Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID56868	Givinostat	GSE92742	ASC	Human	24h	10uM	EID0291

Response Information :

Types	Number	Response transcription factors
Up-regulation	77	JUN; TCF7L1; MYBL1; CALCOCO1; E2F3; MYBL2; SMARCB1; HOXC11; BARX1; CHAF1B; TWIST1; GRHL2; ARNTL2; APBB1; MED15; TRIB3; WHSC1; ZNF74; TTF2; PRDM14; DDIT3; RARG; OSR2; HOXB6; NCOA2; KDM5C; ZFP36L2; KLF5; SPDEF; RBPJ; ST18; DLX5; ATF3; HOXB5; TULP3; PA2G4; SUPT3H; ZNF117; TCEA1; VPS72; PRKDC; TP63; BNC2; SRCAP; RBBP7; NFATC4; NFE2L3; TGFB1; SMARCC2; DBP; TRIM33; TOB1; ELF3; CBX7; HIRA; SSX1; KLF11; WT1; SOHLH2; NKX2-1; TERF1; KLF13; CITED2; ARID5B; SOX9; MEIS2; DNMT1; TRPS1; ZNF589; BCL11A; ELF4; EN1; LEF1; TOX; KAT6A; FOXG1; NFATC3
Down-regulation	106	CRK; NR2F6; CEBPD; RBM14; XBP1; HLTF; MED6; NR2C1; ERBB2; COPS2; ORC2; IKZF5; ARID4A; ZNF302; ZBTB38; HTATIP2; ZBTB43; BATF3; MLX; ALX1; SFPQ; KAT7; SPEN; DPF2; CEBPA; RNF111; TBP; TEAD1; ZFP64; REPIN1; TBL1X; ZNF587; KLF9; STAT5A; SMAD4; RBBP5; NFKB1; CDK7; NPAS2; PCGF2; TRIP6; BAZ2B; NCOA4; ADNP; HLX; MXD1; UBP1; PPARGC1A; NAB1; NFKBIA; NR2F1; ZBTB11; CHD1; SKI; MED1; NKX3-1; WWTR1; TSC22D1; PTRF; C1D; TRRAP; HLF; CITED1; CRY1; CTNNB1; SP100; PIR; RB1; NR1H3; ING3; BMI1; SATB2; IRF8; RUVBL2; ZNF410; PIAS3; MYB; NFIB; ENO1; RARA; C1QBP; SUB1; CTR9; ZNF134; SSBP2; SMARCA4; ZMIZ1; TCF12; FOS; CBFB; CREG1; ZKSCAN1; ETV5; BAZ1A; KDM5D; ARID4B; HEY1; FOSL2; MEOX2; SIAH2; POU2AF1; ZEB2; NFIL3; EGR3; KDM5A; ZNF586