Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID56714	Exemestane	GSE92742	HA1E	Human	6h	10uM	EID0287

Response Information :

Types	Number	Response transcription factors
Up-regulation	329	RSF1; GATA3; PIR; STAT5A; TRPS1; MYB; MEF2C; MBD2; IRF4; USF2; PITX2; TWIST1; WHSC1L1; EED; MDM2; ZNF222; RFX7; ZNF329; RARA; URI1; FOXD1; BHLHE41; NCOA1; LZTS1; MED7; ELK1; NR1D2; YEATS4; ZBTB39; SKI; PPARD; HEY1; HMGB3; HLTF; IKZF2; ZIM2; CBFA2T3; CTR9; EGR3; SSX1; PPARG; NFATC1; NFAT5; MTF1; TFDP2; PLAGL1; SMARCA1; MAF; ADRB2; SIM1; KDM5D; IRF2; FOXO4; TXNIP; CD3D; THAP11; SMARCD2; XBP1; IRF5; ASCL1; SMARCA5; ZSCAN18; POLR2A; CXXC1; STAT2; NCOA3; RBL1; HTATIP2; NFE2L3; TTF2; ZKSCAN7; E2F8; ZNF586; ALX1; BNC2; PKNOX1; TBX2; ZNF764; KDM5A; EYA3; AFF4; ZFY; ING2; MXD1; HES1; IFNB1; ZBTB38; ZNF165; HMGA1; ZNF215; TSC22D3; ZNF33B; PNRC1; SUV39H1; HIF3A; ZNF302; CAMTA2; ZNF292; SSRP1; ZNF516; NCOA2; TRIM33; NFKBIB; HMG20A; FOXN2; EMX2; BCL10; TOPORS; NFYC; RELB; ZNF286A; NFIL3; HSF2; CBX6; SOX10; ELK4; TSC22D1; HCFC1; ZNF226; NR2F2; PARP1; E2F3; ATF6; HOXB3; ZMIZ2; KMT2A; ZFP64; GFI1; BACH2; SMARCA4; ZNF574; SMAD5; ELF3; TBPL1; FOXL2; BLZF1; ZKSCAN8; TAF1A; RUNX1; PBX2; NR1H3; RELA; KAT7; ZNF556; TFAP2A; TULP4; ZNF492; KLF6; MMS19; BRCA1; BTG1; RUVBL1; HOXA1; GLI2; CNOT6; EP400; ATF7; CCNE1; EBF2; ZNF184; HEY2; SMAD2; NPAT; IL16; KLF9; KLF2; MBD1; PEG3; PAX8; IRF6; MITF; NSD1; AGO2; ZNF443; SND1; KDM5B; ESR1; MEN1; GATA2; SP100; HMGA2; CUX1; RARG; ASH2L; RERE; NFKB1; CBX7; ZNF274; ZEB2; HIPK3; ZBTB24; ZNF721; L3MBTL1; LPIN2; PGR; NCOR2; LEF1; PHIP; PLAGL2; YBX2; TRIM22; NR3C1; TAF12; ZNF43; BAZ1A; EGR2; STAT3; HOXB2; MKL2; ZNF273; PRRX1; PCGF2; EZH2; FOXE1; PURA; ZIC1; MED1; PRPF6; SP140; ARID4A; STAT4; PKNOX2; ZHX3; SP1; CLOCK; HMG20B; PSMD9; BRD8; FOXC1; BCOR; WWP1; BRF2; ZNF217; MDM4; TMF1; SIX3; MYC; GABPB1; ADNP; SMAD4; RNF111; ZNF606; PRDM1; HLX; DNAJC1; NPAS2; CDC5L; ZNF528; POU2AF1; PLAG1; BAZ1B; SAP30; SAP130; TEAD1; MAGED1; FOXG1; FOXO1; ENO1; SPIB; RLF; SMARCA2; BRIP1; ZBTB44; SMARCD3; TCF4; HNRNPD; TFAP2C; ZNF14; IFI16; ZBTB1; NFATC3; HDAC6; IRF8; SMARCC2; IRF7; TFEC; AHR; RHOA; PPARGC1A; DNMT3B; CHD4; KLF3; ZMYND11; TCF7; HSBP1; ZBTB18; KLF4; RBM14; GATA4; EN1; HOXB7; CCNH; MYCBP; TSC22D2; DLX5; RBL2; ZBTB20; CREB3L2; MNT; RNF141; RUNX3; AFF1; BRD7; ID4; IRX5; TP53; SNAI2; CRYM; PITX1; ZNF160; TRIP6; ZNF415; ECD; AEBP1; MNDA; BATF3; ETS2; SOX17; HOXC10; ISL1; BMI1; ZFP36L2; SATB1; ZFPM2; KLF10; MAFB; HOXC6; MECOM; CRK
Down-regulation	307	PSIP1; NR2F6; IKBKAP; NRIP1; ABL1; APEX1; ERBB2; TCEA1; FOXO3; ENY2; SRCAP; ATF4; ZNF593; ZNF263; PCGF1; ING4; VPS72; IRF3; CHD8; RBM39; RFXANK; ZBTB17; MEIS1; ZNF787; HMGB1; CENPF; JUND; NEDD8; ZNF446; PMS1; ZNF500; TOX; NPAS1; CBX3; MED27; DDIT3; ZNF202; REL; MED21; HOXD13; GATA6; RNF4; SIRT7; CERS4; ETV4; ZNF576; PRRX2; TOX4; NFIB; ZNF219; DLX2; KDM4C; PCGF3; ATF1; ATF5; CREB5; HSF4; CBX4; ZSCAN5A; SMAD3; CCNC; CAMTA1; ZNF473; TCF15; CALR; SIN3B; HMGB2; CAPN15; SUPT7L; PHF20; RNF138; ZNF177; SUMO1; CNOT3; TONSL; SOX15; REXO4; ITGB3BP; AES; TADA3; HOXB13; TBX10; E2F4; XRCC6; SOX9; IRX4; SCAND1; HOXD9; FUBP1; ERBB4; ZNF337; TLX2; RUVBL2; HOXA7; HOXD11; NELFB; SMARCD1; AIP; PSMC3; NKX2-2; NKX3-2; TCF3; TAF6; CITED2; RBFOX2; MED16; AR; PHF2; TRIB3; ZNF350; ZNF668; HOXA6; ZNF133; NR1H2; SNAPC4; PAX6; NR5A1; GTF3A; USP21; E4F1; MED25; TBP; ARNTL2; NR4A2; ZMYND8; ZNF654; ZNF276; CHD1; TULP3; FOXF2; PA2G4; PRDM4; CENPB; LOXL2; SUPT3H; ZNF692; ARHGAP35; POU4F3; CREB3; APBB1; FOXM1; RXRA; ZFHX3; LHX1; ERF; MEOX1; WWTR1; TCEB2; JUP; MZF1; ZNF444; KLF1; RAD21; ZNF268; ZNF335; SAFB2; OVOL2; PAXBP1; ZNF34; EGR1; COPS5; CCNT1; MEF2A; DEAF1; ARL2BP; DEK; EDF1; ZNF384; TGIF1; PIAS1; ZSCAN32; UBTF; TEAD4; SAP18; BIRC2; CNBP; LYL1; HOXD10; SMAD7; C1D; ZNF281; RYBP; NR0B1; LITAF; PAWR; ZMIZ1; CEBPD; PQBP1; RREB1; TCF7L2; EP300; NFRKB; DACH1; DAXX; RCOR1; PRDM14; HDGF; FOXF1; MAFG; PSPC1; ZNF562; HOXA4; CCDC59; MNAT1; MXD4; MTF2; CRY1; ZNF410; CHD7; RING1; CIZ1; ZNF140; GFI1B; JARID2; SOX11; NR2C1; ZNF430; SOX4; ZNF432; IKZF5; ZNF580; HDAC7; HOXD1; HOXD3; RNF6; ZNF83; KLF7; PBXIP1; BHLHE40; SFPQ; WWC1; PMF1; PEX2; KLF5; CBFB; SP140L; TOB1; NR4A1; ERG; PFDN5; SUB1; RBBP7; ZNF589; PTRF; CARHSP1; PTTG1; HIRA; MAZ; WT1; MEOX2; RFX5; NKX3-1; YAP1; CEBPB; ORC2; ZNF146; UBE3A; SATB2; ZBED1; VGLL1; TLE2; FOXK2; CDYL; ZNF394; BRD3; TRIM16; MEIS2; BCL6; TAF9B; PBX1; ZNF91; SMAD6; SPEN; RORA; ZNF131; SRF; SIX1; TDP2; FOXN3; CEBPZ; VGLL4; CITED1; TBL1XR1; NAB1; CREB1; ATF3; TOX3; ZMYM2; SALL2; CUX2; DMTF1; HOXA5; SMAD1; ZBED2; INSM1; ELK3; FOS; ZHX2; ID2; SALL1; STAT1; PBX3; ID3; CTBP2; PDLIM1; ARID5B; MXI1