Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID56901	Varenicline	GSE92742	HA1E	Human	6h	10uM	EID0292

Response Information :

Types	Number	Response transcription factors
Up-regulation	99	E2F2; CDK2; TBPL1; PSIP1; XBP1; MYCN; PMS1; BLZF1; PEG3; RB1; FUBP1; LYL1; PHIP; ZNF131; MAF; TAF9; EGR3; ADNP; SAP30; PRRX1; MED23; ZNF84; DDX17; ZMYND11; ZSCAN31; TFDP1; ZNF529; EHF; JAK2; AHR; ITGB3BP; RNF111; SPDEF; AFF1; ZNF146; TRIM22; ZEB2; ZBTB11; IFI16; GTF2A2; TRIB3; TAL1; BACH1; ZMYND8; TOX3; COPS2; RCOR1; HLTF; TULP4; ZNF248; SMARCA2; HSBP1; LIN28A; HMGB3; LEF1; CITED2; MNDA; MITF; BTAF1; CCNC; RFX5; ZNF573; ZBTB1; BAZ1A; HDAC4; HMGN3; HLF; KAT2B; NRIP1; MAFB; SUB1; HOXB2; ECD; SMARCA1; EGR2; ZNF302; CTBP2; TOX; BMI1; ERG; ZNF415; MEIS1; SNAI2; KLF10; HHEX; CEBPB; TBX3; ZNF83; ZBTB38; RUNX3; ESR1; ATF5; ZSCAN18; POU2AF1; TRPS1; WT1; ELK3; ZNF586; IKZF1
Down-regulation	102	PUF60; ABL1; ERBB2; CRK; SMARCD2; LOXL2; ZKSCAN1; FOXO3; SCAND1; NELFB; ZNF394; NFATC4; ZNF423; ELF3; HOXA5; SREBF1; MDM4; PRPF6; MEF2A; AIP; GTF2IRD1; LITAF; NFATC1; TRIM16; PKNOX2; HSF1; GATAD2A; CHD7; LHX3; MXD4; PMF1; TULP3; SIX2; ETS1; CDK9; STAT3; TCF7L1; RELB; CTBP1; FOXF2; NCOR2; YBX3; PBXIP1; NFE2L1; HOXA11; IRF9; LPIN2; TRRAP; MED27; KLF9; PTRF; TAF10; HEY1; PRRX2; PSMC3; PIR; TTF1; LMCD1; HMGB1; BCL3; EPAS1; TGFB1I1; IRF7; TP53; TEAD4; YWHAB; HOXC10; JUND; BRD4; ZHX2; PBX3; SALL2; SPEN; SLC2A4RG; NR4A1; NR2F1; CEBPA; ID1; RELA; ZNF652; TFDP2; ZFHX4; MAFF; PCGF2; NR1H2; ZIC1; SMAD7; AEBP1; DLX2; SOX4; HOXB7; XRCC6; ZNF91; TCF4; FOXC1; TRIP6; NFIB; ID4; TFAP2A; MXI1; ATF3; ZNF331