Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57012	Givinostat	GSE92742	NEU	Human	24h	10uM	EID0297

Response Information :

Types	Number	Response transcription factors
Up-regulation	73	IKZF1; TCFL5; FOXO1; KLF13; KDM5C; IL16; LDB1; USP21; TBX21; VGLL1; GFI1; YAP1; HIC2; RUNX3; HDGF; BACH2; VPS72; ZNF711; ARNTL; PLAG1; SNAI1; ZNF117; RBM39; NHLH1; NLK; TCF3; CEBPB; ILF2; GATA1; TAL1; HOXB2; SNAI2; DDIT3; SREBF1; NEUROD1; MED15; HMGB3; SSX1; BACH1; TCF4; LEF1; STAT4; ECD; RORA; ELF1; ARL2BP; TRPS1; HIRA; KLF1; HOXB7; CARHSP1; DLX5; MXI1; HOXA1; RUNX1; TCF7; DNMT3B; BCL11B; ID2; MAF; CD3D; NR1H3; TGFB1; DLX2; ZNF512B; ID3; TFAP2C; TCF7L2; JUP; BTG1; ZBTB18; HOXA5; TRIB3
Down-regulation	112	PSIP1; ZMIZ1; KLF4; FOXO3; ZHX3; PCGF2; HIPK3; MAFF; SIM2; TLE2; HIVEP2; EGR1; EMX2; MITF; SETD3; SIX1; ZNF177; TOX; SMARCA2; ZFHX3; ING3; HOXB13; ETV5; NFIC; REPIN1; ZBTB38; SETD2; NANOG; IRX4; TAF11; PHF2; PIR; HMG20B; RBBP5; RBPJ; TFEB; WHSC1; CREB5; MEOX1; CUX2; AHR; NFIB; GTF2IRD1; NR1D2; NR3C2; ZNF432; TULP3; PSMC3IP; IRF5; ZNF350; NR2F2; PHIP; FHL2; KLF10; HNRNPD; MYCN; ZNF302; REST; BASP1; GMNN; MED1; ZNF426; ZNF32; MTDH; COPS5; NCOR2; ZNF606; ZKSCAN1; SFMBT1; ZNF468; CREBL2; OLIG2; EGR2; TEAD1; ZNF593; RNF138; RBBP8; DEK; YWHAB; WWC1; FOSL2; SALL1; ZSCAN31; TRIP6; ETS2; JUN; ARID1A; BATF3; ZNF3; ZNF136; ZNF268; ZSCAN18; EDF1; PCBD1; NR2F1; ZNF274; ISL1; JUND; NKX3-1; SATB1; TCF21; TAF10; ASCL1; NR4A2; ABL1; BCL3; SATB2; ZNF91; KDM5D; MAFB; EGR3; DACH1