MAFF; CARHSP1; TOX; FOXD1; GTF2I; NEDD8; PRKDC; HDAC6; MYCN; CREBL2; ENO1; FOXJ3; ETV1; ZMYND8; SOX11; PHF20; VGLL4; PIR; HDAC9; SMAD1; ID4; ZBTB20; MNAT1; MEOX2; HMGB3; KDM5D; ZMIZ1; RBPMS; ZIC1; PLAGL1; HOXB2; TLE1; TCEA2; TWIST1; KAT6A
Down-regulation	89	ZHX2; CSDC2; TFDP1; FOXA1; TAF5L; HOXD10; IRF6; ZNF467; HDAC1; VGLL1; TBX21; NR2F1; BRD7; POU4F1; ELF1; EHF; TRIB3; CTCF; PFDN5; WNT4; CREB3L1; ETS1; MBD2; HOXB13; LYL1; RREB1; HIPK1; TAF9; SHOX2; MAF; CBFB; MYBL1; BBX; TFAP2C; CTNNB1; INSR; TBX3; SOX13; WWC1; ZNF165; TERF2; CEBPG; PAX5; FOXF2; HBP1; GFI1; AEBP1; TFAP2A; SPI1; INSM1; FOSB; DLX2; ZNF24; BAZ1A; FOXO1; CCNH; ZBED2; OSR2; LEF1; BRD4; ZNF232; MLXIP; BACH2; KLF11; SPEN; GATA6; BTG1; NR2F2; ATF3; MXI1; RFX5; IFI16; VDR; ZNF430; MYB; MAFB; HHEX; ID3; NFE2L2; CDK7; ZFPM2; PEG3; HIRA; ELF5; NFATC3; CRK; SPDEF; ID1; EGR1