Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID56979	Varenicline	GSE92742	NEU	Human	24h	10uM	EID0295

Response Information :

Types	Number	Response transcription factors
Up-regulation	143	CEBPA; CEBPD; NFKBIB; FHL2; VPS72; CSDC2; ZNF32; MYBL1; DBP; RARG; CBX7; PCGF1; SP3; SIRT2; ERF; ARID5A; HOXA11; GATA6; ZNF124; ACTL6A; TCF7L2; VGLL1; TRIM29; ELF5; NFKB2; KLF13; MXI1; MBD2; TLE2; EZH1; LHX3; NR0B2; KDM5C; SPI1; CBL; BHLHE41; TAF5L; TAF9B; MYC; ZNF239; CBX6; MXD4; MYRF; ZNF232; NR0B1; PSMC3; IRF6; TGFB1; HDAC9; PTRF; ARNTL2; FOXL2; ST18; CEBPB; CREB3L2; MNDA; MED6; MED27; SSBP2; POLR3C; NFE2L2; NFE2L3; FOXC1; MYCL; HES1; BRIP1; SOX13; SP140L; HSF1; NR1H4; ZNF430; TFEB; EHF; FOXI1; NR1D2; TRIP6; NCOA3; TAL1; CD3D; ETS1; BCL11A; CEBPG; PAX6; ZBTB16; PIAS4; OSR2; ZNF573; TXNIP; CTBP2; CALR; SRCAP; LIMD1; HOXC10; ILF2; SAP30; ELF3; EPAS1; AGO2; SIRT7; TFAP2C; RXRA; EGR1; PHF1; ZNF264; GATA2; CNOT3; SMAD6; NFIC; RBBP8; SOHLH2; TCF21; CCNH; RUVBL2; KLF11; ID4; PIR; INSR; ZBED2; JAK2; MEF2A; RUVBL1; ZEB1; ATN1; JUP; WNT4; SOX9; ATF5; EN1; AES; ARID5B; IRF8; DLX2; TFDP2; IRF9; WT1; NFATC4; SSX1; ID1; POU2AF1; FLNA; GTF2A2; YBX3; CRK
Down-regulation	204	HIF1A; USP22; SREBF1; ZMYND8; RNF10; YWHAB; LZTS1; EP400; SOX2; PATZ1; ENY2; SMARCE1; SMARCA4; TWIST1; JARID2; NUP62; SPEN; SOX11; NFIL3; CBX5; TFDP1; BASP1; ZNF672; PPARGC1A; ZMIZ1; RAN; RNF4; MYCN; KDM5B; ZNF324; KLF2; CUX2; EBF2; ZNF84; MED4; BIRC2; ZNF423; SP110; KAT7; HIVEP2; ZNF629; TFAM; CHD3; TBP; SP140; CHD8; LOXL2; ZMYM2; ORC2; ZBTB40; LHX2; TGIF1; CCNC; STAT5A; UIMC1; ZNF783; ING1; RBPJ; RBBP4; MEN1; PRPF6; VGLL4; SMARCA5; CREBZF; NRBF2; MEOX1; TBPL1; POU3F2; ABL1; ZFHX4; NEDD8; MEOX2; DDX5; MAML1; PHF8; CAMTA1; NFKBIA; TP53; SAP18; DNMT3B; NRIP1; SOX12; SPDEF; MYCBP; CBX3; EYA1; NR2E1; KDM2A; MKL2; KAT6A; SMAD1; CNOT6; DEAF1; UBE2B; NCOR2; NPM1; TRAK1; HOXC4; GLI3; PREB; NFE2L1; MTDH; ASH2L; E2F5; TOX3; POU2F1; HLTF; CREB1; POU4F1; BRD2; HIVEP1; RBM14; EDF1; RERE; SNAI2; RORA; PCGF2; ZNF24; ZNF266; LPIN2; HSBP1; STAT4; LEF1; ZNF248; SND1; IRF7; PEG3; SMARCB1; ZBTB1; GTF2IRD1; STAT1; MSX1; NANOG; CHD7; TAF1D; TCF4; LHX6; NELFB; CTR9; MAX; FOXF1; PAX5; E2F3; KDM5D; HMBOX1; HIRA; TAF10; RLF; ZNF226; ARID1A; ZHX2; ID3; BRD3; TRRAP; NFKB1; HLF; PRRX1; ETV1; HEY1; KLF7; NCOA2; PLAGL2; FOXJ3; PDLIM1; HOXA5; ZNF512B; SIAH2; ZNF587; HOXC6; TSC22D1; CREM; HOXD1; CUX1; BACH2; KLF6; FOSL2; HIPK3; ZNF721; TLE4; BCL6; HOXB7; TCF7; BCL11B; TOX; HMGN3; BTG1; AEBP1; STAT5B; SIX1; TRPS1; TSC22D2; TRIM22; MAGED1; TCEA2; CREB3L1; ASCL1; FOXD1; ETS2; TBL1X; MTF2; MED1; EED; SMARCD2; EGR3