Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57022	Alvocidib	GSE92742	NEU	Human	24h	10uM	EID0297

Response Information :

Types	Number	Response transcription factors
Up-regulation	101	MEF2C; SMARCD2; ZFHX3; PLAG1; POU2AF1; IKZF3; ZFY; UBTF; TBX2; SOX13; FOXN3; IRF6; KLF9; HOXA11; PGR; PBXIP1; TEAD4; SMARCB1; TCF20; KLF4; SOX17; ZNF764; PRDM10; ZBTB43; TLE2; FOXE1; MSX1; ATN1; SKI; SOX18; ZNF227; KDM5D; POU4F2; CAMTA1; ZBTB38; TCERG1; CALCOCO1; TCF4; SNAI2; ZNF141; ZNF10; HHEX; TCF3; INSR; MAFG; HOXC10; CARF; NFX1; FLI1; MAK; PLAGL2; ZNF652; ELF1; NKX2-1; MLXIP; PURA; HMGB3; NR4A1; SAP18; PRDM2; HSF1; FOSL2; HDAC1; FOXF2; NR3C2; IFI16; AES; PAX5; SHOX2; PPP1R13L; TAF1D; ZBTB20; CBFB; ZHX2; SALL1; DEAF1; ETS1; ZBTB16; LOXL2; PEG3; JUN; CSDE1; ZSCAN31; PTRF; EMX2; ZNF165; CALR; ZNF529; TXNIP; ZNF264; CDK7; DLX5; LEF1; BTF3; ZFP36L1; IKBKAP; MEIS1; CD3D; VDR; MNDA; TCEA2
Down-regulation	142	NRIP1; KDM5B; RBBP8; BRPF1; RHOA; BAZ1B; CDYL; MYCL; BASP1; OLIG2; REPIN1; ATF4; KAT2B; ZEB2; ZNF22; SIX2; WIZ; TRIP11; KLF13; ZKSCAN1; ZMIZ2; NLK; RLF; PSMC3IP; INSM1; WWTR1; CTBP2; ZNF302; ADNP2; FOXG1; SALL2; NFKB1; GLI3; PPARGC1A; CXXC1; CENPF; NUP62; NR2F1; SIRT2; SOX15; TRIM24; PHF20; ZNF24; RNF4; MDFI; ERBB4; MLXIPL; CRK; CNBP; SUPT5H; ZNF410; MXD4; TCEA1; CBX3; MLX; SMAD1; MYRF; PITX2; CTBP1; RBM39; CLOCK; SCAND1; SIRT7; PTTG1; SUB1; TCF12; ASCL1; ARL2BP; RBBP4; BRD8; PAX6; VPS72; CITED2; E2F5; WT1; HMGN3; DRAP1; ZNF217; CREB1; PHF1; ETV1; MBD2; MAGED1; PEX2; BMI1; CRYM; YBX1; RNF138; NPAS2; GATA6; SMAD4; ARID5B; SMARCD3; TAF10; TRIM16; SMAD6; DNMT3B; UBE2I; NAB1; DNAJC1; ZIC1; CRY1; ZNF146; FOXD1; ID2; TOX; MECOM; FOXA1; ATF5; SSX1; TRPS1; HMGA1; CEBPB; RBPMS; MYBL1; HBP1; MAFB; CEBPD; ISL1; SMAD7; NR1H3; RNF10; GTF3A; ABL1; ZFP36L2; NR2F2; BCL3; PBX1; ZBED2; ID4; TRIM29; TFEC; ZEB1; CCNE1; TOB1; FOXC1; CEBPZ; XBP1; HOXA5; DACH1; SOX9; HES1