Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID56965	Givinostat	GSE92742	NEU	Human	24h	10uM	EID0295

Response Information :

Types	Number	Response transcription factors
Up-regulation	140	PPARD; PRDM4; TFAP2C; CEBPD; KLF15; ESRRG; HOXA11; NFKB2; NR1D2; NR0B1; ZNF215; TRIP6; TAF5L; TGFB1; MYBL2; TRPS1; FOXM1; DEK; TADA3; MDM2; MAF; HOXC11; MED27; ABT1; BAZ2A; RBBP7; ACTL6A; VDR; TRIM25; KDM5C; VPS72; PAX6; PSMC3; NFIB; FOXJ2; RBL2; TCF7L1; OSR2; GCFC2; CCNC; ZNF133; VGLL1; DLX5; SOHLH2; TFAP2A; GATA2; NR1H2; ZBTB16; KLF11; JUNB; FOXC1; ETS1; SFMBT1; HTATIP2; TCF21; PCGF1; ID2; HOXB13; GRHL2; NCOA1; ZXDC; SP140L; KLF13; ELF5; TP63; SSBP3; IKZF5; BRPF1; IRX4; THAP11; CEBPB; ZNF33B; NELFB; IRF6; PNRC1; BTG1; YEATS4; SMARCD2; ZBTB38; RING1; DNAJC1; KLF9; CIZ1; TWIST1; SLC2A4RG; ENY2; BMI1; WWTR1; OVOL2; ALX1; MAX; CEBPG; RUNX1; TFCP2L1; TCEA2; CTBP1; TBX3; MYBL1; AGO2; YBX3; PIR; SERTAD2; PLAGL2; MAZ; ZNF394; NFATC4; AES; NKX3-1; FOXO1; CNBP; HMGB2; INSR; CNOT3; EN1; RUVBL1; PBXIP1; HOXB7; CRYM; HDAC9; NR2F2; EHF; ATF5; MXI1; SAP30; FLNA; ZNF589; MAFB; TCF7L2; REL; NR2F6; RBBP8; BRD4; HOXB6; SPDEF; CRK; DMTF1; DLX2; LEF1; ESR1; PUF60
Down-regulation	147	LZTS1; ZNF131; SPEN; MED17; CAMTA1; HMGXB4; MYT1; ZEB1; PPARGC1A; SOX11; PATZ1; CUX2; PRDM10; NPAT; ZNF195; ZNF202; RERE; NANOG; ZBTB7A; PEG3; RSF1; MAFG; EP300; CREB5; BPTF; ZSCAN18; MYCN; NLK; ERG; CITED1; NCOA4; RNF111; ZMYND8; SOX2; PPRC1; NONO; BRD8; ZNF107; MZF1; TSG101; STAT5A; TRRAP; TSC22D2; ZNF544; MEOX1; NFKBIA; IRF2; SOX12; KMT2A; HLF; TCERG1; ARID4B; RCOR3; RBPMS; NPAS2; ZNF606; IRF7; NFX1; CARHSP1; APEX1; CREB1; INSM1; TCF25; ERBB2; SMARCA5; NR2E1; TP53; SIRT7; ZFPM2; CSDE1; BAZ1B; BCOR; KAT6B; ZKSCAN7; ZFHX4; TCEB2; MAGED1; ETS2; MED23; ZNF24; TCF4; BATF; MED13; REPIN1; SCAND1; PHF8; YAP1; BAZ2B; IRF4; NHLH2; PHF20; MYT1L; HMBOX1; BASP1; E2F5; FOXF1; TRIM16; EPAS1; PURA; PRRX1; TBL1XR1; ADNP; PITX2; FOXJ3; SMARCA1; SMAD1; RBFOX2; ZFHX3; TOX3; ATF4; YBX1; NR1I2; MED24; TAL1; PBX1; TLE4; SMAD4; PRKDC; RBBP5; AHR; DDIT3; CTR9; KLF4; CHD9; KDM2A; IRF1; IRF8; GTF2IRD1; BATF3; DDX17; CREB3L1; TOX; MEIS1; ETV1; ZBTB18; PITX1; CUX1; MEOX2; MKL2; ID1; CDK7; HEY2; STAT5B; ID3; PCGF2; EMX2; EGR1