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Overview Perturbagen Expression Profiles Transcriptional Responses
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Overview Perturbagen Expression Profiles Transcriptional Responses
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Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID56885 Givinostat GSE92742 HA1E Human 6h 10uM EID0292
Types Number Response transcription factors
Up-regulation 109 TCFL5; CEBPD; KAT6B; STAT1; NCOA3; TRIB3; MAF; TBPL1; MNDA; HBP1; INSR; PBXIP1; NR5A2; HINFP; CREG1; SSBP2; NFIL3; ELF3; ZNF623; ADRB2; ZSCAN9; OSR2; TAF4B; VPS72; ZNF671; SIRT2; TRIM24; ZNF117; CRYM; ZNF124; NOC2L; TDP2; ZNF44; ZNF195; E2F5; MYCL; ZNF468; ZNF211; PPARD; ZNF611; HOXD1; ZNF107; CBFA2T3; CERS6; ZNF544; FOXA1; SUB1; ISL1; TCEA2; LDB1; ZNF551; PIAS1; RBPMS; SPDEF; TEAD3; IRF7; BCL11A; ZNF264; ZNF232; HDAC4; ZNF813; HMGB3; ACTL6A; ZNF350; LITAF; ZNF573; ZNF415; ZNF606; ZSCAN18; IRF3; TCF7L2; CITED2; SPIB; HLX; TOX3; ARNT2; ZNF329; IRF9; SOX11; IRF6; PEG3; NFE2; AR; ZNF331; ZNF432; JUNB; MNAT1; PAX5; PBX1; ST18; NKX2-1; NR4A2; ZNF587; NFIB; TCEB2; CEBPB; FOXC1; ZNF304; JUP; ID2; ZBED2; IRF8; TXNIP; TSC22D1; WT1; ESR1; NR2F2; ZNF586; INSM1
Down-regulation 172 MTA1; FOSL1; PAX8; FHL2; MYC; LOXL2; ERBB2; HOXA10; NFKBIA; SUV39H1; ATF1; HOXA5; SMAD3; NFKB1; GABPB1; CBFB; SIM2; HMGB2; HOXA7; USP22; IFNB1; PHIP; BRD3; ABL1; PHF2; STAT5A; HNRNPD; ADNP; NCOA6; HOXA11; ING2; BATF3; DEK; SIAH2; ZNF282; YAF2; HOXB7; NUP62; SMARCE1; RBM39; HIF1A; FOXD1; EGR3; HOXD10; EDF1; SMAD2; UBE3A; NCOR2; TRIP6; FOXM1; PUF60; TRIM29; PRPF6; NKX3-1; MED1; STAT6; PATZ1; RBM14; HOXC6; KLF9; FOXE1; KDM2A; NFATC1; HDAC6; JAK2; MTDH; RFX7; SALL1; ZBTB38; HMGA2; HOXC10; RNF111; PSMC3IP; BCOR; ZBTB1; WHSC1; GCFC2; MED15; ALX1; XBP1; BRPF1; BRD7; PMF1; SSX1; CIZ1; TGIF1; HDGF; ERF; SOX10; POLR2A; FOSL2; TCERG1; CCDC59; PIAS2; ITGB3BP; EED; LHX1; FUBP1; EGR2; REST; SETD2; BATF; RELA; ZFP64; UBE2I; TAF9; DDX17; ARNTL2; TGFB1I1; HOXD11; SAP30; TAF10; BAZ1A; PTTG1; NCOA2; USF2; ZEB2; HOXB6; PIR; ATN1; ZZZ3; DNAJC2; DAXX; MAFF; PRMT2; AATF; ZNF148; LIMD1; PRRX2; KLF3; SOX9; CCNA2; YEATS4; ZBTB20; MTF2; PURA; ZHX2; ZIC1; RREB1; NRIP1; VEZF1; BHLHE41; MBD2; BCLAF1; DMTF1; SERTAD2; SMARCC1; ING3; GATA4; NAB1; VGLL4; HMGN3; NFE2L1; PTRF; ATF5; ETS2; SFPQ; SMARCA1; KDM5D; KLF4; MAGED1; CRY1; HOXA1; ELK3; PBX3; KLF10; MECOM; BHLHE40; KLF6; IFI16; LEF1; IKZF1
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