Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID56989	Givinostat	GSE92742	NEU	Human	24h	10uM	EID0296

Response Information :

Types	Number	Response transcription factors
Up-regulation	157	FOSL1; ZNF586; RELB; EPAS1; IKZF1; HHEX; TAL1; PPARA; SOX9; KLF4; CDX1; NAB2; TBX1; TP73; KLF13; ASH1L; ARL2BP; VENTX; MAFF; FLI1; HIPK2; ZNF215; RORC; ARID5B; FOXC2; MNDA; ZBTB7B; PROP1; KLF3; BNC1; GFI1; FOXJ2; ING4; NKX2-5; IRX4; NFE2L2; NR4A3; NFKBIB; HIPK3; TFCP2L1; YAP1; CEBPE; EHF; HLX; RARG; CSDC2; PRDM1; IRF6; NFATC4; E2F4; BRD4; GON4L; ZNF331; GATA1; PRDM12; CEBPG; KLF7; ZBTB7A; NR0B2; ZNF654; HOXB1; THRB; NFE2L3; TAF1C; ZNF266; MED17; ARNTL2; LHX1; SIAH2; TBX21; RBL2; EGR3; ATOH1; TGFB1; MBD3; ZNF354A; CDK2; NFE2; TFCP2; MITF; LEF1; BCL6; SPI1; SKIL; EMX2; MECP2; PROX1; AR; TFEC; CD3D; ETV6; ZNF75D; FHL2; EGR2; ELK4; FOXI1; CCNH; ACTL6A; KLF9; GATA6; KAT2B; POU4F1; CITED2; MED21; MED25; HOXB5; TXNIP; VDR; CDX2; ELF5; FOXF2; FOXE1; WT1; ERF; HOXB2; MYBL1; DLX5; CREB3L2; HSF1; FOXA2; IFI16; CBX7; TFAP2C; ZNF544; KLF2; PPP1R13L; CREBL2; SOX18; FOXF1; CALR; GATA4; GATA2; HOXB13; MYCL; SOX17; ZNF573; VGLL1; TERF2; WNT4; MYC; LOXL2; ESR1; CNOT3; NR1H2; CBFB; ATF5; NR3C2; IRF9; ID4; ZFP36L1; BCL11A; CEBPB; SNAI2; CREB3L1; ETS1; TBX3; TRIM22
Down-regulation	260	CBX5; ZMYM2; NCOA2; PUF60; HIVEP1; PRDM4; USP22; SOX4; ZNF423; SMAD2; RNF111; BBX; HNRNPD; DPF2; CAMTA1; PSPC1; CREBZF; JARID2; SFPQ; UBE3A; BAZ2B; ADNP; TRIM28; RNF10; ING3; PIAS1; RBM14; TOX; TEAD1; APEX1; RBBP4; BRD8; MDFI; MAGED1; TAF4; SNW1; RNF4; CNOT2; CDYL; NCOA6; L3MBTL1; UBE2B; TRIM24; ZNF189; SMAD4; ING1; PRPF6; SIX1; BPTF; HSF2; SP3; MED4; CHD1; CDK8; NCOR2; BRF2; CTR9; TSC22D1; CBX3; PKNOX2; NEDD8; SOX11; MXD4; BMI1; NR2C1; TCERG1; ZBTB1; CCNA2; E2F3; PHOX2B; PCGF2; KAT6A; PBRM1; ISL1; ZNF532; PHF20; RNF138; E2F6; FOXD1; ZNF329; ZFP64; SOX15; MYCBP; MED13; TCF4; ETV5; REPIN1; SAFB2; SAP18; SOX12; MTF2; EBF2; TRIM33; GABPB1; BANP; KDM4A; NFE2L1; NUP62; MED1; PBX1; SETD3; C1D; SP140; ZNF536; SAFB; RSF1; SMARCE1; SALL2; BRD3; DRAP1; KAT7; CRK; RFC1; MEIS1; DNMT3B; ELK1; SMARCC1; MEN1; RREB1; ZNF146; BTF3; PATZ1; ZNF652; CRY1; HMGXB4; MEIS2; MYCN; TBL1XR1; CCNC; CREM; ZNF148; ABL1; HDAC6; NANOG; SUV39H1; NKX2-2; ZNF292; ZNF217; SMARCA5; MMS19; ZNF711; CARHSP1; HMG20A; ATF4; RAN; ASH2L; POU3F2; PBX3; ENO1; KAT6B; RBBP8; HLTF; TULP4; ZNF337; ARID4B; TSC22D2; ARID3B; TBP; POU5F1B; FOXO3; TRIP6; MTDH; VEZF1; RBBP5; PCGF3; SIX2; MED6; WHSC1; KDM5A; TRRAP; MSX1; AFF1; TAF1D; RCOR1; SOX2; ARID4A; BATF3; SREBF1; TDP2; TCF12; BAZ1A; ZMYND8; HMGN3; PEG3; PAXBP1; RBPMS; NFIL3; MED24; IRF7; ZFHX4; NR2F1; ZBTB11; DMTF1; SP110; MAK; PARP1; EDF1; RLF; MED23; TCF7; HMGB1; PIAS2; PIR; TERF1; ZNF84; SAP30; ZNF131; SND1; ZNF184; SMAD1; EP400; SMARCA4; TOB1; BASP1; YWHAB; KDM2A; KDM5D; FLNA; HMBOX1; TCEB2; ZNF512B; PCGF1; HOXA5; MYT1; LIN28A; ID2; CTNNB1; CHD7; BTAF1; SCAND1; RUNX3; PQBP1; PDLIM1; HTATIP2; ZNF160; TGIF1; DNAJC1; ASCL1; SUB1; ZNF24; SMAD3; RFX5; WWTR1; ERBB2; POU2AF1; STAT4; MKL2; HMGB3; KMT2A; IRF4; CREB1; TAF10; MNAT1; ZBTB38; ID3; EYA2; TCF7L1; HOXC6; HOXB7; TLE1