Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID56909	Givinostat	GSE92742	HA1E	Human	6h	10uM	EID0293

Response Information :

Types	Number	Response transcription factors
Up-regulation	84	ADRB2; TBPL1; LMCD1; GLI2; NCOA3; MYCN; RUVBL2; HIVEP2; ENO1; CTR9; ZNF667; DNAJC1; PITX2; TEAD3; MYB; NFATC1; BCL11B; FOXO4; CBFA2T3; TBX1; E2F5; SPIB; SPEN; SETD3; RBBP5; CREG1; SOX4; POU4F1; MNAT1; NEDD8; ERG; BCL11A; GATA6; ZNF329; CDYL; TCF21; KLF6; STAT1; IRF7; PKNOX2; TSC22D4; CDK8; NR5A2; ZFHX3; NFE2L1; TOB1; ZNF281; CREB3L1; RYBP; YWHAB; CALR; RORA; NR3C2; URI1; SERTAD2; BIRC2; NPM1; PAWR; ZNF331; STAT3; ZSCAN18; CCNE1; MYCBP; IL16; MYRF; PPARD; MXI1; TOX3; RNF141; HTATIP2; CERS6; TCF4; IRF8; RBPMS; ASCL1; SIX1; FOXF1; ATF3; TOX; CREB1; AEBP1; NFIL3; CRK; CEBPA
Down-regulation	138	FOSL1; SUV39H1; PAX8; GABPB1; ERBB2; FHL2; NFKBIA; MYC; NUP62; MTA1; FOXM1; ATF1; ADNP; MAML1; ZHX2; TCERG1; NRIP1; ZNF532; NFE2L2; PRRX1; PMF1; PHF2; RREB1; PCGF3; CTCF; PRDM10; CTBP1; HSF1; PLAGL2; HOXB2; NCOA2; ZFP64; SMAD3; DEK; RBFOX2; MECOM; PRDM1; TBX21; EWSR1; GTF2I; HNRNPD; PCGF1; ZBTB14; PUF60; ELF1; CARHSP1; JAK2; RARB; TRIM29; NR2F1; YBX3; BHLHE40; SP140L; ELK3; NFKB1; IRF2; BCL6; NFE2L3; CHD3; FLNA; VEZF1; TP63; SP3; ZFP36L1; VPS72; TFAP2C; ZNF611; TGFB1I1; PBX3; HMGA2; MNT; PAX9; ZBTB38; HOXD11; USP22; ZNF226; ARL2BP; SMARCC1; BCL10; SREBF1; ZFP36L2; TTF2; KAT5; RFX5; HIRA; TRIP6; CSDE1; HOXD9; IFI16; CDK9; HIPK2; BRD3; ZNF410; ERBB4; SMARCA1; SPDEF; ELF5; ZNF91; MEIS2; MAFB; SMARCE1; SP2; HOXA10; FOXG1; FOXA1; POU2AF1; XBP1; SAFB2; ZNF652; RBL1; ETS1; ZNF721; BRD8; FOSL2; CHD8; NR1H2; NR0B1; EN1; HOXC4; ZNF232; UBE3A; ATF5; INSR; BRCA1; HIC2; IKZF1; ZMYND8; WWTR1; HOXA11; ESR1; ID4; TSC22D2; KAT6B; MEIS1; HOXA5; WT1; HOXC6; TBX2