Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID56994	Treprostinil	GSE92742	NEU	Human	24h	10uM	EID0296

Response Information :

Types	Number	Response transcription factors
Up-regulation	117	FOSL1; XBP1; EGR3; MEF2A; ELF5; STAT2; PRDM14; ELK3; THRAP3; SIX1; STAT3; MYBL2; HDAC7; VPS72; PRRX2; PLAGL2; BARX1; NFATC3; CCNC; MAFG; BTAF1; SERTAD2; NCOA2; KMT5A; TRIP11; TCF3; NR1H3; POU5F1B; TEAD3; TSHZ2; PDLIM1; RARG; PPRC1; ERG; CREB3L1; HMGA1; MDM2; HTATIP2; FOXF2; MEF2C; VDR; NELFB; ZBTB7A; RBBP5; MNAT1; ZNF117; ARID3B; LOXL2; NFATC4; HMGN3; COPS5; MECOM; HIF1A; KLF3; MYBL1; HOXB2; SP110; DLX5; FOSB; BCL11A; GTF3A; HIPK3; CRYM; DNMT3B; DAXX; PAX5; BRIP1; MYCL; SATB2; TFCP2L1; SPIB; HOXA11; NPAS2; ZNF281; NANOG; ATF5; EMX2; CNOT2; BCL10; STAT6; SOX13; SHOX2; TEAD4; BTG1; CUX1; SATB1; GATA2; KDM2A; ADRB2; AHR; HMGB3; ETS1; HOXD1; TBL1XR1; MNT; KDM5D; SIM2; ESR1; KLF4; CEBPB; TBL1X; DMTF1; TCF7L1; YWHAB; HOXB7; PHF20; SSBP2; SUZ12; DACH1; IFI16; HOXC10; ATF3; IRF6; CALR; JUP; ZFP36L1; ID4
Down-regulation	113	ZNF331; MNX1; APEX1; BTF3; PTTG1; PSMC3IP; DDX17; ZNF764; VEZF1; ZNF419; PBX1; FOXE1; PEG3; ZFP36L2; MLX; SMAD4; ZNF10; CITED1; GATA4; HOXD10; SAP18; HEY1; NRIP1; NEUROD1; ETV5; NR2F2; ZFPM2; MED1; BRD2; SUPT4H1; ZBTB18; PITX2; ZNF350; ZBTB38; BATF; HLF; ILF2; HHEX; ZNF692; ZNF248; CNBP; MXI1; HSF2; ZNF14; NFIC; BAZ1B; ZNF571; MITF; RERE; TWIST1; RXRA; ZSCAN31; FOXL2; ZNF177; ZNF274; ZFX; ZNF148; TXNIP; BRD8; LITAF; BNC2; ASCL1; NHLH2; CREM; ING3; ZNF493; HOXD11; ID3; ADNP; NR1D2; ZNF580; TAF9; SETD2; CBFB; WT1; NONO; HMGB1; BCL6; MEOX1; ZEB1; MEOX2; HIPK1; TFDP2; ELF1; TAL1; CERS6; MED24; AFF1; MYCN; MYT1; EZH2; CREBL2; NFIB; PURA; KAT7; MYB; HMGB2; CCNE1; NR2F1; BHLHE41; OLIG2; FLNA; ZNF302; BASP1; MAF; INSM1; SMARCA2; IRF4; GATA6; AEBP1; ZIC1; MAFB; ID1